Placental outcomes of phthalate exposure.

Animals Endocrine Disruptors / toxicity Female Humans Maternal Exposure Phthalic Acids / toxicity Placenta / drug effects Placentation / drug effects Pregnancy
Developmental origins of health and disease Endocrine disrupting chemicals Phthalate Placenta Placenta toxicology

Journal

Reproductive toxicology (Elmsford, N.Y.)
ISSN: 1873-1708
Titre abrégé: Reprod Toxicol
Pays: United States
ID NLM: 8803591

Informations de publication

Date de publication:
08 2021
Historique:
received: 08 02 2021
revised: 14 04 2021
accepted: 05 05 2021
pubmed: 21 5 2021
medline: 15 12 2021
entrez: 20 5 2021
Statut: ppublish

Résumé

Proper placental development and function relies on hormone receptors and signaling pathways that make the placenta susceptible to disruption by endocrine disrupting chemicals, such as phthalates. Here, we review relevant research on the associations between phthalate exposures and dysfunctions of the development and function of the placenta, including morphology, physiology, and genetic and epigenetic effects. This review covers in vitro studies, in vivo studies in mammals, and studies in humans. We also discuss important gaps in the literature. Overall, the evidence indicates that toxicity to the placental and maternal-fetal interface is associated with exposure to phthalates. Further studies are needed to better elucidate the mechanisms through which phthalates act in the placenta as well as additional human studies that assess placental disruption through pregnancy with larger sample sizes.

Identifiants

DOI: 10.1016/j.reprotox.2021.05.001 PMID: 34015474 PMC: PMC8260441
pubmed: 34015474
pii: S0890-6238(21)00066-6
doi: 10.1016/j.reprotox.2021.05.001
pmc: PMC8260441
mid: NIHMS1709740
pii:
doi:

Substances chimiques

Endocrine Disruptors 0
Phthalic Acids 0
phthalic acid 6O7F7IX66E

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-17

Subventions

Organisme : NIEHS NIH HHS
ID : K99 ES031150
Pays : United States
Organisme : NIEHS NIH HHS
ID : R01 ES028661
Pays : United States
Organisme : NIEHS NIH HHS
ID : R01 ES032163
Pays : United States
Organisme : NIEHS NIH HHS
ID : T32 ES007326
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Références

