Ultrasensitive determination of serotonin in human urine by a two dimensional capillary isotachophoresis-capillary zone electrophoresis hyphenated with tandem mass spectrometry.
Capillary electrophoresis
Capillary isotachophoresis
Column coupling arrangement
Human urine
Serotonin
Tandem mass spectrometry
Journal
Journal of chromatography. A
ISSN: 1873-3778
Titre abrégé: J Chromatogr A
Pays: Netherlands
ID NLM: 9318488
Informations de publication
Date de publication:
05 Jul 2021
05 Jul 2021
Historique:
received:
02
02
2021
revised:
19
04
2021
accepted:
20
04
2021
pubmed:
13
5
2021
medline:
2
6
2021
entrez:
12
5
2021
Statut:
ppublish
Résumé
A two-dimensional capillary isotachophoresis-capillary zone electrophoresis method hyphenated with tandem mass spectrometry was developed and validated for ultrasensitive quantification of serotonin in real human urine samples. Under optimal conditions, the separation was achieved within 12 min (including on-line sample preparation) with the limit of detection of 34 pg mL
Identifiants
pubmed: 33979756
pii: S0021-9673(21)00314-9
doi: 10.1016/j.chroma.2021.462190
pii:
doi:
Substances chimiques
Serotonin
333DO1RDJY
Creatinine
AYI8EX34EU
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
462190Informations de copyright
Copyright © 2021. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of Competing Interest Authors declare that they have no conflict of interest.