Shining light on the neuro-immune axis in the gut.

Cell Adhesion Molecules Colitis Endothelium Humans Mucoproteins Neuroimmunomodulation

Journal

Immunity
ISSN: 1097-4180
Titre abrégé: Immunity
Pays: United States
ID NLM: 9432918

Informations de publication

Date de publication:
11 05 2021
Historique:
entrez: 12 5 2021
pubmed: 13 5 2021
medline: 7 9 2021
Statut: ppublish

Résumé

In this issue of Immunity, Schiller et al. report that local sympathetic nerve activation decreases endothelial expression of the adhesion molecule MAdCAM-1, reducing immune cell infiltration and colitis-induced inflammation. These findings suggest that local sympathetic stimulation provides a key gateway for regulating organ homeostasis.

Identifiants

DOI: 10.1016/j.immuni.2021.04.016 PMID: 33979582
pubmed: 33979582
pii: S1074-7613(21)00178-3
doi: 10.1016/j.immuni.2021.04.016
pii:
doi:

Substances chimiques

Cell Adhesion Molecules 0
Mucoproteins 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

850-852

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Nathalie Stakenborg (N)

Center of Intestinal Neuro-immune Interaction, Translational Research Center for GI Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing, KU Leuven - University of Leuven, Leuven, Belgium.

Guy E Boeckxstaens (GE)

Center of Intestinal Neuro-immune Interaction, Translational Research Center for GI Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing, KU Leuven - University of Leuven, Leuven, Belgium. Electronic address: guy.boeckxstaens@kuleuven.be.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Shining light on the neuro-immune axis in the gut.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies du côlon › Colite › Shining light on the neuro-immune axis in the gut.
questionsmedicales.fr › Tissus › Épithélium › Endothélium › Shining light on the neuro-immune axis in the gut.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Shining light on the neuro-immune axis in the gut.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Glycoprotéines › Mucoprotéines › Shining light on the neuro-immune axis in the gut.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunomodulation › Neuro-immunomodulation › Shining light on the neuro-immune axis in the gut.