SARS-CoV-2 rapid antigen test: Fast-safe or dangerous? An analysis in the emergency department of an university hospital.


Journal

Journal of medical virology
ISSN: 1096-9071
Titre abrégé: J Med Virol
Pays: United States
ID NLM: 7705876

Informations de publication

Date de publication:
Sep 2021
Historique:
revised: 06 04 2021
received: 01 03 2021
accepted: 09 04 2021
pubmed: 11 5 2021
medline: 7 8 2021
entrez: 10 5 2021
Statut: ppublish

Résumé

The use of Antigen point of care tests (AgPOCT) might be an essential tool to fight the coronavirus disease 2019 (COVID-19) pandemic. Manufacturer information indicates a specificity of about 95% and there is a growing interest to use these tests area-wide. Therefore, it is necessary to clarify whether AgPOCT can be used safely for "rule-in" (detection of positive patients) and for "rule-out" (valid negative testing). Two thousand three hundred and seventy-five patients received polymerase chain reaction (PCR) testing and AgPOCT for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) regardless of symptoms. The positive predictive value of symptomatic and asymptomatic patients was compared with a cut-off threshold cycle (C

Identifiants

pubmed: 33969499
doi: 10.1002/jmv.27033
pmc: PMC8242658
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5323-5327

Informations de copyright

© 2021 The Authors. Journal of Medical Virology Published by Wiley Periodicals LLC.

Références

J Med Virol. 2021 Sep;93(9):5323-5327
pubmed: 33969499
PLoS One. 2021 Mar 31;16(3):e0248921
pubmed: 33788882
Biomarkers. 2021 May;26(3):213-220
pubmed: 33455451
J Infect. 2020 Sep;81(3):357-371
pubmed: 32615199
Nat Med. 2020 May;26(5):672-675
pubmed: 32296168
Eur J Clin Microbiol Infect Dis. 2020 Jun;39(6):1059-1061
pubmed: 32342252

Auteurs

Carola Holzner (C)

Center for Emergency Medicine, University Hospital Essen, Essen, Germany.

Dirk Pabst (D)

Center for Emergency Medicine, University Hospital Essen, Essen, Germany.

Olympia Evdoxia Anastasiou (OE)

Institute for Virology, University Hospital Essen, Essen, Germany.

Ulf Dittmer (U)

Institute for Virology, University Hospital Essen, Essen, Germany.

Randi Katrin Manegold (RK)

Center for Emergency Medicine, University Hospital Essen, Essen, Germany.

Joachim Risse (J)

Center for Emergency Medicine, University Hospital Essen, Essen, Germany.

David Fistera (D)

Center for Emergency Medicine, University Hospital Essen, Essen, Germany.

Clemens Kill (C)

Center for Emergency Medicine, University Hospital Essen, Essen, Germany.

Maximilian Falk (M)

Center for Emergency Medicine, University Hospital Essen, Essen, Germany.

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Classifications MeSH