Lifestyle changes and risk of cancer: experience from the Swedish women's lifestyle and health cohort study.


Journal

Acta oncologica (Stockholm, Sweden)
ISSN: 1651-226X
Titre abrégé: Acta Oncol
Pays: England
ID NLM: 8709065

Informations de publication

Date de publication:
Jul 2021
Historique:
pubmed: 15 5 2021
medline: 19 8 2021
entrez: 14 5 2021
Statut: ppublish

Résumé

The impact of lifestyle changes on cancer risk is yet to be elucidated. We investigated this issue in the Swedish Women's Lifestyle and Health Cohort Study. We measured changes by comparing two questionnaires, filled in 1991/92 and 2003. We followed women for cancer from 2003 until 2012. We used Cox regression models to assess the effect of changes in smoking, alcohol consumption, body mass index (BMI), physical activity and a lifestyle score on the risk of lifestyle-related cancer. One point was added to the lifestyle score for each of these: non-smoking, alcohol consumption ≤12 grams/day, BMI <25 kg/m We included 29,930 women. From 1991/92 to 2003, median age changed from 40.0 to 51.7 years, alcohol consumption from 2.5 to 4.7 grams/day, BMI from 22.7 to 24.5 kg/m Healthy lifestyle changes, particularly smoking cessation and weight reduction, were associated with a decreased risk of cancer.

Sections du résumé

BACKGROUND BACKGROUND
The impact of lifestyle changes on cancer risk is yet to be elucidated. We investigated this issue in the Swedish Women's Lifestyle and Health Cohort Study.
MATERIAL AND METHODS METHODS
We measured changes by comparing two questionnaires, filled in 1991/92 and 2003. We followed women for cancer from 2003 until 2012. We used Cox regression models to assess the effect of changes in smoking, alcohol consumption, body mass index (BMI), physical activity and a lifestyle score on the risk of lifestyle-related cancer. One point was added to the lifestyle score for each of these: non-smoking, alcohol consumption ≤12 grams/day, BMI <25 kg/m
RESULTS RESULTS
We included 29,930 women. From 1991/92 to 2003, median age changed from 40.0 to 51.7 years, alcohol consumption from 2.5 to 4.7 grams/day, BMI from 22.7 to 24.5 kg/m
CONCLUSIONS CONCLUSIONS
Healthy lifestyle changes, particularly smoking cessation and weight reduction, were associated with a decreased risk of cancer.

Identifiants

pubmed: 33988490
doi: 10.1080/0284186X.2021.1919756
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

827-834

Auteurs

Edoardo Botteri (E)

Department of Research, Cancer Registry of Norway, Oslo, Norway.
Section for Colorectal Cancer Screening, Cancer Registry of Norway, Oslo, Norway.

Paula Berstad (P)

Section for Colorectal Cancer Screening, Cancer Registry of Norway, Oslo, Norway.

Sven Sandin (S)

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Seaver Autism Center for Research and Treatment at Mount Sinai, New York, NY, USA.

Elisabete Weiderpass (E)

International Agency for Research on Cancer, Lyon, France.

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Classifications MeSH