N-Acyltriazinedione; a Novel Acylating Reagent Synthesized from a Triazinone-Type Condensing Reagent.
O–N acyl rearrangement
acylating reagent
triazinedione
Journal
Chemical & pharmaceutical bulletin
ISSN: 1347-5223
Titre abrégé: Chem Pharm Bull (Tokyo)
Pays: Japan
ID NLM: 0377775
Informations de publication
Date de publication:
2021
2021
Historique:
entrez:
6
5
2021
pubmed:
7
5
2021
medline:
28
7
2021
Statut:
ppublish
Résumé
In this paper, we report the synthesis of N-acyltriazinedione via the unexpected O-N acyl rearrangement of acyloxytriazinone and its utility as an acylating reagent. N-Acyltriazinedione can be isolated by silica gel column chromatography and reacts with amines in the absence of any base to give the corresponding amides in good yields.
Identifiants
pubmed: 33952859
doi: 10.1248/cpb.c20-00952
doi:
Substances chimiques
Indicators and Reagents
0
Triazines
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM