Patents and technology transfer in CRISPR technology.

Animals CRISPR-Cas Systems / genetics Genetic Techniques Licensure Patents as Topic SARS-CoV-2 / isolation & purification Technology Transfer
CRISPR Cpf1 Mammoth biosciences Non-mammalian system SHERLOCK

Journal

Progress in molecular biology and translational science
ISSN: 1878-0814
Titre abrégé: Prog Mol Biol Transl Sci
Pays: Netherlands
ID NLM: 101498165

Informations de publication

Date de publication:
2021
Historique:
entrez: 3 5 2021
pubmed: 4 5 2021
medline: 12 5 2021
Statut: ppublish

Résumé

CRISPR technology has revolutionized biological research in the last decade and many academic institutions and companies have patented CRISPR systems and applications. Several patents have been filed for various applications of CRISPR in different industries such as agriculture, synthetic biology, bio-nanotechnology and precision medicine. Despite tremendous pressure on the technology transfer teams, several startups and spin-out companies are already using CRISPR technologies for commercial applications. In this chapter, we discuss the different CRISPR nucleases and their applications. Secondly, we detail our current opinion and perspective on the CRISPR patent and technology landscape for non-mammalian systems. We present two case-studies on CRISPR diagnostics companies, SHERLOCK and Mammoth Biosciences, who are currently at the forefront of establishing diagnostics platforms for coronavirus (SARS-CoV-2) detection. Finally, our chapter identifies future advancements and possible challenges that CRISPR technology might face in non-mammalian systems.

Identifiants

DOI: 10.1016/bs.pmbts.2021.01.009 PMID: 33934836
pubmed: 33934836
pii: S1877-1173(21)00020-X
doi: 10.1016/bs.pmbts.2021.01.009
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

153-182

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Lichelle Grobler (L)

Synthetic Nanobiotechnology and Biomachines Group, ERA Synthetic Biology, Centre for Synthetic Biology and Precision Medicine, CSIR, Pretoria, South Africa.

Essa Suleman (E)

Veterinary Molecular Diagnostics and Vaccines, Medical Devices and Diagnostics Impact Area, CSIR, Pretoria, South Africa.

Deepak B Thimiri Govinda Raj (DB)

Synthetic Nanobiotechnology and Biomachines Group, ERA Synthetic Biology, Centre for Synthetic Biology and Precision Medicine, CSIR, Pretoria, South Africa. Electronic address: dgovindaraj@csir.co.za.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Patents and technology transfer in CRISPR technology.
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › Systèmes CRISPR-Cas › Patents and technology transfer in CRISPR technology.
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Patents and technology transfer in CRISPR technology.
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Assurance de la qualité des soins de santé › Délivrance de titres et certificats › Autorisation d'exercer › Patents and technology transfer in CRISPR technology.
questionsmedicales.fr › Organisations et économie des soins de santé › Contrôle social formel › Jurisprudence › Propriété intellectuelle › Brevets comme sujet › Patents and technology transfer in CRISPR technology.
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Nidovirales › Coronaviridae › Coronavirus › Betacoronavirus › Virus du SRAS › SARS-CoV-2 › Patents and technology transfer in CRISPR technology.
questionsmedicales.fr › Sciences de l'information › Communication › Diffusion des innovations › Tranfert de technologie › Patents and technology transfer in CRISPR technology.