Percutaneous mechanical circulatory support from the collaborative multicenter Mechanical Unusual Support in TAVI (MUST) Registry.


Journal

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
ISSN: 1522-726X
Titre abrégé: Catheter Cardiovasc Interv
Pays: United States
ID NLM: 100884139

Informations de publication

Date de publication:
15 11 2021
Historique:
received: 08 02 2021
accepted: 21 04 2021
pubmed: 8 5 2021
medline: 15 12 2021
entrez: 7 5 2021
Statut: ppublish

Résumé

To evaluate the use and outcomes of percutaneous mechanical circulatory support (pMCS) utilized during transcatheter aortic valve implantation (TAVI) from high-volume centers. Our international multicenter registry including 13 high-volume TAVI centers with 87 patients (76.5 ± 11.8 years, 63.2% men) who underwent TAVI for severe aortic stenosis and required pMCS (75.9% VA-ECMO, 19.5% Impella CP, 4.6% TandemHeart) during the procedure (prior to TAVI 39.1%, emergent rescue 50.6%, following TAVI 10.3%). The procedures were considered high-risk, with 50.6% having severe left ventricular dysfunction, 24.1% biventricular dysfunction, and 32.2% severe pulmonary hypertension. In-hospital and 1-year mortality were 27.5% and 49.4%, respectively. Patients with prophylactic hemodynamic support had lower periprocedural mortality compared to patients with rescue insertion of pMCS (log rank = 0.013) and patients who did not undergo cardiopulmonary resuscitation during the TAVI procedure had better short and long term survival (log rank <0.001 and 0.015, respectively). Given the overall survival rate and low frequency of pMCS-related complications, our study results support the use of pMCS prophylactically or during the course of TAVI (bailout) in order to improve clinical outcomes in high-risk procedures or in case of acute life-threatening hemodynamic collapse.

Identifiants

pubmed: 33961729
doi: 10.1002/ccd.29747
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

E862-E869

Informations de copyright

© 2021 Wiley Periodicals LLC.

Références

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Auteurs

Katia Orvin (K)

Department of Cardiology, Rabin Medical Center, Petach Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Leor Perl (L)

Department of Cardiology, Rabin Medical Center, Petach Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Uri Landes (U)

Department of Cardiology, Rabin Medical Center, Petach Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Centre for Heart Valve Innovation, St Paul's Hospital, University of British Columbia, Vancouver, Canada.

Danny Dvir (D)

Department of Cardiology, University of Washington Medical Center, Seattle, Washington, USA.

John George Webb (JG)

Centre for Heart Valve Innovation, St Paul's Hospital, University of British Columbia, Vancouver, Canada.

Marie-Elisabeth Stelzmüller (ME)

Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.

Wilfried Wisser (W)

Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.

Tamim Michael Nazif (TM)

Department of Cardiology, Columbia University Irving Medical Center, New York, New York, USA.

Isaac George (I)

Department of Cardiology, Columbia University Irving Medical Center, New York, New York, USA.

Mizuki Miura (M)

Department of Cardiac Surgery, University Heart Center Zurich, Zurich, Switzerland.

Maurizio Taramasso (M)

Department of Cardiac Surgery, University Heart Center Zurich, Zurich, Switzerland.

Thomas Pilgrim (T)

Department of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.

Monika Fürholz (M)

Department of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.

Jan-Malte Sinning (JM)

Heart Center Bonn, Department of Medicine II, University Hospital Bonn, Bonn, Germany.

Georg Nickenig (G)

Heart Center Bonn, Department of Medicine II, University Hospital Bonn, Bonn, Germany.

Chris Rumer (C)

Department of Cardiology, University of Washington Medical Center, Seattle, Washington, USA.

Giuseppe Tarantini (G)

Department of Cardiac, Vascular, Thoracic Sciences and Public Health, University of Padua, Padua, Italy.

Giulia Masiero (G)

Department of Cardiac, Vascular, Thoracic Sciences and Public Health, University of Padua, Padua, Italy.

Matjas Bunc (M)

Department for Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Peter Radsel (P)

Department for Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Azeem Latib (A)

Division of Cardiology, Montefiore Medical Center, New York, New York, USA.

Faraj Kargoli (F)

Division of Cardiology, Montefiore Medical Center, New York, New York, USA.

Alfonso Ielasi (A)

Clinical and Interventional Cardiology Unit, Istututo Clinico S. Ambrogio, Milan, Italy.

Massimo Medda (M)

Clinical and Interventional Cardiology Unit, Istututo Clinico S. Ambrogio, Milan, Italy.

Luis Nombela-Franco (L)

Cardiovascular Institute, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.

Hana Vaknin-Assa (H)

Department of Cardiology, Rabin Medical Center, Petach Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Ran Kornowski (R)

Department of Cardiology, Rabin Medical Center, Petach Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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