Decrease in Skin Prion-Seeding Activity of Prion-Infected Mice Treated with a Compound Against Human and Animal Prions: a First Possible Biomarker for Prion Therapeutics.

Cellulose ethers Prion diseases Prions Real-time quaking-induced conversion (RT-QuIC) Serial protein misfolding cyclic amplification (sPMCA) TC-5RW

Journal

Molecular neurobiology
ISSN: 1559-1182
Titre abrégé: Mol Neurobiol
Pays: United States
ID NLM: 8900963

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 21 12 2020
accepted: 30 04 2021
pubmed: 14 5 2021
medline: 8 2 2022
entrez: 13 5 2021
Statut: ppublish

Résumé

Previous studies have revealed that the infectious scrapie isoform of prion protein (PrP

Identifiants

pubmed: 33983547
doi: 10.1007/s12035-021-02418-6
pii: 10.1007/s12035-021-02418-6
pmc: PMC8487418
doi:

Substances chimiques

Biomarkers 0
PrPSc Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4280-4292

Subventions

Organisme : NINDS NIH HHS
ID : R01 NS109532
Pays : United States
Organisme : Japan Agency for Medical Research and Development
ID : 16ek0109012h0003
Organisme : Foundation for Promotion of Material Science and Technology of Japan (JP)
ID : 19K22479
Organisme : Innovative Research Group Project of the National Natural Science Foundation of China
ID : 81671186

Informations de copyright

© 2021. The Author(s).

Références

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Auteurs

Mingxuan Ding (M)

Department of Neurology, The First Hospital of Jilin University, Changchun, 130021, Jilin Province, China.
Departments of Pathology and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.

Kenta Teruya (K)

Department of Neurochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.

Weiguanliu Zhang (W)

Department of Neurology, The First Hospital of Jilin University, Changchun, 130021, Jilin Province, China.
Departments of Pathology and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.

Hae Weon Lee (HW)

Departments of Pathology and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.

Jue Yuan (J)

Departments of Pathology and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.

Ayumi Oguma (A)

Department of Neurochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.

Aaron Foutz (A)

Departments of Pathology and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.

Manuel V Camacho (MV)

Departments of Pathology and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.

Marcus Mitchell (M)

Departments of Pathology and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.

Justin J Greenlee (JJ)

Virus and Prion Research Unit, Agricultural Research Service, National Animal Disease Center, USDA, 1920 Dayton Avenue, Ames, IA, 50010, USA.

Qingzhong Kong (Q)

Departments of Pathology and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.

Katsumi Doh-Ura (K)

Department of Neurochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan. doh-ura@med.tohoku.ac.jp.

Li Cui (L)

Department of Neurology, The First Hospital of Jilin University, Changchun, 130021, Jilin Province, China. chuili1967@126.com.

Wen-Quan Zou (WQ)

Departments of Pathology and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA. wxz6@case.edu.
National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA. wxz6@case.edu.

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Classifications MeSH