Association between Low Muscle Mass and Inflammatory Cytokines.
Journal
BioMed research international
ISSN: 2314-6141
Titre abrégé: Biomed Res Int
Pays: United States
ID NLM: 101600173
Informations de publication
Date de publication:
2021
2021
Historique:
received:
01
02
2021
revised:
31
03
2021
accepted:
16
04
2021
entrez:
17
5
2021
pubmed:
18
5
2021
medline:
26
5
2021
Statut:
epublish
Résumé
Sarcopenia is a multifaceted geriatric syndrome associated with the loss of muscle mass. We examined the relationship between low muscle mass and inflammatory cytokines in the context of aging. This study involved 299 participants (127 men and 172 women; mean age 63.3 ± 9.8 years) who underwent health checkups for body composition and inflammatory cytokine (TNF-alpha, IL-6, and MCP-1) levels. Muscle mass was determined using the skeletal muscle mass index. We divided the participants into the normal (N) and low muscle mass (L) groups and compared the levels of inflammatory cytokines in nonelderly (<65 years) and elderly (≥65 years) participants. Among the nonelderly subjects, C-reactive protein was significantly lower in the L group than in the N group (
Identifiants
pubmed: 33997015
doi: 10.1155/2021/5572742
pmc: PMC8099521
doi:
Substances chimiques
Cytokines
0
Inflammation Mediators
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
5572742Informations de copyright
Copyright © 2021 Sadayuki Ito et al.
Déclaration de conflit d'intérêts
The authors declare that there is no conflict of interest regarding the publication of this paper.
Références
Arch Osteoporos. 2011;6:13-20
pubmed: 22207875
Cytokine. 2020 Mar;127:154933
pubmed: 31778959
Aging Clin Exp Res. 2012 Oct;24(5):412-22
pubmed: 22717404
J Am Med Dir Assoc. 2014 Feb;15(2):95-101
pubmed: 24461239
Am J Med. 2006 Jun;119(6):526.e9-17
pubmed: 16750969
Exerc Sport Sci Rev. 2009 Oct;37(4):165-70
pubmed: 19955865
Mod Rheumatol. 2019 May;29(3):496-502
pubmed: 29694263
Nutrients. 2015 Dec 16;7(12):10513-24
pubmed: 26694460
J Biomed Biotechnol. 2010;2010:520258
pubmed: 20224659
J Biol Chem. 2006 Sep 8;281(36):26602-14
pubmed: 16809344
Clin Cases Miner Bone Metab. 2015 Jan-Apr;12(1):22-6
pubmed: 26136791
Int J Chron Obstruct Pulmon Dis. 2007;2(3):289-300
pubmed: 18229567
N Engl J Med. 1996 Dec 19;335(25):1897-905
pubmed: 8948566
Blood. 1996 Mar 15;87(6):2095-147
pubmed: 8630372
FASEB J. 2011 Oct;25(10):3344-55
pubmed: 21697550
Clin Nutr. 2004 Dec;23(6):1430-53
pubmed: 15556267
Scand J Med Sci Sports. 2010 Feb;20(1):28-38
pubmed: 19804579
Physiol Rev. 2019 Jan 1;99(1):427-511
pubmed: 30427277
J Diabetes Complications. 2016 Mar;30(2):343-9
pubmed: 26620129
FASEB J. 2005 Apr;19(6):668-70
pubmed: 15665035
Mod Rheumatol. 2018 Mar;28(2):345-350
pubmed: 28741974
J Clin Invest. 2006 Jun;116(6):1494-505
pubmed: 16691291
J Gerontol A Biol Sci Med Sci. 2002 May;57(5):M326-32
pubmed: 11983728
Curr Opin Clin Nutr Metab Care. 2010 Jan;13(1):1-7
pubmed: 19915458