The Influence of Perceived Dapivirine Vaginal Ring Effectiveness on Social Disclosure and Ring Adherence.
Adherence
Dapivirine vaginal ring
HIV prevention
Social support
Journal
AIDS and behavior
ISSN: 1573-3254
Titre abrégé: AIDS Behav
Pays: United States
ID NLM: 9712133
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
accepted:
23
04
2021
pubmed:
4
5
2021
medline:
23
11
2021
entrez:
3
5
2021
Statut:
ppublish
Résumé
We analyzed data from 1428 users of the dapivirine vaginal ring, who participated in the MTN-020/ASPIRE phase III trial and subsequent open-label extension MTN-025/HOPE trial, to examine relationships between perceived ring protection, social disclosures, and self-reported ring adherence. In HOPE, 77% perceived the ring to be highly effective, and this view was associated with speaking: (a) to a greater number of people about the study, (b) with other participants, (c) to more people who were in favor of the ring, and (d) to more people whose opinions were valued. Reported adherence was not directly associated with perceived protection but was associated with disclosing to someone who was in favor of the ring. These findings suggest the importance of women's internalized ideas about the protective benefits of the DVR in sharing information about the ring and the importance of social support on adherence.
Identifiants
pubmed: 33939034
doi: 10.1007/s10461-021-03286-w
pii: 10.1007/s10461-021-03286-w
pmc: PMC8563504
mid: NIHMS1740628
doi:
Substances chimiques
Anti-HIV Agents
0
Pyrimidines
0
Dapivirine
TCN4MG2VXS
Types de publication
Clinical Trial, Phase III
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4169-4179Subventions
Organisme : NIAID NIH HHS
ID : UM1 AI069423
Pays : United States
Organisme : NIH HHS
ID : UM1AI106707
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI068633
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI068615
Pays : United States
Organisme : NIH HHS
ID : UM1AI068633
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI106707
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI069518
Pays : United States
Organisme : NIH HHS
ID : UM1AI068615
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI069436
Pays : United States
Organisme : NIAID NIH HHS
ID : U01 AI069436
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI069469
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI069530
Pays : United States
Investigateurs
Jared Baeten
(J)
Thesla Palanee-Phillips
(T)
Nyaradzo Mgodi
(N)
Elizabeth Brown
(E)
Lydia Soto-Torres
(L)
Katie Schwartz
(K)
Ashley Mayo
(A)
Bonus Makanani
(B)
Francis Martinson
(F)
Lameck Chinula
(L)
Linda-Gail Bekker
(LG)
Gonasagrie Nair
(G)
Vaneshree Govender
(V)
Samantha Siva
(S)
Zakir Gaffoor
(Z)
Logashvari Naidoo
(L)
Arendevi Pather
(A)
Nitesha Jeenarain
(N)
Gita Ramjee
(G)
Dishiki Kalonji
(D)
Nishanta Singh
(N)
Leila Mansoor
(L)
Flavia Matovu
(F)
Brenda Gati
(B)
Portia Hunidzarira
(P)
Felix Mhlanga
(F)
Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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