MicroRNA‑101 inhibits renal tubular epithelial‑to‑mesenchymal transition by targeting TGF‑β1 type I receptor.
TGF‑β1 type I receptor
microRNA‑101
renal interstitial fibrosis
tubular epithelial‑to‑mesenchymal transition
Journal
International journal of molecular medicine
ISSN: 1791-244X
Titre abrégé: Int J Mol Med
Pays: Greece
ID NLM: 9810955
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
11
07
2020
accepted:
30
03
2021
entrez:
6
5
2021
pubmed:
7
5
2021
medline:
19
11
2021
Statut:
ppublish
Résumé
MicroRNAs (miRNAs/miRs) are key regulators of renal interstitial fibrosis (RIF). The present study was designed to identify miRNAs associated with the development of RIF, and to explore the ability of these identified miRNAs to modulate the renal tubular epithelial‑to‑mesenchymal transition (EMT) process. To this end, miRNAs that were differentially expressed between normal and fibrotic kidneys in a rat model of mercury chloride (HgCl
Identifiants
pubmed: 33955520
doi: 10.3892/ijmm.2021.4952
pii: 119
pmc: PMC8099196
doi:
pii:
Substances chimiques
MIRN101 microRNA, human
0
MIRN101 microRNA, rat
0
MicroRNAs
0
Receptor, Transforming Growth Factor-beta Type I
EC 2.7.11.30
TGFBR1 protein, human
EC 2.7.11.30
Tgfbr1 protein, rat
EC 2.7.11.30
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
Cancer Res. 2015 May 1;75(9):1859-67
pubmed: 25769721
Nat Rev Nephrol. 2015 Oct;11(10):565
pubmed: 26241016
Cell Res. 2009 Feb;19(2):156-72
pubmed: 19153598
Curr Opin Nephrol Hypertens. 2012 May;21(3):289-300
pubmed: 22449945
Oncotarget. 2016 Jul 26;7(30):47760-47776
pubmed: 27351287
J Am Soc Nephrol. 2006 Nov;17(11):2992-8
pubmed: 17035610
J Ethnopharmacol. 2010 Feb 17;127(3):631-40
pubmed: 20015471
Methods. 2001 Dec;25(4):402-8
pubmed: 11846609
Mol Ther. 2019 May 8;27(5):1051-1065
pubmed: 30853453
Hum Exp Toxicol. 2020 Dec;39(12):1628-1638
pubmed: 32633566
Int J Nephrol Renovasc Dis. 2013 Sep 25;6:169-79
pubmed: 24109192
Front Biosci (Schol Ed). 2010 Jan 01;2:229-38
pubmed: 20036943
Chin J Integr Med. 2017 Aug;23(8):598-604
pubmed: 28197934
J Pathol. 2014 Sep;234(1):46-59
pubmed: 24817606
Panminerva Med. 2019 Jul 30;:
pubmed: 31362481
Nat Rev Nephrol. 2011 Oct 18;7(12):684-96
pubmed: 22009250
Cell Physiol Biochem. 2015;35(1):213-26
pubmed: 25591764
Anal Biochem. 1981 Mar 15;112(1):70-5
pubmed: 7258630
J Am Heart Assoc. 2019 Dec 3;8(23):e013112
pubmed: 31766975
Nephrol Dial Transplant. 2014 Feb;29 Suppl 1:i37-i45
pubmed: 24030832
Clin Sci (Lond). 2013 Feb;124(4):243-54
pubmed: 23126427
J Am Soc Nephrol. 2014 Jan;25(1):65-80
pubmed: 24158985
Dev Cell. 2006 Oct;11(4):441-50
pubmed: 17011485
Eur Respir J. 2007 May;29(5):976-85
pubmed: 17301095
Lab Anim. 1996 Oct;30(4):293-316
pubmed: 8938617
J Am Soc Nephrol. 2002 Jan;13(1):96-107
pubmed: 11752026
Nat Rev Genet. 2004 Jul;5(7):522-31
pubmed: 15211354
Annu Rev Biochem. 2010;79:351-79
pubmed: 20533884
Exp Ther Med. 2019 Mar;17(3):2310-2316
pubmed: 30867715
Cell Tissue Res. 2012 Jan;347(1):103-16
pubmed: 21845400
J Clin Invest. 2002 Aug;110(3):341-50
pubmed: 12163453
IUBMB Life. 2019 Feb;71(2):235-243
pubmed: 30549198
Circulation. 2012 Aug 14;126(7):840-50
pubmed: 22811578
Cell Physiol Biochem. 2017;42(6):2207-2219
pubmed: 28817807
Eur J Clin Invest. 2016 Mar;46(3):213-26
pubmed: 26707063
Stat Appl Genet Mol Biol. 2004;3:Article3
pubmed: 16646809
J Biol Chem. 2017 Oct 6;292(40):16420-16439
pubmed: 28726637
BMC Cell Biol. 2010 May 05;11:31
pubmed: 20441599
Clin Res Hepatol Gastroenterol. 2019 Oct;43(5):575-584
pubmed: 30857885
Eur Respir J. 2015 Jan;45(1):116-28
pubmed: 25186262
Bioinformatics. 2007 May 1;23(9):1141-7
pubmed: 17350973
Clin Sci (Lond). 2015 Dec;129(12):1237-49
pubmed: 26415649