Deuterium metabolic imaging - Back to the future.


Journal

Journal of magnetic resonance (San Diego, Calif. : 1997)
ISSN: 1096-0856
Titre abrégé: J Magn Reson
Pays: United States
ID NLM: 9707935

Informations de publication

Date de publication:
05 2021
Historique:
received: 22 12 2020
revised: 29 01 2021
accepted: 02 02 2021
entrez: 27 4 2021
pubmed: 28 4 2021
medline: 24 12 2021
Statut: ppublish

Résumé

Deuterium metabolic spectroscopy (DMS) and imaging (DMI) have recently been described as simple and robust MR-based methods to map metabolism with high temporal and/or spatial resolution. The metabolic fate of a wide range of suitable deuterated substrates, including glucose and acetate, can be monitored with deuterium MR methods in which the favorable MR characteristics of deuterium prevent many of the complications that hamper other techniques. The short T

Identifiants

pubmed: 33902815
pii: S1090-7807(21)00021-5
doi: 10.1016/j.jmr.2021.106932
pmc: PMC8083995
mid: NIHMS1679645
pii:
doi:

Substances chimiques

Acetates 0
Water 059QF0KO0R
Deuterium AR09D82C7G
Glucose IY9XDZ35W2

Types de publication

Journal Article Research Support, N.I.H., Extramural Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

106932

Subventions

Organisme : NIBIB NIH HHS
ID : R01 EB025840
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Henk M De Feyter (HM)

Departments of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, CT, USA. Electronic address: henk.defeyter@yale.edu.

Robin A de Graaf (RA)

Departments of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, CT, USA. Electronic address: robin.degraaf@yale.edu.

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Classifications MeSH