Dyshidrosiform Bullous Pemphigoid.

blister bullous corticosteroid dyshidrosiform dyshidrosis dyshidrotic elderly pemphigoid pompholyx vesicle

Journal

Medicina (Kaunas, Lithuania)
ISSN: 1648-9144
Titre abrégé: Medicina (Kaunas)
Pays: Switzerland
ID NLM: 9425208

Informations de publication

Date de publication:
20 Apr 2021
Historique:
received: 26 03 2021
revised: 13 04 2021
accepted: 19 04 2021
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 15 5 2021
Statut: epublish

Résumé

Dyshidrosiform bullous pemphigoid is a variant of bullous pemphigoid. At least 84 patients with dyshidrosiform bullous pemphigoid have been described. Dyshidrosiform bullous pemphigoid usually presents with pruritic blisters in elderly individuals; the hemorrhagic or purpuric lesions on the palms and soles can be the only manifestation of the disease. However, bullae may concurrently or subsequently appear on other areas of the patient's body. Patients typically improve after the diagnosis is established and treatment is initiated. The mainstay of therapy is systemic corticosteroids, with or without topical corticosteroids, and systemic dapsone or immunosuppressants. Drug-related or nickel-induced dyshidrosiform bullous pemphigoid improves after stopping the associated agent; however, systemic therapy has also been required to achieve resolution of the blisters. Similar to classic bullous pemphigoid, neurologic conditions and psychiatric disorders have been observed in dyshidrosiform bullous pemphigoid patients. The new onset of recurrent or persistent blisters on the palms, soles, or both of an elderly individual should prompt the clinician to consider the diagnosis of dyshidrosiform bullous pemphigoid.

Identifiants

pubmed: 33924249
pii: medicina57040398
doi: 10.3390/medicina57040398
pmc: PMC8074754
pii:
doi:

Substances chimiques

Immunosuppressive Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Philip R Cohen (PR)

San Diego Family Dermatology, National City, CA 91950, USA.
College of Osteopathic Medicine, Touro University California, Vallejo, CA 94589, USA.
Scripps Family Medicine Residency, Scripps Mercy Hospital Chula Vista, Chula Vista, CA 91910, USA.
Family Medicine Residency, Family Health Centers of San Diego, San Diego, CA 92122, USA.
Davis Medical Center, Department of Dermatology, University of California Davis, Sacramento, CA 95814, USA.

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Classifications MeSH