Genetic testing in patients undergoing percutaneous coronary intervention: rationale, evidence and practical recommendations.
Clopidogrel
/ administration & dosage
Genetic Testing
/ methods
Hemorrhage
/ chemically induced
Humans
Percutaneous Coronary Intervention
/ methods
Platelet Aggregation Inhibitors
/ administration & dosage
Precision Medicine
/ methods
Purinergic P2Y Receptor Antagonists
/ administration & dosage
Thrombosis
/ prevention & control
Genetics
antiplatelet therapy
bleeding
p2y12 inhibitors
percutaneous coronary intervention
thrombosis
Journal
Expert review of clinical pharmacology
ISSN: 1751-2441
Titre abrégé: Expert Rev Clin Pharmacol
Pays: England
ID NLM: 101278296
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
pubmed:
18
5
2021
medline:
28
8
2021
entrez:
17
5
2021
Statut:
ppublish
Résumé
Clopidogrel is the most frequently utilized P2Y The present manuscript focuses on the rationale for the use of genetic testing to guide the selection of platelet P2Y Implementation of genetic testing as a strategy to guide the selection of therapy can result in escalation (i.e. switching to prasugrel or ticagrelor) or de-escalation (i.e. switching to clopidogrel) of P2Y
Identifiants
pubmed: 33993817
doi: 10.1080/17512433.2021.1927709
pmc: PMC9008593
mid: NIHMS1794166
doi:
Substances chimiques
Platelet Aggregation Inhibitors
0
Purinergic P2Y Receptor Antagonists
0
Clopidogrel
A74586SNO7
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
963-978Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL149752
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001427
Pays : United States
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