Basic Clin Pharmacol Toxicol. 2008 Feb;102(2):94-9
pubmed: 18226061
Biochimie. 2018 Jun;149:1-8
pubmed: 29567412
Environ Int. 2019 Jan;122:222-230
pubmed: 30477814
Environ Mol Mutagen. 2015 Apr;56(3):286-92
pubmed: 25327576
Regul Toxicol Pharmacol. 1999 Jun;29(3):327-57
pubmed: 10388618
Environ Health Perspect. 2003 Feb;111(2):139-45
pubmed: 12573895
Biol Neonate. 2003;83(1):22-4
pubmed: 12566679
Mol Nutr Food Res. 2007 Jul;51(7):899-911
pubmed: 17604388
Toxicol Sci. 2005 Jan;83(1):4-17
pubmed: 15496498
Exp Clin Endocrinol. 1994;102(3):122-34
pubmed: 7995333
J Hazard Mater. 2015 Oct 30;297:25-33
pubmed: 25935407
Biol Reprod. 2015 May;92(5):120
pubmed: 25810477
Curr Opin Pediatr. 2015 Apr;27(2):248-53
pubmed: 25635586
Hum Reprod. 2017 Nov 1;32(11):2159-2169
pubmed: 29024969
Reprod Toxicol. 2016 Oct;65:382-393
pubmed: 27614199
Int J Dev Biol. 2010;54(2-3):525-30
pubmed: 19876839
Am J Obstet Gynecol. 2015 Oct;213(4 Suppl):S163-72
pubmed: 26428496
Environ Int. 2018 Jul;116:319-325
pubmed: 29754027
PLoS One. 2013 May 07;8(5):e62526
pubmed: 23667484
Sci Total Environ. 2016 Mar 15;547:441-446
pubmed: 26824397
J Clin Endocrinol Metab. 2002 Jun;87(6):2954-9
pubmed: 12050279
Int J Androl. 2006 Feb;29(1):134-9; discussion 181-5
pubmed: 16466533
Environ Health Perspect. 2019 Feb;127(2):27003
pubmed: 30810372
Toxicol In Vitro. 2017 Feb;38:41-48
pubmed: 27825933
Biochem Biophys Res Commun. 2005 Jul 8;332(3):853-8
pubmed: 15913554
J Reprod Immunol. 2013 Mar;97(1):51-61
pubmed: 23432872
Toxicol Pathol. 2014;42(2):339-44
pubmed: 23531795
Philos Trans R Soc Lond B Biol Sci. 2009 Jul 27;364(1526):2063-78
pubmed: 19528056
BMC Genomics. 2011 Oct 28;12:529
pubmed: 22032438
Environ Health Perspect. 2017 Oct 31;125(10):107010
pubmed: 29089286
Toxicol Appl Pharmacol. 2013 Apr 1;268(1):47-54
pubmed: 23360888
Am J Obstet Gynecol. 2010 Apr;202(4):391.e1-8
pubmed: 20350649
Placenta. 2015 Apr;36 Suppl 1:S50-9
pubmed: 25524059
Bull Environ Contam Toxicol. 2004 Jun;72(6):1226-31
pubmed: 15362453
Hum Exp Toxicol. 2021 Mar;40(3):504-514
pubmed: 32909833
J Am Coll Nutr. 2004 Dec;23(6 Suppl):588S-595S
pubmed: 15640511
PLoS One. 2019 May 14;14(5):e0214873
pubmed: 31086358
Environ Health Perspect. 2010 Feb;118(2):291-6
pubmed: 20123604
Toxicol Appl Pharmacol. 2001 May 1;172(3):217-24
pubmed: 11312650
Reprod Toxicol. 2002 Sep-Oct;16(5):529-653
pubmed: 12406494
Environ Int. 2019 Oct;131:105057
pubmed: 31398592
Annu Rev Physiol. 2011;73:135-62
pubmed: 21054169
Semin Reprod Med. 2016 Jan;34(1):11-6
pubmed: 26752715
Placenta. 2015 Apr;36(4):372-80
pubmed: 25618838
Environ Sci Technol. 2003 Oct 15;37(20):4543-53
pubmed: 14594359
Environ Health. 2016 May 04;15(1):59
pubmed: 27142700
Placenta. 2017 Dec;60:134-139
pubmed: 28651899
Environ Health. 2017 Apr 5;16(1):35
pubmed: 28381288
Semin Reprod Med. 2016 Jan;34(1):36-41
pubmed: 26696277
Trends Endocrinol Metab. 2020 Jul;31(7):508-524
pubmed: 32249015
Environ Res. 2019 Feb;169:272-279
pubmed: 30497002
Reprod Toxicol. 2007 Aug-Sep;24(2):139-77
pubmed: 17825522
J Steroid Biochem Mol Biol. 2011 Nov;127(3-5):204-15
pubmed: 21899826
Nat Rev Mol Cell Biol. 2006 Jul;7(7):505-16
pubmed: 16829981
Hum Reprod. 2015 Apr;30(4):789-99
pubmed: 25740878
Toxicol Appl Pharmacol. 1994 Oct;128(2):224-8
pubmed: 7940537
Arch Toxicol. 2017 Feb;91(2):689-698
pubmed: 27071666
Environ Pollut. 2020 Feb;257:113593
pubmed: 31771930
Environ Res. 2019 May;172:194-201
pubmed: 30802670
Mol Cell Endocrinol. 2012 Sep 25;361(1-2):106-15
