The human microbiome in sickness and in health.
Disease
Enfermedad
Homeostasis
Microbioma
Microbiome
Simbiosis
Symbiosis
Journal
Revista clinica espanola
ISSN: 2254-8874
Titre abrégé: Rev Clin Esp (Barc)
Pays: Spain
ID NLM: 101632437
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
02
07
2019
accepted:
08
07
2019
entrez:
17
5
2021
pubmed:
18
5
2021
medline:
15
12
2021
Statut:
ppublish
Résumé
The study of the human microbiome has led to an exceptional increase in the current understanding of the importance of microbiota for health throughout all stages of life. Human microbial colonization occurs in the skin, genitourinary system and, mainly, in the oral cavity and intestinal tract. In these locations, the human microbiota establishes a symbiotic relationship with the host and helps maintain physiological homeostasis. Lifestyle, age, diet and use of antibiotics are the main regulators of the composition and functionality of human microbiota. Recent studies have indicated the reduction in microbial diversity as one of the contributors to the development of diseases. In addition to phylogenetic diversity studies, further metagenomic studies are needed at the functional level of the human microbiome to improve our understanding of its involvement in human health.
Identifiants
pubmed: 33998505
pii: S2254-8874(20)30003-5
doi: 10.1016/j.rceng.2019.07.018
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
233-240Informations de copyright
Copyright © 2019 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.