Organoid models of the pituitary gland in health and disease.

PitNETs organoids pituitary pituitary stem cells pluripotent stem cells

Journal

Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782

Informations de publication

Date de publication:
2023
Historique:
received: 02 06 2023
accepted: 20 07 2023
medline: 25 8 2023
pubmed: 24 8 2023
entrez: 24 8 2023
Statut: epublish

Résumé

The pituitary gland represents the hub of our endocrine system. Its cells produce specific hormones that direct multiple vital physiological processes such as body growth, fertility, and stress. The gland also contains a population of stem cells which are still enigmatic in phenotype and function. Appropriate research models are needed to advance our knowledge on pituitary (stem cell) biology. Over the last decade, 3D organoid models have been established, either derived from the pituitary stem cells or from pluripotent stem cells, covering both healthy and diseased conditions. Here, we summarize the state-of-the-art of pituitary-allied organoid models and discuss applications of these powerful

Identifiants

pubmed: 37614709
doi: 10.3389/fendo.2023.1233714
pmc: PMC10442803
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1233714

Informations de copyright

Copyright © 2023 Laporte and Vankelecom.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

J Endocrinol. 2019 Feb 1;240(2):287-308
pubmed: 30475227
Front Endocrinol (Lausanne). 2022 Jul 12;13:941166
pubmed: 35903276
Clin Cancer Res. 2016 Oct 15;22(20):5030-5042
pubmed: 27742789
J Clin Med. 2015 Jul 14;4(7):1480-97
pubmed: 26239687
Front Oncol. 2022 May 26;12:916982
pubmed: 35712496
Front Endocrinol (Lausanne). 2021 Jan 29;11:604519
pubmed: 33584539
Mol Cell Endocrinol. 2021 Apr 5;525:111176
pubmed: 33503464
Nat Cell Biol. 2019 Aug;21(8):1041-1051
pubmed: 31371824
J Dent Res. 2021 Feb;100(2):201-208
pubmed: 32881601
Drug Des Devel Ther. 2016 Jul 04;10:2155-65
pubmed: 27445462
Pathol Oncol Res. 2021 Apr 21;27:640676
pubmed: 34257605
Cell Rep. 2013 Dec 12;5(5):1387-402
pubmed: 24290755
Curr Opin Endocrinol Diabetes Obes. 2017 Aug;24(4):292-300
pubmed: 28520591
Hum Mol Genet. 2015 Feb 15;24(4):939-53
pubmed: 25315894
Pituitary. 2019 Jun;22(3):212-219
pubmed: 31020506
Nat Rev Endocrinol. 2011 May;7(5):257-66
pubmed: 21423242
Elife. 2021 Jan 05;10:
pubmed: 33399538
J Endocr Soc. 2019 Aug 26;3(11):1969-1978
pubmed: 31620667
Aging Cell. 2018 Dec;17(6):e12833
pubmed: 30168637
Elife. 2022 Jun 14;11:
pubmed: 35699412
Stem Cell Reports. 2016 Jun 14;6(6):858-872
pubmed: 27304916
Endocr Relat Cancer. 2015 Aug;22(4):481-504
pubmed: 25921430
J Endocr Soc. 2021 Mar 30;5(6):bvab055
pubmed: 34061117
Annu Rev Neurosci. 2001;24:327-55
pubmed: 11283314
Genes Dev. 2006 Oct 1;20(19):2739-53
pubmed: 17015435
Front Neuroendocrinol. 1999 Jan;20(1):71-95
pubmed: 9882537
J Vis Exp. 2019 Oct 4;(152):
pubmed: 31633678
