[Molecular pathology - the key to precision oncology].

Molekylär patologi – nyckeln till målinriktad cancerbehandling.

Journal

Lakartidningen
ISSN: 1652-7518
Titre abrégé: Lakartidningen
Pays: Sweden
ID NLM: 0027707

Informations de publication

Date de publication:
10 05 2021
Historique:
entrez: 11 5 2021
pubmed: 12 5 2021
medline: 20 5 2021
Statut: epublish

Résumé

Rapidly expanding knowledge of the molecular landscape of cancers has resulted in the implementation of an increasing number of specific therapies targeted at tumors with specific molecular aberrations. In response to this development, new tools for predictive testing for molecular targets need to be implemented in routine health care. To achieve robust future molecular diagnostic pathology, and equal opportunity for patients to qualify for targeted therapy, the national working group for Solid Tumors in the initiative Genomic Medicine Sweden (GMS) aims to implement regional and national platforms for comprehensive genomic tumor profiling and linked analysis pipelines. Novel IT-infrastrucutures and recruitment of bioinformaticians and molecular biologists to hospital labotatories are paramount. The infrastructure will allow wider inclusion into clinical trials and supplement the national cancer registries with molecular »real world data« for research and evaluation of implemented cancer therapies and diagnostic procedures.

Identifiants

pubmed: 33973224
pii: 20209
pii:

Types de publication

Journal Article

Langues

swe

Sous-ensembles de citation

IM

Auteurs

Anders Edsjö (A)

PhD, överläkare, klinisk genetik och patologi,, Skånes universitetssjukhus; Lunds universitet.

Richard Palmqvist (R)

professor, överläkare, Region Västerbotten; Umeå universitet.

Felix Haglund (F)

docent, specialistläkare, klinisk patologi och cytologi, Karolinska universitetssjukhuset; Karolinska institutet.

Gisela Helenius (G)

docent, Universitetssjukhuset Örebro, Region Örebro län; Örebro universitet.

Oscar Lindqvist (O)

specialistläkare, klinisk patologi och cytologi, Universitetssjukhuset i Linköping.

Henrik Fagman (H)

universitetslektor, specialistläkare, Sahlgrenska universitetssjukhuset; Göteborgs universitet.

Johan Botling (J)

docent, överläkare, klinisk patologi, Akademiska sjukhuset; Uppsala universitet.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH