IntraVoxel Incoherent Motion (IVIM) MRI of fetal lung and kidney: Can the perfusion fraction be a marker of normal pulmonary and renal maturation?
Diffusion
Fetal kidney
Fetal lung
IntraVoxel Incoherent Motion (IVIM)
Magnetic Resonance Imaging (MRI)
Organ development
Perfusion
Journal
European journal of radiology
ISSN: 1872-7727
Titre abrégé: Eur J Radiol
Pays: Ireland
ID NLM: 8106411
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
16
06
2020
revised:
30
03
2021
accepted:
14
04
2021
pubmed:
26
4
2021
medline:
19
5
2021
entrez:
25
4
2021
Statut:
ppublish
Résumé
To investigate the use of IntraVoxel Incoherent Motion (IVIM) MRI in the study of microstructural tissue changes occurring in fetal lung and kidney during gestation. 34 normal pregnancies were enrolled. Patients were divided into two groups based on gestational age (GA): group A (21-29 weeks) and group B (30-39 weeks). MR examinations were performed at 1.5T, with a standard fetal MR protocol including a Diffusion-Weighted Echo-Planar Imaging sequence with 10 different b-values (0, 10, 30, 50, 75, 100, 200, 400, 700, 1000s/mm In renal ROIs a positive correlation between f The IVIM perfusion fraction f may be considered as a potential marker of pulmonary and renal maturation in relation to hemodynamic changes described in intrauterine life. Our results highlight that IVIM model is useful as an additional prenatal diagnostic tool to study lung and renal development.
Identifiants
pubmed: 33895624
pii: S0720-048X(21)00206-0
doi: 10.1016/j.ejrad.2021.109726
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
109726Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.