Drug-Drug Interaction Between Oxycodone and Diazepam by a Combined
MD simulations
Oxycodone
diazepam
drug−drug interaction (DDI)
molecular docking
pharmacodynamic-DDI
pharmacokinetic-DDI
physiologically based pharmacokinetics (PBPK)
Journal
ACS chemical neuroscience
ISSN: 1948-7193
Titre abrégé: ACS Chem Neurosci
Pays: United States
ID NLM: 101525337
Informations de publication
Date de publication:
19 05 2021
19 05 2021
Historique:
pubmed:
6
5
2021
medline:
22
6
2021
entrez:
5
5
2021
Statut:
ppublish
Résumé
Opioids and benzodiazepines have complex drug-drug interactions (DDIs), which serve as an important source of adverse drug effects. In this work, we predicted the DDI between oxycodone (OXY) and diazepam (DZP) in the human body by applying
Identifiants
pubmed: 33950681
doi: 10.1021/acschemneuro.0c00810
pmc: PMC8374491
mid: NIHMS1727204
doi:
Substances chimiques
Pharmaceutical Preparations
0
Oxycodone
CD35PMG570
Diazepam
Q3JTX2Q7TU
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1777-1790Subventions
Organisme : NIDA NIH HHS
ID : P30 DA035778
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA052329
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM079383
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001857
Pays : United States
Références
J Pharm Biomed Anal. 2017 Sep 10;144:129-137
pubmed: 27692933
Clin Pharmacol Ther. 2006 May;79(5):461-79
pubmed: 16678548
J Chem Theory Comput. 2015 Aug 11;11(8):3696-713
pubmed: 26574453
Toxicology. 1997 Feb 14;117(1):13-23
pubmed: 9020195
Drug Alcohol Depend. 1981 Nov;8(3):189-99
pubmed: 7327083
J Comput Chem. 2008 Aug;29(11):1859-65
pubmed: 18351591
Biochem J. 1999 Jun 15;340 ( Pt 3):845-53
pubmed: 10359672
Adv Neurol. 1983;34:487-91
pubmed: 6131586
Handb Exp Pharmacol. 2008;(182):335-60
pubmed: 18175099
J Pain Symptom Manage. 1993 Feb;8(2):63-7
pubmed: 8492004
Anesthesiology. 2007 May;106(5):1063-4; author reply 1064-5
pubmed: 17457147
Psychopharmacology (Berl). 1981;73(4):381-3
pubmed: 6789361
Pharmacol Res Perspect. 2016 Jan 22;4(1):e00210
pubmed: 26977300
J Comput Chem. 2004 Jul 15;25(9):1157-74
pubmed: 15116359
J Forensic Sci. 2005 Jan;50(1):192-5
pubmed: 15831018
Drug Metab Dispos. 2004 Apr;32(4):447-54
pubmed: 15039299
J Pharm Sci. 1981 Oct;70(10):1104-7
pubmed: 6117653
Drugs R D. 2019 Sep;19(3):297-305
pubmed: 31482303
Clin Pharmacokinet. 2005;44(3):279-304
pubmed: 15762770
Clin Pharmacokinet. 2016 Nov;55(11):1435-1445
pubmed: 27225997
Chem Biol Interact. 2004 Apr 15;147(3):319-29
pubmed: 15135087
J Med Chem. 2004 Mar 25;47(7):1739-49
pubmed: 15027865
J Opioid Manag. 2012 May-Jun;8(3):161-6
pubmed: 22798176
J Pharmacol Exp Ther. 2004 Feb;308(2):547-54
pubmed: 14600248
Biophys J. 2004 Jan;86(1 Pt 1):67-74
pubmed: 14695250
JAMA. 1978 Oct 20;240(17):1872-4
pubmed: 357765
Am J Prev Med. 2015 Oct;49(4):493-501
pubmed: 26143953
ACS Chem Neurosci. 2014 Apr 16;5(4):253-60
pubmed: 24552479
Phys Chem Chem Phys. 2019 May 15;21(19):10135-10145
pubmed: 31062799
J Chem Theory Comput. 2013 Sep 10;9(9):3878-88
pubmed: 26592383
Drug Alcohol Depend. 2014 May 1;138:118-23
pubmed: 24629782
Clin Transl Oncol. 2007 May;9(5):298-307
pubmed: 17525040
Drug Metab Dispos. 2001 Dec;29(12):1644-51
pubmed: 11717184
J Clin Invest. 1975 Feb;55(2):347-59
pubmed: 1127104
Curr Med Res Opin. 2008 Jan;24(1):175-92
pubmed: 18039433
J Chem Theory Comput. 2012 May 8;8(5):1542-1555
pubmed: 22582031
J Chem Inf Model. 2012 May 25;52(5):1199-212
pubmed: 22497310
Drug Metab Dispos. 1997 Feb;25(2):133-9
pubmed: 9029042
Clin Pharmacokinet. 2014 Jan;53(1):73-87
pubmed: 23881596
Eur J Pharm Sci. 2014 Jun 16;57:300-21
pubmed: 24060672
Drug Metab Dispos. 2000 Apr;28(4):467-74
pubmed: 10725316
Clin Pharmacol Ther. 1992 Aug;52(2):139-50
pubmed: 1505149
Aust N Z J Obstet Gynaecol. 2007 Jun;47(3):181-5
pubmed: 17550483
Drug Alcohol Depend. 2012 Sep 1;125(1-2):8-18
pubmed: 22857878
Ther Drug Monit. 2004 Aug;26(4):380-5
pubmed: 15257067
J Chem Inf Model. 2011 Jan 24;51(1):69-82
pubmed: 21117705
Clin Pharmacokinet. 1978 Jan-Feb;3(1):72-91
pubmed: 346285
CPT Pharmacometrics Syst Pharmacol. 2014 Dec 17;3:e152
pubmed: 25518025
Xenobiotica. 2010 Jan;40(1):1-8
pubmed: 19905875
Chem Rev. 2019 Aug 28;119(16):9478-9508
pubmed: 31244000
J Mol Graph Model. 2006 Oct;25(2):247-60
pubmed: 16458552
ACS Omega. 2020 Feb 25;5(9):4611-4619
pubmed: 32175507
J Med Chem. 2005 Jun 16;48(12):4040-8
pubmed: 15943477
Forensic Sci Int. 2006 Oct 16;162(1-3):80-6
pubmed: 16879940
Anesth Analg. 2001 Aug;93(2):354-8 , 3rd contents page
pubmed: 11473860
J Biomol Screen. 2009 Sep;14(8):913-23
pubmed: 19675314
Clin Pharmacokinet. 2017 Apr;56(4):409-420
pubmed: 27599706
J Phys Chem B. 2013 Jul 18;117(28):8408-21
pubmed: 23789789
J Am Chem Soc. 2015 Feb 25;137(7):2695-703
pubmed: 25625324
Natl Vital Stat Rep. 2016 Dec;65(10):1-15
pubmed: 27996932
Br J Clin Pharmacol. 2011 Dec;72(6):985-9
pubmed: 21671987