Hugo Vankelecom

Affiliations

Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, KU Leuven (University of Leuven); hugo.vankelecom@kuleuven.be.

Publications (42)

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology.

Journal of visualized experiments : JoVE

Avec: Emma Laporte , Charlotte Nys , Hugo Vankelecom

Decoding the activated stem cell phenotype of the neonatally maturing pituitary.

eLife

Avec: Emma Laporte , Florian Hermans , Silke De Vriendt , Annelies Vennekens , Diether Lambrechts , Charlotte Nys , Benoit Cox , Hugo Vankelecom

Fluorescence Imaging of 3D Cell Models with Subcellular Resolution.

Bio-protocol

Avec: Indra Van Zundert , Nina Maenhoudt , Silke De Vriendt , Hugo Vankelecom , Beatrice Fortuni , Susana Rocha

Prednisone vs Placebo and Live Birth in Patients With Recurrent Implantation Failure Undergoing In Vitro Fertilization: A Randomized Clinical Trial.

JAMA

Avec: Yun Sun , Linlin Cui , Yao Lu , Jichun Tan , Xi Dong , Tianxiang Ni , Junhao Yan , Yichun Guan , Guimin Hao , Jia-Yin Liu , Bo Zhang , Daimin Wei , Yan Hong , Yaqiong He , Jia Qi , Bing Xu , Juanjuan Lu , Qian Zhang , Shanshan Zhao , Xiaowei Ji , Xiaofang Du , Jie Zhang , Jinyong Liu , Jing Wang , Yingqin Huang , Dongmei Huang , Yanzhi Du , Hugo Vankelecom , Heping Zhang , Zi-Jiang Chen

Developing Organoids from Ovarian Cancer as Experimental and Preclinical Models.

Stem cell reports

Avec: Nina Maenhoudt , Charlotte Defraye , Matteo Boretto , Ziga Jan , Ruben Heremans , Bram Boeckx , Florian Hermans , Ingrid Arijs , Benoit Cox , Els Van Nieuwenhuysen , Ignace Vergote , Anne-Sophie Van Rompuy , Diether Lambrechts , Dirk Timmerman , Hugo Vankelecom

Organoids can be established reliably from cryopreserved biopsy catheter-derived endometrial tissue of infertile women.

Reproductive biomedicine online

Avec: Bich Ngoc Bui , Matteo Boretto , Hiroto Kobayashi , Marliek van Hoesel , Gaby S Steba , Nienke van Hoogenhuijze , Frank J M Broekmans , Hugo Vankelecom , Helen L Torrance

Coordination of germ layer lineage choice by TET1 during primed pluripotency.

Genes & development

Avec: Xinlong Luo , Bernard K van der Veer , Lei Sun , Michela Bartoccetti , Matteo Boretto , Hugo Vankelecom , Rita Khoueiry , Kian Peng Koh

Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening.

Nature cell biology

Avec: Matteo Boretto , Nina Maenhoudt , Xinlong Luo , Aurélie Hennes , Bram Boeckx , Bich Bui , Ruben Heremans , Lisa Perneel , Hiroto Kobayashi , Indra Van Zundert , Hilde Brems , Benoit Cox , Marc Ferrante , Hiroshi Uji-I , Kian Peng Koh , Thomas D'Hooghe , Arne Vanhie , Ignace Vergote , Christel Meuleman , Carla Tomassetti , Diether Lambrechts , Joris Vriens , Dirk Timmerman , Hugo Vankelecom

Organoids of the Female Reproductive Tract: Innovative Tools to Study Desired to Unwelcome Processes.

Frontiers in cell and developmental biology

Avec: Ruben Heremans , Ziga Jan , Dirk Timmerman , Hugo Vankelecom

Organoids from human tooth showing epithelial stemness phenotype and differentiation potential.

