Massive intraperitoneal hemorrhage in patients with COVID-19: a case series.
COVID-19
Coagulopathy
Disseminated intravascular coagulation
Thrombotic microangiopathy
Journal
Journal of thrombosis and thrombolysis
ISSN: 1573-742X
Titre abrégé: J Thromb Thrombolysis
Pays: Netherlands
ID NLM: 9502018
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
accepted:
13
04
2021
pubmed:
29
4
2021
medline:
22
7
2021
entrez:
28
4
2021
Statut:
ppublish
Résumé
Coronavirus disease (COVID-19) initiates several life-threatening complications including coagulopathies with a unique characteristic that made this problem challenging. Here we presented 4 cases of RT-PCR positive patients that have experienced deadly intraperitoneal hemorrhage with fourth WHO Bleeding Grade after overcoming their respiratory phase. COVID-19 could induce several coagulopathies with different features that besides iatrogenic interventions increases its mortality and morbidity due to lack of clinical evidence based on well-designed randomized clinical trials on anticoagulation therapies (AT) and administration of varieties of newly approved and non-approved medicines. This report showed the urgent need for investigation on the pathophysiology of COVID-19-associated coagulopathy esp. in hemorrhagic events which are needed to make the best therapeutic decision.
Identifiants
pubmed: 33909261
doi: 10.1007/s11239-021-02447-x
pii: 10.1007/s11239-021-02447-x
pmc: PMC8079832
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
338-344Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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