Elife. 2021 Sep 06;10:
pubmed: 34487490
Cell Mol Life Sci. 2022 Dec 1;79(12):612
pubmed: 36451046
Stem Cells Dev. 2012 Mar 20;21(5):801-13
pubmed: 21970375
Neuroendocrinology. 2020;110(9-10):797-804
pubmed: 32126562
Endocrinology. 2005 Sep;146(9):3985-98
pubmed: 15932930
Acta Histochem Cytochem. 2013 Aug 29;46(4):121-7
pubmed: 24023396
Endocrinology. 1984 Jun;114(6):2107-13
pubmed: 6426937
J Vis Exp. 2016 Feb 18;(108):53637
pubmed: 26966916
Cell Mol Life Sci. 2021 Mar;78(5):2069-2079
pubmed: 33206204
Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):
pubmed: 34161279
Cell. 2016 Jun 16;165(7):1586-1597
pubmed: 27315476
Lancet. 2007 Apr 28;369(9571):1461-1470
pubmed: 17467517
N Engl J Med. 2020 Mar 5;382(10):937-950
pubmed: 32130815
J Exp Med. 2017 Mar 6;214(3):579-596
pubmed: 28232471
Pituitary. 2022 Apr;25(2):238-245
pubmed: 34773564
Front Endocrinol (Lausanne). 2023 Mar 02;14:1130465
pubmed: 36936140
Stem Cells Dev. 2022 May;31(9-10):239-249
pubmed: 35382563
Stem Cell Reports. 2020 Apr 14;14(4):717-729
pubmed: 32243841
Science. 2021 Feb 19;371(6531):839-846
pubmed: 33602855
Endocrinology. 2016 Feb;157(2):705-21
pubmed: 26653762
Endocrinology. 2012 Jul;153(7):3224-35
pubmed: 22518061
Front Endocrinol (Lausanne). 2017 Dec 04;8:339
pubmed: 29255445
J Vis Exp. 2022 Feb 25;(180):
pubmed: 35285833
Front Endocrinol (Lausanne). 2023 Jan 19;13:1025825
pubmed: 36743928
PLoS One. 2009;4(3):e4815
pubmed: 19283075
Gastroenterology. 2020 Oct;159(4):1564-1567
pubmed: 32474118
Endocr Relat Cancer. 2022 Jun 17;29(7):427-450
pubmed: 35521774
Nature. 2011 Nov 09;480(7375):57-62
pubmed: 22080957
Curr Protoc Neurosci. 2018 Apr;83(1):e48
pubmed: 30040229
Endocrinol Metab Clin North Am. 2020 Sep;49(3):347-355
pubmed: 32741475
In Vitro Cell Dev Biol. 1991 Mar;27A(3 Pt 1):188-90
pubmed: 2033018
Mol Endocrinol. 2007 Jun;21(6):1458-66
pubmed: 17426285
Stem Cell Res. 2016 Sep;17(2):318-329
pubmed: 27596959
Nat Cancer. 2022 Apr;3(4):418-436
pubmed: 35469014
Cell Tissue Res. 2014 Jul;357(1):323-35
pubmed: 24770895
J Clin Endocrinol Metab. 2008 Nov;93(11):4351-9
pubmed: 18728160
Semin Immunol. 2018 Dec;40:49-60
pubmed: 30396810
Annu Rev Pathol. 2020 Jan 24;15:211-234
pubmed: 31550983
J Mol Endocrinol. 2017 May;58(4):R241-R253
pubmed: 28381401
J Endocrinol. 2019 Feb 1;240(2):R21-R45
pubmed: 30530903
Curr Top Dev Biol. 2013;106:1-47
pubmed: 24290346
Toxicol Appl Pharmacol. 2016 Dec 15;313:204-214
pubmed: 27702603
Physiol Rev. 2007 Jul;87(3):933-63
pubmed: 17615393
Stem Cell Reports. 2015 Dec 8;5(6):1196-1209
pubmed: 26651607
Arch Med Sci. 2019 Dec 31;16(1):27-33
pubmed: 32051702
Nat Commun. 2017 Nov 28;8(1):1819
pubmed: 29180744
Pituitary. 2020 Apr;23(2):182-188
pubmed: 31728905
Cell Stem Cell. 2018 Mar 1;22(3):454-467.e6
pubmed: 29337182
Neuroendocrinology. 2022;112(1):15-33
pubmed: 33524974
Stem Cells. 2009 May;27(5):1182-95
pubmed: 19418455
J Neuroendocrinol. 1998 Mar;10(3):207-15