Cellular and molecular life sciences : CMLS

Avec: Lara Hemeryck , Florian Hermans , Joel Chappell , Hiroto Kobayashi , Diether Lambrechts , Ivo Lambrichts , Annelies Bronckaers , Hugo Vankelecom

iTRAQ-based Proteomic Analysis Unveils ACSL4 as a Novel Potential Regulator of Human Endometrial Receptivity.

Endocrinology

Avec: Shuanggang Hu , Zhe Sun , Boyu Li , Hanting Zhao , Yuan Wang , Guangxin Yao , Xinyu Li , Xuejiao Bian , Tin Chiu Li , Hugo Vankelecom , Yun Sun

Organoids from pituitary as a novel research model toward pituitary stem cell exploration.

The Journal of endocrinology

Avec: Benoit Cox , Emma Laporte , Annelies Vennekens , Hiroto Kobayashi , Charlotte Nys , Indra Van Zundert , Hiroshi Uji-I , Alizée Vercauteren Drubbel , Benjamin Beck , Heleen Roose , Matteo Boretto , Hugo Vankelecom

Inhibition of Notch signaling attenuates pituitary adenoma growth in Nude mice.

Endocrine-related cancer

Avec: Lautaro Zubeldía-Brenner , Catalina De Winne , Sofía Perrone , Santiago A Rodríguez-Seguí , Christophe Willems , Ana María Ornstein , Isabel Lacau-Mengido , Hugo Vankelecom , Carolina Cristina , Damasia Becu-Villalobos

The ellagic acid metabolites urolithin A and B differentially affect growth, adhesion, motility, and invasion of endometriotic cells in vitro.

Human reproduction (Oxford, England)

Avec: Barbara Mc Cormack , N Maenhoudt , V Fincke , A Stejskalova , B Greve , L Kiesel , G F Meresman , H Vankelecom , M Götte , R I Barañao

In vitro modelling of the physiological and diseased female reproductive system.

Acta biomaterialia

Avec: Anna Stejskalová , Hugo Vankelecom , Marina Sourouni , Magdalene Y Ho , Martin Götte , Benjamin D Almquist

Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Annelies Vennekens , Emma Laporte , Florian Hermans , Benoit Cox , Elodie Modave , Adrian Janiszewski , Charlotte Nys , Hiroto Kobayashi , Bert Malengier-Devlies , Joel Chappell , Patrick Matthys , Marie-Isabelle Garcia , Vincent Pasque , Diether Lambrechts , Hugo Vankelecom

Exploring stem cell biology in pituitary tumors and derived organoids.

Endocrine-related cancer

Avec: Charlotte Nys , Yu-Lun Lee , Heleen Roose , Freya Mertens , Ellen De Pauw , Hiroto Kobayashi , Raf Sciot , Marie Bex , Georges Versyck , Steven De Vleeschouwer , Johannes Van Loon , Emma Laporte , Hugo Vankelecom

Endometriosis organoids: prospects and challenges.

Reproductive biomedicine online

Avec: Fereshteh Esfandiari , Nahid Mansouri , Maryam Shahhoseini , Heidar Heidari Khoei , Gelareh Mikaeeli , Hugo Vankelecom , Hossein Baharvand

Establishment of inclusive single-cell transcriptome atlases from mouse and human tooth as powerful resource for dental research.

Frontiers in cell and developmental biology

Avec: Florian Hermans , Celine Bueds , Lara Hemeryck , Ivo Lambrichts , Annelies Bronckaers , Hugo Vankelecom

Local glucose elevation activates pyroptosis via NLRP3 inflammasome in ovarian granulosa cells of overweight patients.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Rui Xu , Hanting Zhao , Jia Qi , Guangxin Yao , Yaqiong He , Yao Lu , Qinling Zhu , Yuan Wang , Ying Ding , Zhenyi Zhu , Xinyu Li , Hugo Vankelecom , Yun Sun

Organoids from mouse molar and incisor as new tools to study tooth-specific biology and development.

Stem cell reports

Avec: Florian Hermans , Lara Hemeryck , Celine Bueds , Marc Torres Pereiro , Steffie Hasevoets , Hiroto Kobayashi , Diether Lambrechts , Ivo Lambrichts , Annelies Bronckaers , Hugo Vankelecom

Locationally activated PRP via an injectable dual-network hydrogel for endometrial regeneration.

