Immune Profile in Patients With COVID-19: Lymphocytes Exhaustion Markers in Relationship to Clinical Outcome.
COVID-19
SARS-CoV-2
clinical outcome
immune cells exhaustion
immunologic predictors
Journal
Frontiers in cellular and infection microbiology
ISSN: 2235-2988
Titre abrégé: Front Cell Infect Microbiol
Pays: Switzerland
ID NLM: 101585359
Informations de publication
Date de publication:
2021
2021
Historique:
received:
27
12
2020
accepted:
24
03
2021
entrez:
3
5
2021
pubmed:
4
5
2021
medline:
22
6
2021
Statut:
epublish
Résumé
The velocity of the COVID-19 pandemic spread and the variable severity of the disease course has forced scientists to search for potential predictors of the disease outcome. We examined various immune parameters including the markers of immune cells exhaustion and activation in 21 patients with COVID-19 disease hospitalised in our hospital during the first wave of the COVID-19 pandemic in Slovakia. The results showed significant progressive lymphopenia and depletion of lymphocyte subsets (CD3
Identifiants
pubmed: 33937096
doi: 10.3389/fcimb.2021.646688
pmc: PMC8082075
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
646688Informations de copyright
Copyright © 2021 Bobcakova, Petriskova, Vysehradsky, Kocan, Kapustova, Barnova, Diamant and Jesenak.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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