Organoids of the Female Reproductive Tract: Innovative Tools to Study Desired to Unwelcome Processes.

cancer modeling gynecology organoids reproduction women’s health

Journal

Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250

Informations de publication

Date de publication:
2021
Historique:
received: 30 01 2021
accepted: 22 03 2021
entrez: 7 5 2021
pubmed: 8 5 2021
medline: 8 5 2021
Statut: epublish

Résumé

The pelviperineal organs of the female reproductive tract form an essential cornerstone of human procreation. The system comprises the ectodermal external genitalia, the Müllerian upper-vaginal, cervical, endometrial and oviductal derivatives, and the endodermal ovaries. Each of these organs presents with a unique course of biological development as well as of malignant degeneration. For many decades, various preclinical

Identifiants

pubmed: 33959613
doi: 10.3389/fcell.2021.661472
pmc: PMC8093793
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

661472

Informations de copyright

Copyright © 2021 Heremans, Jan, Timmerman and Vankelecom.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Ruben Heremans (R)

Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium.
Cluster Woman and Child, Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Department of Obstetrics and Gynecology, University Hospitals, KU Leuven, Leuven, Belgium.

Ziga Jan (Z)

Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium.
Cluster Woman and Child, Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Department of Gynecology, Klinikum Klagenfurt, Klagenfurt, Austria.

Dirk Timmerman (D)

Cluster Woman and Child, Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Department of Obstetrics and Gynecology, University Hospitals, KU Leuven, Leuven, Belgium.

Hugo Vankelecom (H)

Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium.

Classifications MeSH