Biomaterials

Avec: Jia Qi , Xiaoxiao Li , Yumeng Cao , Yijing Long , Junliang Lai , Yejie Yao , Yiwen Meng , Yuan Wang , Xiao-Dong Chen , Hugo Vankelecom , Xuejiao Bian , Wenguo Cui , Yun Sun

Functional expression of the mechanosensitive PIEZO1 channel in primary endometrial epithelial cells and endometrial organoids.

Scientific reports

Avec: Aurélie Hennes , Katharina Held , Matteo Boretto , Katrien De Clercq , Charlotte Van den Eynde , Arne Vanhie , Nele Van Ranst , Melissa Benoit , Catherine Luyten , Karen Peeraer , Carla Tomassetti , Christel Meuleman , Thomas Voets , Hugo Vankelecom , Joris Vriens

Traumatic brain injury and resultant pituitary dysfunction: insights from experimental animal models.

Pituitary

Avec: Annelies Vennekens , Hugo Vankelecom

Skin Epidermis and Adnexa Regrowth Induced by Treatment With Artificial Dermal Template After Full-Thickness Skin Wound.

The international journal of lower extremity wounds

Avec: Binghui Li , Hang Xue , Xiaobo Zhao , Yuxiong Weng , Gongchi Li , Kun Wang , Pan Zhou , Youtong Wu , Hugo Vankelecom , Jianghai Chen

Decoding the endometrial niche of Asherman's Syndrome at single-cell resolution.

Nature communications

Avec: Xavier Santamaria , Beatriz Roson , Raul Perez-Moraga , Nandakumar Venkatesan , Maria Pardo-Figuerez , Javier Gonzalez-Fernandez , Jaime Llera-Oyola , Estefania Fernández , Inmaculada Moreno , Andres Salumets , Hugo Vankelecom , Felipe Vilella , Carlos Simon

ENDOCELL-Seud: a Delphi protocol to harmonise methods in endometrial cell culturing.

Reproduction & fertility

Avec: Andrea Romano , Sun-Wei Guo , Jan Brosens , Asgerally Fazlebas , Caroline E Gargett , Stefan Giselbrecht , Martin Gotte , Linda Griffith , Hugh S Taylor , Robert N Taylor , Hugo Vankelecom , Charles Chapron , Xiao-Hong Chang , Khaleque N Khan , Paola Vigano'

Modeling Endometrium Biology and Disease.

Journal of personalized medicine

Avec: Nina Maenhoudt , Amber De Moor , Hugo Vankelecom

Matrix scaffolds for endometrium-derived organoid models.

Frontiers in endocrinology

Avec: Silke De Vriendt , Celia Mesias Casares , Susana Rocha , Hugo Vankelecom

Ovarian ferroptosis induced by androgen is involved in pathogenesis of PCOS.

Human reproduction open

Avec: Xinyu Li , Yunying Lin , Xiaoyue Cheng , Guangxin Yao , Jufang Yao , Shuanggang Hu , Qinling Zhu , Yuan Wang , Ying Ding , Yao Lu , Jia Qi , Hanting Zhao , Xuejiao Bian , Yanzhi Du , Kang Sun , Hugo Vankelecom , Yun Sun

Pituitary Remodeling Throughout Life: Are Resident Stem Cells Involved?

Frontiers in endocrinology

Avec: Emma Laporte , Annelies Vennekens , Hugo Vankelecom

Protocol for establishing organoids from human ovarian cancer biopsies.

STAR protocols

Avec: Nina Maenhoudt , Hugo Vankelecom

Pituitary disease and recovery: How are stem cells involved?