pubmed: 9576609
Toxicology. 2019 Nov 1;427:152306
pubmed: 31593742
EBioMedicine. 2021 Apr;66:103294
pubmed: 33773184
Acta Neuropathol. 2012 Aug;124(2):259-71
pubmed: 22349813
Cells. 2022 Oct 23;11(21):
pubmed: 36359740
Nat Rev Mol Cell Biol. 2020 Oct;21(10):571-584
pubmed: 32636524
Dev Cell. 2016 Sep 26;38(6):590-600
pubmed: 27676432
Biofabrication. 2019 Feb 05;11(2):025006
pubmed: 30537696
Transl Res. 2023 Jun;256:56-72
pubmed: 36640905
J Clin Invest. 2020 Feb 3;130(2):641-654
pubmed: 31845906
Endocrinology. 1982 Feb;110(2):513-23
pubmed: 6799274
Cell. 2018 Jan 11;172(1-2):373-386.e10
pubmed: 29224780
Endocr Relat Cancer. 2017 Apr;24(4):C5-C8
pubmed: 28264912
Biomolecules. 2022 Nov 24;12(12):
pubmed: 36551172
Endocrinology. 1955 Nov;57(5):599-607
pubmed: 13270723
J Mol Cell Biol. 2020 Aug 1;12(8):630-643
pubmed: 32678871
Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2907-12
pubmed: 18287078
Development. 1998 Mar;125(6):1005-15
pubmed: 9463347
Sci Transl Med. 2016 Jun 22;8(344):344ra84
pubmed: 27334259
Endocr Relat Cancer. 2013 May 20;20(3):R101-11
pubmed: 23689382
J Mol Endocrinol. 2015 Apr;54(2):R55-73
pubmed: 25587054
Endocrinology. 2009 Feb;150(2):1061-8
pubmed: 18927214
Cell Rep. 2020 Jan 7;30(1):18-24.e5
pubmed: 31914385
Acta Histochem Cytochem. 2014;47(5):239-45
pubmed: 25861130
Endocr Rev. 2009 Dec;30(7):790-829
pubmed: 19837867
Acta Histochem. 2015 May-Jun;117(4-5):355-66
pubmed: 25858531
Cell Stem Cell. 2013 Oct 3;13(4):419-32
pubmed: 24094323
J Clin Med. 2019 Dec 21;9(1):
pubmed: 31877737
Neuro Oncol. 2021 Nov 2;23(11):1859-1871
pubmed: 33908609
Endocrinology. 2005 May;146(5):2376-87
pubmed: 15677762
Methods Mol Biol. 2017;1597:57-65
pubmed: 28361310
Neuron. 1997 Jul;19(1):103-13
pubmed: 9247267
Mol Cell Endocrinol. 2004 Dec 30;228(1-2):1-21
pubmed: 15541569
Cell Stem Cell. 2013 Oct 3;13(4):433-45
pubmed: 24094324
Stem Cells Dev. 2012 Dec 10;21(18):3245-57
pubmed: 22970885
Mol Endocrinol. 2006 Dec;20(12):3293-307
pubmed: 16959876
Rev Endocr Metab Disord. 2005 Aug;6(3):161-72
pubmed: 16151620
Neuro Oncol. 2019 Oct 9;21(10):1273-1283
pubmed: 31222332
Onco Targets Ther. 2016 Nov 22;9:7207-7218
pubmed: 27920558
Eur Endocrinol. 2019 Apr;15(1):30-40
pubmed: 31244908
Nat Med. 2015 Mar;21(3):256-62
pubmed: 25706875
Nat Commun. 2016 Jan 14;7:10351
pubmed: 26762480
Cancers (Basel). 2022 Jul 27;14(15):
pubmed: 35954322

Auteurs

Emma Laporte (E)

Department of Development and Regeneration, Cluster of Stem Cell and Developmental Biology, Laboratory of Tissue Plasticity in Health and Disease, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.

Hugo Vankelecom (H)

Department of Development and Regeneration, Cluster of Stem Cell and Developmental Biology, Laboratory of Tissue Plasticity in Health and Disease, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.

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Classifications MeSH