Evaluation of the durability of long-lasting insecticidal nets in Guatemala.
Bio-efficacy
Deltamethrin
Durability
Insecticide content
Insecticide-treated bed nets
Long-lasting insecticidal nets
Malaria
Survivorship
attrition
Journal
Malaria journal
ISSN: 1475-2875
Titre abrégé: Malar J
Pays: England
ID NLM: 101139802
Informations de publication
Date de publication:
14 May 2021
14 May 2021
Historique:
received:
18
08
2020
accepted:
03
04
2021
entrez:
15
5
2021
pubmed:
16
5
2021
medline:
18
9
2021
Statut:
epublish
Résumé
Insecticide-treated bed nets (ITNs) are widely used for the prevention and control of malaria. In Guatemala, since 2006, ITNs have been distributed free of charge in the highest risk malaria-endemic areas and constitute one of the primary vector control measures in the country. Despite relying on ITNs for almost 15 years, there is a lack of data to inform the timely replacement of ITNs whose effectiveness becomes diminished by routine use. The survivorship, physical integrity, insecticide content and bio-efficacy of ITNs were assessed through cross-sectional surveys conducted at 18, 24 and 32 months after a 2012 distribution of PermaNet® 2.0 in a malaria focus in Guatemala. A working definition of 'LLIN providing adequate protection' was developed based on the combination of the previous parameters and usage of the net. A total of 988 ITNs were analysed (290 at 18 months, 349 at 24 months and 349 at 32 months). The functional survivorship of bed nets decreased over time, from 92% at 18 months, to 81% at 24 months and 69% at 32 months. Independent of the time of the survey, less than 80% of the bed nets that were still present in the household were reported to have been used the night before. The proportion of bed nets categorized as "in good condition" per World Health Organization (WHO) guidelines of the total hole surface area, diminished from 77% to 18 months to 58% at 32 months. The portion of ITNs with deltamethrin concentration less than 10 mg/m At 32 months, only one in five of the LLINs distributed in the campaign provided adequate protection in terms of survivorship, physical integrity, bio-efficacy and usage. Efforts to encourage the community to retain, use, and properly care for the LLINs may improve their impact. Durability assessments should be included in future campaigns.
Sections du résumé
BACKGROUND
BACKGROUND
Insecticide-treated bed nets (ITNs) are widely used for the prevention and control of malaria. In Guatemala, since 2006, ITNs have been distributed free of charge in the highest risk malaria-endemic areas and constitute one of the primary vector control measures in the country. Despite relying on ITNs for almost 15 years, there is a lack of data to inform the timely replacement of ITNs whose effectiveness becomes diminished by routine use.
METHODS
METHODS
The survivorship, physical integrity, insecticide content and bio-efficacy of ITNs were assessed through cross-sectional surveys conducted at 18, 24 and 32 months after a 2012 distribution of PermaNet® 2.0 in a malaria focus in Guatemala. A working definition of 'LLIN providing adequate protection' was developed based on the combination of the previous parameters and usage of the net. A total of 988 ITNs were analysed (290 at 18 months, 349 at 24 months and 349 at 32 months).
RESULTS
RESULTS
The functional survivorship of bed nets decreased over time, from 92% at 18 months, to 81% at 24 months and 69% at 32 months. Independent of the time of the survey, less than 80% of the bed nets that were still present in the household were reported to have been used the night before. The proportion of bed nets categorized as "in good condition" per World Health Organization (WHO) guidelines of the total hole surface area, diminished from 77% to 18 months to 58% at 32 months. The portion of ITNs with deltamethrin concentration less than 10 mg/m
CONCLUSIONS
CONCLUSIONS
At 32 months, only one in five of the LLINs distributed in the campaign provided adequate protection in terms of survivorship, physical integrity, bio-efficacy and usage. Efforts to encourage the community to retain, use, and properly care for the LLINs may improve their impact. Durability assessments should be included in future campaigns.
Identifiants
pubmed: 33990197
doi: 10.1186/s12936-021-03722-1
pii: 10.1186/s12936-021-03722-1
pmc: PMC8120849
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
219Subventions
Organisme : ACL HHS
ID : U01GH001003
Pays : United States
Organisme : Center for Health Studies, Universidad del Valle de Guatemala
ID : Not applicable
Organisme : United States Agency for International Development
ID : 5U01GH001003
Références
Rev Peru Med Exp Salud Publica. 2011 Jun;28(2):228-36
pubmed: 21845302
Malar J. 2011 Oct 13;10:299
pubmed: 21992483
Malar J. 2010 Aug 30;9:248
pubmed: 20799996
PLoS Med. 2020 Sep 18;17(9):e1003248
pubmed: 32946451
Malar J. 2015 Jun 10;14:239
pubmed: 26054336
PLoS One. 2015 Jun 05;10(6):e0128499
pubmed: 26047494
Malar J. 2010 Oct 29;9:304
pubmed: 21029477
Malar J. 2020 May 24;19(1):187
pubmed: 32448313
Malar J. 2020 Mar 30;19(1):124
pubmed: 32228592
Malar J. 2020 Mar 30;19(1):125
pubmed: 32228595
Malar J. 2014 Mar 06;13:80
pubmed: 24602340
Malar J. 2013 Feb 01;12:46
pubmed: 23374429
Malar J. 2013 Dec 20;12:456
pubmed: 24359206
Malar J. 2014 May 27;13:193
pubmed: 24884502
Malar J. 2020 May 24;19(1):189
pubmed: 32448213
BMC Infect Dis. 2014 Feb 08;14:69
pubmed: 24507444
Int J Health Geogr. 2013 Jan 18;12:3
pubmed: 23331997
Malar J. 2009 May 30;8:114
pubmed: 19480712
Am J Trop Med Hyg. 2015 Feb;92(2):286-93
pubmed: 25404079
Malar J. 2016 Feb 19;15:106
pubmed: 26891696
Malar J. 2014 Nov 27;13:464
pubmed: 25430956
J Multidiscip Healthc. 2016 May 04;9:211-7
pubmed: 27217764
Am J Trop Med Hyg. 2007 Dec;77(6 Suppl):243-8
pubmed: 18165499
Am J Trop Med Hyg. 2003 Apr;68(4 Suppl):121-7
pubmed: 12749495