Molecular and cellular endocrinology

Avec: Charlotte Nys , Hugo Vankelecom

Murine Endometrial Organoids to Model

Frontiers in cellular and infection microbiology

Avec: R Clayton Bishop , Matteo Boretto , Melanie R Rutkowski , Hugo Vankelecom , Isabelle Derré

Transnasal transsphenoidal pituitary surgery in a large tertiary hospital, a retrospective study.

Acta chirurgica Belgica

Avec: Charlotte Nys , Georges Versyck , Eveleen Buelens , Koen Engelborghs , Erwin Cornips , Heddy Van Leeuwen-Wintjens , Hugo Vankelecom , Frank Weyns , Diederik Peuskens

Intertwined Signaling Pathways Governing Tooth Development: A Give-and-Take Between Canonical Wnt and Shh.

Frontiers in cell and developmental biology

Avec: Florian Hermans , Lara Hemeryck , Ivo Lambrichts , Annelies Bronckaers , Hugo Vankelecom

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy.

Journal of visualized experiments : JoVE

Avec: Lara Hemeryck , Ivo Lambrichts , Annelies Bronckaers , Hugo Vankelecom

Human blastoids model blastocyst development and implantation.

Nature

Avec: Harunobu Kagawa , Alok Javali , Heidar Heidari Khoei , Theresa Maria Sommer , Giovanni Sestini , Maria Novatchkova , Yvonne Scholte Op Reimer , Gaël Castel , Alexandre Bruneau , Nina Maenhoudt , Jenna Lammers , Sophie Loubersac , Thomas Freour , Hugo Vankelecom , Laurent David , Nicolas Rivron

Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury.

Frontiers in endocrinology

Avec: Emma Laporte , Silke De Vriendt , Julie Hoekx , Hugo Vankelecom

Protease secretions by the invading blastocyst induce calcium oscillations in endometrial epithelial cells via the protease-activated receptor 2.

Reproductive biology and endocrinology : RB&E

Avec: Aurélie Hennes , Johanna Devroe , Katrien De Clercq , Martina Ciprietti , Katharina Held , Katrien Luyten , Nele Van Ranst , Nina Maenhoudt , Karen Peeraer , Hugo Vankelecom , Thomas Voets , Joris Vriens

Organoid models of the pituitary gland in health and disease.

Frontiers in endocrinology

Avec: Emma Laporte , Hugo Vankelecom

From Pluripotent Stem Cells to Organoids and Bioprinting: Recent Advances in Dental Epithelium and Ameloblast Models to Study Tooth Biology and Regeneration.

Stem cell reviews and reports

Avec: Florian Hermans , Steffie Hasevoets , Hugo Vankelecom , Annelies Bronckaers , Ivo Lambrichts

