Important role of melanin for fertility in the fungus Podospora anserina.
Podospora anserina strain S
mating type
melanin
parasexuality
sexual reproduction
Journal
G3 (Bethesda, Md.)
ISSN: 2160-1836
Titre abrégé: G3 (Bethesda)
Pays: England
ID NLM: 101566598
Informations de publication
Date de publication:
07 08 2021
07 08 2021
Historique:
received:
08
03
2021
accepted:
05
05
2021
pubmed:
12
5
2021
medline:
6
1
2022
entrez:
11
5
2021
Statut:
ppublish
Résumé
Melanins are pigments used by fungi to withstand various stresses and to strengthen vegetative and reproductive structures. In Sordariales fungi, their biosynthesis starts with a condensation step catalyzed by an evolutionary-conserved polyketide synthase. Here we show that complete inactivation of this enzyme in the model ascomycete Podospora anserina through targeted deletion of the PaPks1 gene results in reduced female fertility, in contrast to a previously analyzed nonsense mutation in the same gene that retains full fertility. We also show the utility of PaPks1 mutants for detecting rare genetic events in P. anserina, such as parasexuality and possible fertilization and/or apomixis of nuclei devoid of mating-type gene.
Identifiants
pubmed: 33974074
pii: 6273665
doi: 10.1093/g3journal/jkab159
pmc: PMC8763234
pii:
doi:
Substances chimiques
Fungal Proteins
0
Melanins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© The Author(s) 2021. Published by Oxford University Press on behalf of Genetics Society of America.
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