The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry.


Journal

The American journal of gastroenterology
ISSN: 1572-0241
Titre abrégé: Am J Gastroenterol
Pays: United States
ID NLM: 0421030

Informations de publication

Date de publication:
04 2021
Historique:
entrez: 13 5 2021
pubmed: 14 5 2021
medline: 22 6 2021
Statut: ppublish

Résumé

Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival. We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival. In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1-4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70-0.91). This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.

Identifiants

pubmed: 33982952
doi: 10.14309/ajg.0000000000001046
pii: 00000434-202104000-00035
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

811-815

Subventions

Organisme : NIDDK NIH HHS
ID : T32 DK007038
Pays : United States

Auteurs

Samuel Han (S)

1Division of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado; 2Adult and Child Center for Health Outcomes Research, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA; 3Division of Surgical Oncology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA; 4Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA; 5Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA; 6Department of Population and Data Sciences, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA; 7Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA; 8Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Rochester, Minnesota, USA.

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