Réseau de co-auteurs

Emma Laporte 8 collaborations

Florian Hermans 8 collaborations

Charlotte Nys 7 collaborations

Nina Maenhoudt 7 collaborations

Matteo Boretto 7 collaborations

Hiroto Kobayashi 7 collaborations

Diether Lambrechts 6 collaborations

Ivo Lambrichts 6 collaborations

Annelies Bronckaers 6 collaborations

Annelies Vennekens 5 collaborations

Benoit Cox 5 collaborations

Yun Sun 5 collaborations

Lara Hemeryck 5 collaborations

Silke De Vriendt 4 collaborations

Jia Qi 4 collaborations

Yuan Wang 4 collaborations

Indra Van Zundert 3 collaborations

Yao Lu 3 collaborations

Ruben Heremans 3 collaborations

Dirk Timmerman 3 collaborations

Aurélie Hennes 3 collaborations

Joris Vriens 3 collaborations

Hanting Zhao 3 collaborations

Guangxin Yao 3 collaborations

Xinyu Li 3 collaborations

Xuejiao Bian 3 collaborations

Susana Rocha 2 collaborations

Yaqiong He 2 collaborations

Yanzhi Du 2 collaborations

Ziga Jan 2 collaborations

Bram Boeckx 2 collaborations

Ignace Vergote 2 collaborations

Xinlong Luo 2 collaborations

Kian Peng Koh 2 collaborations

Hiroshi Uji-I 2 collaborations

Arne Vanhie 2 collaborations

Christel Meuleman 2 collaborations

Carla Tomassetti 2 collaborations

Joel Chappell 2 collaborations

Shuanggang Hu 2 collaborations

Heleen Roose 2 collaborations

Georges Versyck 2 collaborations

Heidar Heidari Khoei 2 collaborations

Celine Bueds 2 collaborations

Qinling Zhu 2 collaborations

Ying Ding 2 collaborations

Steffie Hasevoets 2 collaborations

Katharina Held 2 collaborations

Katrien De Clercq 2 collaborations

Nele Van Ranst 2 collaborations

Karen Peeraer 2 collaborations

Thomas Voets 2 collaborations

Beatrice Fortuni 1 collaboration

Linlin Cui 1 collaboration

Jichun Tan 1 collaboration

Xi Dong 1 collaboration

Tianxiang Ni 1 collaboration

Junhao Yan 1 collaboration

Yichun Guan 1 collaboration

Guimin Hao 1 collaboration

Jia-Yin Liu 1 collaboration

Bo Zhang 1 collaboration

Daimin Wei 1 collaboration

Yan Hong 1 collaboration

Bing Xu 1 collaboration

Juanjuan Lu 1 collaboration

Qian Zhang 1 collaboration

Shanshan Zhao 1 collaboration

Xiaowei Ji 1 collaboration

Xiaofang Du 1 collaboration

Jie Zhang 1 collaboration

Jinyong Liu 1 collaboration

Jing Wang 1 collaboration

Yingqin Huang 1 collaboration

Dongmei Huang 1 collaboration

Heping Zhang 1 collaboration

Zi-Jiang Chen 1 collaboration

Charlotte Defraye 1 collaboration

Ingrid Arijs 1 collaboration

Els Van Nieuwenhuysen 1 collaboration

Anne-Sophie Van Rompuy 1 collaboration

Bich Ngoc Bui 1 collaboration

Marliek van Hoesel 1 collaboration

Gaby S Steba 1 collaboration

Nienke van Hoogenhuijze 1 collaboration

Frank J M Broekmans 1 collaboration

Helen L Torrance 1 collaboration

Bernard K van der Veer 1 collaboration

Lei Sun 1 collaboration

Michela Bartoccetti 1 collaboration

Rita Khoueiry 1 collaboration

Bich Bui 1 collaboration

Lisa Perneel 1 collaboration

Hilde Brems 1 collaboration

Marc Ferrante 1 collaboration

Thomas D'Hooghe 1 collaboration

Zhe Sun 1 collaboration

Boyu Li 1 collaboration

Tin Chiu Li 1 collaboration

Alizée Vercauteren Drubbel 1 collaboration

Benjamin Beck 1 collaboration

Lautaro Zubeldía-Brenner 1 collaboration

Catalina De Winne 1 collaboration

Sofía Perrone 1 collaboration

Santiago A Rodríguez-Seguí 1 collaboration

Christophe Willems 1 collaboration

Ana María Ornstein 1 collaboration

Isabel Lacau-Mengido 1 collaboration

Carolina Cristina 1 collaboration

Damasia Becu-Villalobos 1 collaboration

Barbara Mc Cormack 1 collaboration

N Maenhoudt 1 collaboration

