Case Report: Complete Necrosis of a Large Adrenocortical Cancer and Liver Metastases Achieved by Selective Arterial Embolization: A Case Study and Review of Literature.


Journal

Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782

Informations de publication

Date de publication:
2021
Historique:
received: 07 03 2021
accepted: 14 04 2021
entrez: 17 5 2021
pubmed: 18 5 2021
medline: 24 12 2021
Statut: epublish

Résumé

There is very limited experience regarding the interventional radiological treatment of adrenocortical cancer (ACC). We present the case of a 57-year-old female patient with a large, potentially unresectable left-sided ACC and two hepatic metastases. Both liver tumors were effectively treated by trans-arterial embolization (TAE), followed by TAE of the bulky primary tumor as a life-saving intervention necessitated by severe intratumoral bleeding. Surgical removal of the primary tumor revealed complete necrosis. The patient is considered tumor free after 3.5 years. To the best of our knowledge, this is the first report to show that even a primary ACC may be completely ablated by selective embolization, and the fourth to prove the curative potential of liver TAE for ACC metastases. This case highlights the potential of selective embolization in ACC treatment.

Identifiants

pubmed: 33995288
doi: 10.3389/fendo.2021.677187
pmc: PMC8121102
doi:

Types de publication

Case Reports Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

677187

Informations de copyright

Copyright © 2021 Huszty, Doros, Farkas, Kóbori, Reismann, Tőke, Tóth and Igaz.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Viszeralmedizin. 2015 Dec;31(6):414-22
pubmed: 26889145
Medicine (Baltimore). 2016 Apr;95(17):e3503
pubmed: 27124055
Radiographics. 1999 Mar-Apr;19(2):399-414
pubmed: 10194787
BMC Surg. 2015 Apr 18;15:46
pubmed: 25927963
Br J Surg. 2017 Mar;104(4):358-376
pubmed: 28199015
Urol Int. 2009;82(2):222-6
pubmed: 19322014
Ann R Coll Surg Engl. 2021 Mar;103(3):e101-e105
pubmed: 33645269
World J Surg. 2012 Jan;36(1):75-82
pubmed: 22057755
Asia Pac J Clin Oncol. 2018 Jun;14(3):279-281
pubmed: 28880439
Surgery. 2019 Jan;165(1):186-195
pubmed: 30343951
AJR Am J Roentgenol. 2013 Jul;201(1):190-201
pubmed: 23789675
J Surg Oncol. 2005 May 1;90(2):101-5
pubmed: 15844181
J Vasc Interv Radiol. 2010 Oct;21(10):1527-32
pubmed: 20801688
Horm Cancer. 2019 Dec;10(4-6):161-167
pubmed: 31468469
J Clin Endocrinol Metab. 2013 Jan;98(1):181-91
pubmed: 23150691
Cancer. 2008 Dec 1;113(11):3130-6
pubmed: 18973179
Langenbecks Arch Surg. 2015 Aug;400(6):641-59
pubmed: 26088872
J Korean Med Sci. 1991 Jun;6(2):173-6
pubmed: 1661116
EJNMMI Res. 2021 Feb 18;11(1):17
pubmed: 33604708
AJR Am J Roentgenol. 1988 Oct;151(4):819-22
pubmed: 3262286
Eur J Endocrinol. 2018 Oct 01;179(4):G1-G46
pubmed: 30299884
Eur J Endocrinol. 2015 Apr;172(4):R151-66
pubmed: 25385817
Ann Surg Oncol. 1999 Dec;6(8):719-26
pubmed: 10622498
J Clin Endocrinol Metab. 2007 Jan;92(1):148-54
pubmed: 17062775
Radiol Case Rep. 2020 Jul 03;15(9):1485-1492
pubmed: 32670446
Cancers (Basel). 2020 Mar 26;12(4):
pubmed: 32224882
Hinyokika Kiyo. 2012 Apr;58(4):193-6
pubmed: 22684259
N Engl J Med. 2012 Jun 7;366(23):2189-97
pubmed: 22551107

Auteurs

Gergely Huszty (G)

Department of Transplantation and Surgery, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Attila Doros (A)

Department of Transplantation and Surgery, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Katalin Farkas (K)

Department of Transplantation and Surgery, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

László Kóbori (L)

Department of Transplantation and Surgery, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Péter Reismann (P)

Department of Endocrinology and Department of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Department of Internal Medicine and Oncology, European Reference Network for Rare Endocrine Diseases Health Care Provider (ENDO-ERN HCP), Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Judit Tőke (J)

Department of Endocrinology and Department of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Department of Internal Medicine and Oncology, European Reference Network for Rare Endocrine Diseases Health Care Provider (ENDO-ERN HCP), Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Miklós Tóth (M)

Department of Endocrinology and Department of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Department of Internal Medicine and Oncology, European Reference Network for Rare Endocrine Diseases Health Care Provider (ENDO-ERN HCP), Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Peter Igaz (P)

Department of Endocrinology and Department of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Department of Internal Medicine and Oncology, European Reference Network for Rare Endocrine Diseases Health Care Provider (ENDO-ERN HCP), Faculty of Medicine, Semmelweis University, Budapest, Hungary.
MTA-SE Molecular Medicine Research Group, Eotvos Lorand Research Network, Budapest, Hungary.

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