pubmed: 22526026
J Enzyme Inhib Med Chem. 2008 Oct;23(5):611-6
pubmed: 18821250
Rev Reprod. 1997 May;2(2):105-12
pubmed: 9414472
Placenta. 2008 Nov;29(11):962-9
pubmed: 18829104
J Appl Toxicol. 2019 Jul;39(7):1043-1056
pubmed: 30847963
Toxicology. 2005 Feb 1;207(1):149-63
pubmed: 15590130
Birth Defects Res A Clin Mol Teratol. 2011 Aug;91(8):682-92
pubmed: 21648055
Endocrinology. 2019 Jun 1;160(6):1421-1435
pubmed: 30998239
Endocr Rev. 2015 Dec;36(6):E1-E150
pubmed: 26544531
Anal Chem. 2000 Sep 1;72(17):4127-34
pubmed: 10994974
Arch Toxicol. 2004 Mar;78(3):123-30
pubmed: 14576974
Placenta. 2012 May;33(5):327-34
pubmed: 22374510
Sci Rep. 2016 Sep 22;6:33449
pubmed: 27653773
Toxicology. 2005 Jun 1;210(2-3):223-33
pubmed: 15840436
Front Genet. 2013 Sep 26;4:190
pubmed: 24133501
Environ Health Perspect. 2016 Mar;124(3):380-7
pubmed: 26090578
Biol Reprod. 2012 Dec 27;87(6):152
pubmed: 23077170
Toxicol Sci. 2018 May 1;163(1):116-122
pubmed: 29385630
Reprod Toxicol. 2018 Jan;75:121-126
pubmed: 29061543
Endocr Rev. 2012 Jun;33(3):378-455
pubmed: 22419778
Mol Cell Endocrinol. 1998 May 25;140(1-2):115-20
pubmed: 9722178
Placenta. 2013 Mar;34 Suppl:S34-9
pubmed: 23153501
Int Arch Occup Environ Health. 2012 Apr;85(3):317-25
pubmed: 21701833
Regul Toxicol Pharmacol. 2004 Oct;40(2):151-67
pubmed: 15450718
Biol Reprod. 2004 Jun;70(6):1806-13
pubmed: 14973263
Reprod Sci. 2019 Feb;26(2):289-294
pubmed: 29690855
Reprod Health. 2018 Feb 23;15(1):33
pubmed: 29471860
Hum Reprod. 2017 Jan;32(1):65-75
pubmed: 27927842
Toxicol Ind Health. 1987 Jun;3(2):165-83
pubmed: 3617066
Mol Cell Ther. 2015 Jun 12;3:5
pubmed: 26082843
Am J Obstet Gynecol. 2015 Oct;213(4 Suppl):S173-81
pubmed: 26428497
Reproduction. 2009 Jun;137(6):1007-15
pubmed: 19279199
Reprod Toxicol. 2016 Jun;61:151-61
pubmed: 27067917
Eur Heart J. 2011 Sep;32(18):2297-303
pubmed: 21632601
Toxicol Lett. 2018 Sep 15;294:1-10
pubmed: 29753845
Placenta. 2012 Oct;33(10):874-7
pubmed: 22800585
Environ Health. 2014 Jun 25;13(1):46
pubmed: 24961440
Reprod Toxicol. 2018 Apr;77:154-165
pubmed: 29505797
Environ Res. 2014 Aug;133:396-406
pubmed: 24972507
Placenta. 2012 Sep;33(9):725-34
pubmed: 22721760
Reprod Biomed Online. 2012 Jul;25(1):68-89
pubmed: 22560117
J Assist Reprod Genet. 2012 Aug;29(8):773-7
pubmed: 22538552
Nutrients. 2020 Jun 11;12(6):
pubmed: 32545151
Toxicol Sci. 2018 Dec 01;166(2):250-268
pubmed: 30203063
Environ Sci Technol. 2017 Apr 4;51(7):4061-4068
pubmed: 28282128
Environ Health Perspect. 2017 Aug 31;125(8):087026
pubmed: 28934718
Environ Sci Pollut Res Int. 2018 Jul;25(21):21205-21215
pubmed: 29777495
Environ Sci Pollut Res Int. 2017 Feb;24(5):4537-4551
pubmed: 27943041
Curr Opin Pediatr. 2013 Apr;25(2):247-54
pubmed: 23429708
Int J Environ Res Public Health. 2020 Sep 18;17(18):
pubmed: 32961939
Nature. 2004 Sep 16;431(7006):350-5
pubmed: 15372042
Toxicol Appl Pharmacol. 2019 Sep 1;378:114635
pubmed: 31233757
PLoS One. 2016 Jan 11;11(1):e0147013
pubmed: 26751383
Arch Toxicol. 2005 Nov;79(11):647-52
pubmed: 15995852
Reprod Biol Endocrinol. 2015 Jun 03;13:56
pubmed: 26036283
Toxicol Ind Health. 2017 Sep;33(9):696-716
pubmed: 28854868
Eur J Hum Genet. 2010 Sep;18(9):1006-12
pubmed: 20442742
Adv Healthc Mater. 2018 Jan;7(2):
pubmed: 29121458
Toxicol Appl Pharmacol. 2020 May 1;394:114960
pubmed: 32201330
Nat Rev Genet. 2001 Jan;2(1):21-32
pubmed: 11253064
Endocr Rev. 2009 Jun;30(4):293-342
pubmed: 19502515
Front Endocrinol (Lausanne). 2018 Sep 27;9:570
pubmed: 30319550