V Fincke 1 collaboration

A Stejskalova 1 collaboration

B Greve 1 collaboration

L Kiesel 1 collaboration

G F Meresman 1 collaboration

H Vankelecom 1 collaboration

M Götte 1 collaboration

R I Barañao 1 collaboration

Anna Stejskalová 1 collaboration

Marina Sourouni 1 collaboration

Magdalene Y Ho 1 collaboration

Martin Götte 1 collaboration

Benjamin D Almquist 1 collaboration

Elodie Modave 1 collaboration

Adrian Janiszewski 1 collaboration

Bert Malengier-Devlies 1 collaboration

Patrick Matthys 1 collaboration

Marie-Isabelle Garcia 1 collaboration

Vincent Pasque 1 collaboration

Yu-Lun Lee 1 collaboration

Freya Mertens 1 collaboration

Ellen De Pauw 1 collaboration

Raf Sciot 1 collaboration

Marie Bex 1 collaboration

Steven De Vleeschouwer 1 collaboration

Johannes Van Loon 1 collaboration

Fereshteh Esfandiari 1 collaboration

Nahid Mansouri 1 collaboration

Maryam Shahhoseini 1 collaboration

Gelareh Mikaeeli 1 collaboration

Hossein Baharvand 1 collaboration

Rui Xu 1 collaboration

Zhenyi Zhu 1 collaboration

Marc Torres Pereiro 1 collaboration

Xiaoxiao Li 1 collaboration

Yumeng Cao 1 collaboration

Yijing Long 1 collaboration

Junliang Lai 1 collaboration

Yejie Yao 1 collaboration

Yiwen Meng 1 collaboration

Xiao-Dong Chen 1 collaboration

Wenguo Cui 1 collaboration

Charlotte Van den Eynde 1 collaboration

Melissa Benoit 1 collaboration

Catherine Luyten 1 collaboration

Binghui Li 1 collaboration

Hang Xue 1 collaboration

Xiaobo Zhao 1 collaboration

Yuxiong Weng 1 collaboration

Gongchi Li 1 collaboration

Kun Wang 1 collaboration

Pan Zhou 1 collaboration

Youtong Wu 1 collaboration

Jianghai Chen 1 collaboration

Xavier Santamaria 1 collaboration

Beatriz Roson 1 collaboration

Raul Perez-Moraga 1 collaboration

Nandakumar Venkatesan 1 collaboration

Maria Pardo-Figuerez 1 collaboration

Javier Gonzalez-Fernandez 1 collaboration

Jaime Llera-Oyola 1 collaboration

Estefania Fernández 1 collaboration

Inmaculada Moreno 1 collaboration

Andres Salumets 1 collaboration

Felipe Vilella 1 collaboration

Carlos Simon 1 collaboration

Andrea Romano 1 collaboration

Sun-Wei Guo 1 collaboration

Jan Brosens 1 collaboration

Asgerally Fazlebas 1 collaboration

Caroline E Gargett 1 collaboration

Stefan Giselbrecht 1 collaboration

Martin Gotte 1 collaboration

Linda Griffith 1 collaboration

Hugh S Taylor 1 collaboration

Robert N Taylor 1 collaboration

Charles Chapron 1 collaboration

Xiao-Hong Chang 1 collaboration

Khaleque N Khan 1 collaboration

Paola Vigano' 1 collaboration

Amber De Moor 1 collaboration

Celia Mesias Casares 1 collaboration

Yunying Lin 1 collaboration

Xiaoyue Cheng 1 collaboration

Jufang Yao 1 collaboration

Kang Sun 1 collaboration

R Clayton Bishop 1 collaboration

Melanie R Rutkowski 1 collaboration

Isabelle Derré 1 collaboration

Eveleen Buelens 1 collaboration

Koen Engelborghs 1 collaboration

Erwin Cornips 1 collaboration

Heddy Van Leeuwen-Wintjens 1 collaboration

Frank Weyns 1 collaboration

Diederik Peuskens 1 collaboration

Harunobu Kagawa 1 collaboration

Alok Javali 1 collaboration

Theresa Maria Sommer 1 collaboration

Giovanni Sestini 1 collaboration

Maria Novatchkova 1 collaboration

Yvonne Scholte Op Reimer 1 collaboration

Gaël Castel 1 collaboration

Alexandre Bruneau 1 collaboration

Jenna Lammers 1 collaboration

Sophie Loubersac 1 collaboration

Thomas Freour 1 collaboration

Laurent David 1 collaboration

Nicolas Rivron 1 collaboration

Julie Hoekx 1 collaboration

Johanna Devroe 1 collaboration

Martina Ciprietti 1 collaboration

Katrien Luyten 1 collaboration