Physiology and Pathology of Contractility of the Myometrium.
Myometrium
contractility
gestation
postpartum hemorrhage
review
uterine atony
Journal
In vivo (Athens, Greece)
ISSN: 1791-7549
Titre abrégé: In Vivo
Pays: Greece
ID NLM: 8806809
Informations de publication
Date de publication:
Historique:
received:
02
01
2021
revised:
16
02
2021
accepted:
19
02
2021
entrez:
29
4
2021
pubmed:
30
4
2021
medline:
22
6
2021
Statut:
ppublish
Résumé
Uterine atony is a serious obstetrical complication since it is the leading cause of postpartum hemorrhage. Postpartum hemorrhage (PPH) is one of the 5 major causes of postpartum mortality; therefore, it requires immediate medical intervention, independent of whether delivery occurs normally or with a cesarean section. While in the past years most cases of postpartum hemorrhage were caused due to uterine atony following vaginal delivery, in recent years most PPH cases indicate a significant association with cesarean delivery. There are several methods used in order to avoid such a life-threatening complication, ranging from risk assessment to prevention, and finally medical intervention and management, if such an event occurs. In this scientific paper emphasis is given on the so-called "uterotonic" agents that are currently used, including oxytocin among others. It is, therefore, important to be familiar with these agents as well as understand the physiological mechanism by which they work, since they are used in everyday practice, not only for managing but also for preventing PPH. There are several potential questions that arise from the use of such "uterotonic" agents, and most specifically of oxytocin. Maybe one of the most important issues is the determination of optimal dosing of oxytocin in order to avoid PPH after a cesarean section.
Identifiants
pubmed: 33910817
pii: 35/3/1401
doi: 10.21873/invivo.12392
pmc: PMC8193291
doi:
Substances chimiques
Oxytocics
0
Oxytocin
50-56-6
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1401-1408Informations de copyright
Copyright© 2021, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
Références
Cochrane Database Syst Rev. 2018 Jun 07;6:CD005456
pubmed: 29879293
Purinergic Signal. 2014 Mar;10(1):157-87
pubmed: 24271059
J Adv Pharm Technol Res. 2018 Jul-Sep;9(3):102-106
pubmed: 30338236
Am J Obstet Gynecol. 2015 Jul;213(1):76.e1-76.e10
pubmed: 25731692
Int J Dev Biol. 2014;58(2-4):95-106
pubmed: 25023675
Semin Cell Dev Biol. 2007 Jun;18(3):321-31
pubmed: 17613262
Cold Spring Harb Perspect Biol. 2011 Sep 01;3(9):a004549
pubmed: 21709182
Semin Perinatol. 2019 Feb;43(1):27-34
pubmed: 30578144
Prog Biophys Mol Biol. 2011 Oct;107(1):183-92
pubmed: 21777604
J Pak Med Assoc. 2006 Dec;56(12):572-5
pubmed: 17312645
J Soc Gynecol Investig. 2002 Sep-Oct;9(5):265-75
pubmed: 12383910
Am J Obstet Gynecol. 1981 Jun 1;140(3):254-60
pubmed: 7246625
Am J Obstet Gynecol. 2018 Jan;218(1):122.e1-122.e8
pubmed: 29138035
J Matern Fetal Neonatal Med. 2005 Sep;18(3):149-54
pubmed: 16272036
J Pregnancy. 2013;2013:525914
pubmed: 24363935
Anat Rec A Discov Mol Cell Evol Biol. 2006 Jan;288(1):84-90
pubmed: 16345078
BMJ. 2011 Aug 01;343:d4661
pubmed: 21807773
Trials. 2019 Jan 3;20(1):4
pubmed: 30606246
Int J Womens Health. 2016 Nov 02;8:647-650
pubmed: 27843354
Acta Obstet Gynecol Scand. 2005 Mar;84(3):266-9
pubmed: 15715535
J Cell Mol Med. 2009 Oct;13(10):4268-82
pubmed: 19732238
Sci Rep. 2020 Oct 1;10(1):16221
pubmed: 33004882
Physiol Rev. 2001 Apr;81(2):629-83
pubmed: 11274341
Obstet Gynecol. 2019 Dec;134(6):1308-1316
pubmed: 31764744
Obstet Gynecol. 2011 Jan;117(1):21-31
pubmed: 21173641
Am J Obstet Gynecol. 2002 Mar;186(3):496-8
pubmed: 11904613
Ann N Y Acad Sci. 2007 Apr;1101:72-84
pubmed: 17442780
Best Pract Res Clin Obstet Gynaecol. 2019 Nov;61:3-14
pubmed: 31326333
Curr Biol. 2000 May 4;10(9):491-500
pubmed: 10801437
J Clin Hypertens (Greenwich). 2011 Sep;13(9):687-9
pubmed: 21896151
Int J Pharm Compd. 2006 Mar-Apr;10(2):156-8
pubmed: 23974190
Exp Physiol. 2001 Mar;86(2):239-46
pubmed: 11429640
Biol Cybern. 2006 Jan;94(1):2-8
pubmed: 16341542
Transl Oncol. 2018 Apr;11(2):259-267
pubmed: 29413758
Semin Reprod Med. 2009 Jul;27(4):330-7
pubmed: 19530067
Psychophysiology. 2017 Feb;54(2):279-288
pubmed: 28118687
Semin Cell Dev Biol. 2007 Jun;18(3):289-95
pubmed: 17659954
Curr Opin Anaesthesiol. 2019 Jun;32(3):278-284
pubmed: 31045634
Obstet Gynecol. 2006 Oct;108(4):1039-47
pubmed: 17012482
PLoS One. 2018 Sep 25;13(9):e0203810
pubmed: 30252860
Cochrane Database Syst Rev. 2014 Oct 09;(10):CD009701
pubmed: 25300173
Cochrane Database Syst Rev. 2007 Jul 18;(3):CD005457
pubmed: 17636798
Cell. 2014 Nov 6;159(4):738-49
pubmed: 25417152
J Matern Fetal Neonatal Med. 2020 Nov;33(22):3740-3745
pubmed: 30836810
Am J Physiol. 1978 Nov;235(5):C168-79
pubmed: 727239
Adv Biosci. 1973;9:751-60
pubmed: 4805887
Cochrane Database Syst Rev. 2019 Apr 29;4:CD001808
pubmed: 31032882
Am J Obstet Gynecol. 2013 Jul;209(1):51.e1-6
pubmed: 23507549
Best Pract Res Clin Obstet Gynaecol. 2018 Oct;52:68-87
pubmed: 29866432
Syst Rev. 2018 Oct 11;7(1):156
pubmed: 30305154
Comput Biol Med. 2016 Oct 1;77:182-94
pubmed: 27567400
Reprod Biol Endocrinol. 2016 Jun 14;14(1):33
pubmed: 27301276
Hum Reprod Update. 2005 May-Jun;11(3):293-307
pubmed: 15790602
Reprod Health. 2016 Apr 14;13:38
pubmed: 27080710
Am Anthropol. 2011;113(3):417-30
pubmed: 21909154
Am J Obstet Gynecol. 1979 Feb 1;133(3):308-15
pubmed: 433992