Failure of anterior skull base reconstruction for sinonasal carcinoma: consequence on the postoperative follow up. A multicentre evaluation of management.


Journal

Acta oto-laryngologica
ISSN: 1651-2251
Titre abrégé: Acta Otolaryngol
Pays: England
ID NLM: 0370354

Informations de publication

Date de publication:
Jun 2021
Historique:
pubmed: 6 5 2021
medline: 30 11 2021
entrez: 5 5 2021
Statut: ppublish

Résumé

Numerous techniques for closure of the anterior skull base in cancer patients have a high success rate but management of failure is poorly documented. To standardize the post-operative follow-up after reconstruction surgery of the anterior skull base after removal for sinonasal carcinoma. Retrospective review of failure of anterior skull base reconstruction between 2005 and 2018 in a multicenter setting. Twenty four patients were included. Reconstruction failure was detected by a cerebrospinal (CSF) leak in 79.2%, by an infectious complication without CSF leak (i.e. meningitis) in 12.5%, and in 8.3% by extensive pneumocephalus. Failure was observed during the first week after surgery in 75% of patients, in the second week in 21%, and in 4% after day 15. The delay in discovery of the failure was associated with multilayer reconstruction ( After carcinologic resection of the anterior skull base, monitoring should be systematic during the first postoperative week. Surgical management of failure is not always necessary.

Sections du résumé

BACKGROUND BACKGROUND
Numerous techniques for closure of the anterior skull base in cancer patients have a high success rate but management of failure is poorly documented.
OBJECTIVES OBJECTIVE
To standardize the post-operative follow-up after reconstruction surgery of the anterior skull base after removal for sinonasal carcinoma.
MATERIALS AND METHODS METHODS
Retrospective review of failure of anterior skull base reconstruction between 2005 and 2018 in a multicenter setting.
RESULTS RESULTS
Twenty four patients were included. Reconstruction failure was detected by a cerebrospinal (CSF) leak in 79.2%, by an infectious complication without CSF leak (i.e. meningitis) in 12.5%, and in 8.3% by extensive pneumocephalus. Failure was observed during the first week after surgery in 75% of patients, in the second week in 21%, and in 4% after day 15. The delay in discovery of the failure was associated with multilayer reconstruction (
CONCLUSION AND SIGNIFICANCE CONCLUSIONS
After carcinologic resection of the anterior skull base, monitoring should be systematic during the first postoperative week. Surgical management of failure is not always necessary.

Identifiants

pubmed: 33947299
doi: 10.1080/00016489.2021.1914858
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

630-634

Auteurs

Nicolas Saroul (N)

Otolaryngology Head and Neck Surgery Department, CHU de Clermont-Ferrand, Clermont-Ferrand, France.

Cécile Rumeau (C)

Otolaryngology Head and Neck Surgery Department, CHU de Nancy, Vandoeuvre les Nancy, France.

Benjamin Verillaud (B)

Otolaryngology Head and Neck Surgery Department, Hôpital Lariboisière, AP-HP, Paris, France.

Vincent Patron (V)

Otolaryngology Head and Neck Surgery Department, CHU de Caen, Caen, France.

Christian Righini (C)

Otolaryngology Head and Neck Surgery Department, CHU de Grenoble, Grenoble, France.

Guillaume De Bonnecaze (G)

Otolaryngology Head and Neck Surgery Department, CHU de Toulouse, Toulouse, France.

Clémentine Daveau (C)

Otolaryngology Head and Neck Surgery Department Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.

Geoffrey Mortuaire (G)

Otolaryngology Head and Neck Surgery Department, CHU de Lille, Lille, France.

Thierry Mom (T)

Otolaryngology Head and Neck Surgery Department, CHU de Clermont-Ferrand, Clermont-Ferrand, France.

Laurent Gilain (L)

Otolaryngology Head and Neck Surgery Department, CHU de Clermont-Ferrand, Clermont-Ferrand, France.

Bruno Pereira (B)

Biostatistics Department (DRCI), CHU de Clermont-Ferrand, Clermont-Ferrand, France.

Laura Montrieul (L)

Otolaryngology Head and Neck Surgery Department, CHU de Clermont-Ferrand, Clermont-Ferrand, France.

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