Presumptive neural microsporidiosis in a young adult German Shepherd dog from rural Australia.
dog
meningoencephalitis
microsporidia
Journal
Australian veterinary journal
ISSN: 1751-0813
Titre abrégé: Aust Vet J
Pays: England
ID NLM: 0370616
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
revised:
21
02
2021
received:
06
12
2020
accepted:
27
03
2021
pubmed:
28
4
2021
medline:
7
8
2021
entrez:
27
4
2021
Statut:
ppublish
Résumé
A 1-year-old, neutered male German Shepherd was presented with a 5-month history of episodic lethargy, intermittent fever, weight loss and a hunched posture. The dog was diagnosed with presumptive microsporidian meningoencephalitis based on cytological findings on cerebrospinal fluid analysis and a positive PCR test. The dog initially responded favourably to a 4-week course of trimethoprim-sulfadiazine, pyrimethamine and fenbendazole, and remained well for 12 weeks following cessation of treatment. Disease then recurred, and despite an initial positive response to treatment, he deteriorated and was euthanased 11 weeks later, 7.5 months after definitive diagnosis and 13 months after clinical signs were first reported. To the authors knowledge, this is the first case of canine microsporidiosis in Australia.
Substances chimiques
Trimethoprim
AN164J8Y0X
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
351-355Informations de copyright
© 2021 Australian Veterinary Association.
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