Chem Res Toxicol. 2016 Mar 21;29(3):430-5
pubmed: 26871967
Toxicol Appl Pharmacol. 2017 Jul 15;327:23-29
pubmed: 28416457
Nature. 2001 Feb 15;409(6822):860-921
pubmed: 11237011
Hum Reprod Update. 2019 Nov 5;25(6):777-801
pubmed: 31633761
Nat Rev Endocrinol. 2020 Sep;16(9):479-494
pubmed: 32601352
Am J Hum Biol. 2013 Jul-Aug;25(4):534-7
pubmed: 23657899
Reprod Toxicol. 2020 Mar;92:14-56
pubmed: 31055053
Reprod Toxicol. 2016 Jun;61:142-50
pubmed: 27067915
Environ Health Perspect. 2019 Jan;127(1):17002
pubmed: 30624098
Environ Health Perspect. 2009 Oct;117(10):1587-92
pubmed: 20019910
Reprod Toxicol. 2017 Jan;67:117-124
pubmed: 27956250
ScientificWorldJournal. 2012;2012:615068
pubmed: 23213291
Environ Health. 2009 Apr 23;8:20
pubmed: 19389254
J Toxicol Pathol. 2013 Mar;26(1):83-8
pubmed: 23723574
J Toxicol Pathol. 2014 Apr;27(1):11-8
pubmed: 24791062
Sci Rep. 2016 Feb 12;6:21004
pubmed: 26867681
Front Immunol. 2018 Nov 13;9:2597
pubmed: 30483261
Sci Rep. 2018 Apr 17;8(1):6086
pubmed: 29666409
Adv Anat Embryol Cell Biol. 1989;115:1-112
pubmed: 2658485
Adv Drug Deliv Rev. 1999 Jun 14;38(1):41-58
pubmed: 10837745
Environ Health Perspect. 2011 Jun;119(6):878-85
pubmed: 21233055
Environ Res. 2018 Jan;160:239-246
pubmed: 29028488
Occup Environ Med. 2005 Nov;62(11):806-18
pubmed: 16234408
Toxicol In Vitro. 2016 Mar;31:35-42
pubmed: 26597031
Front Endocrinol (Lausanne). 2015 Feb 02;6:8
pubmed: 25699018
Placenta. 2012 Apr;33(4):233-43
pubmed: 22284666
Reprod Toxicol. 2004 Nov;19(1):27-33
pubmed: 15336709
Arch Toxicol. 2006 May;80(5):293-8
pubmed: 16328440
J Toxicol Pathol. 2019 Jan;32(1):1-17
pubmed: 30739991
Placenta. 2017 Feb;50:1-7
pubmed: 28161053
Cell Adh Migr. 2016 Mar 3;10(1-2):88-110
pubmed: 26743330
Genes Dev. 2002 Jan 1;16(1):6-21
pubmed: 11782440
Hum Reprod. 2003 Jul;18(7):1512-5
pubmed: 12832380
Front Physiol. 2016 Feb 05;7:28
pubmed: 26903878
J Expo Sci Environ Epidemiol. 2018 Sep;28(5):448-460
pubmed: 30018406
Epigenomics. 2011 Jun;3(3):267-77
pubmed: 22122337
Endocrinology. 2012 Sep;153(9):4097-110
pubmed: 22733974

Auteurs

Genoa R Warner (GR)

Dept of Comparative Biosciences, University of Illinois, Urbana, IL, USA.

Raquel S Dettogni (RS)

Dept of Morphology, Federal University of Espirito Santo, Brazil.

Indrani C Bagchi (IC)

Dept of Comparative Biosciences, University of Illinois, Urbana, IL, USA.

Jodi A Flaws (JA)

Dept of Comparative Biosciences, University of Illinois, Urbana, IL, USA. Electronic address: jflaws@illinois.edu.

Jones B Graceli (JB)

Dept of Morphology, Federal University of Espirito Santo, Brazil.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Placental outcomes of phthalate exposure.
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Perturbateurs endocriniens › Placental outcomes of phthalate exposure.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Placental outcomes of phthalate exposure.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Exposition environnementale › Exposition maternelle › Placental outcomes of phthalate exposure.
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides carbocycliques › Acides phtaliques › Placental outcomes of phthalate exposure.
questionsmedicales.fr › Structures de l'embryon › Placenta › Placental outcomes of phthalate exposure.
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Placentation › Placental outcomes of phthalate exposure.
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Placental outcomes of phthalate exposure.