Overexpression of
Animals
Auditory Perception
/ genetics
Auditory Threshold
/ physiology
Brain
/ physiology
Evoked Potentials, Auditory, Brain Stem
/ physiology
Female
Gene Expression
/ genetics
Hearing
Humans
Inferior Colliculi
/ metabolism
LIM-Homeodomain Proteins
/ genetics
Male
Mice
Mice, Transgenic
Neurons
/ physiology
PAX2 Transcription Factor
/ genetics
Promoter Regions, Genetic
/ genetics
Transcription Factors
/ genetics
auditory system
inferior colliculus
inhibition
sound processing
transcription factor ISL1
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
26 Apr 2021
26 Apr 2021
Historique:
received:
17
03
2021
revised:
19
04
2021
accepted:
20
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
4
6
2021
Statut:
epublish
Résumé
The LIM homeodomain transcription factor ISL1 is essential for the different aspects of neuronal development and maintenance. In order to study the role of ISL1 in the auditory system, we generated a transgenic mouse (
Identifiants
pubmed: 33925933
pii: ijms22094507
doi: 10.3390/ijms22094507
pmc: PMC8123449
pii:
doi:
Substances chimiques
LIM-Homeodomain Proteins
0
PAX2 Transcription Factor
0
PAX2 protein, human
0
Pax2 protein, mouse
0
Transcription Factors
0
insulin gene enhancer binding protein Isl-1
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Grantová Agentura České Republiky
ID : 20-06927S
Organisme : Akademie Věd České Republiky
ID : 86652036
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