Predictors of Failure of Mitral Valve Repair Using Artificial Chordae.


Journal

The Annals of thoracic surgery
ISSN: 1552-6259
Titre abrégé: Ann Thorac Surg
Pays: Netherlands
ID NLM: 15030100R

Informations de publication

Date de publication:
04 2022
Historique:
received: 16 01 2021
revised: 01 04 2021
accepted: 27 04 2021
pubmed: 23 5 2021
medline: 12 4 2022
entrez: 22 5 2021
Statut: ppublish

Résumé

We investigated predictors of failure of mitral valve repair (MVr) using expanded polytetrafluoroethylene (ePTFE) and its durability in the long term in a single institution. Four hundred twenty-one consecutive patients with primary mitral valve disease underwent MVr using artificial chordae (group A, n = 304) and suture repair (group S, n = 117) at our institution from January 2002 to April 2020. A comparison study was performed to examine the long-term outcomes, reoperation rate, and risk factors for reoperation. One hospital death and 5 late deaths occurred in group S, and 20 late deaths occurred in group A. The reoperation rates were similar: group A, n = 8 (2.6%); and group S, n = 6 (5%). The major cause of reoperation was ruptured ePTFE (CV-4, n = 1; CV-5, n = 6) in group A, and suture rupture in group S. Reoperation was performed after a median of 88 months for ruptured ePTFE, and 26 months for group S. The rate of ePTFE rupture was 1.8% with CV-5 and 0.2% with CV-4. Risk factors for reoperation included postoperative arrhythmia, urgent operation, no annular ring, ruptured ePTFE, and suture rupture. The rates of freedom from reoperation and actuarial mitral valve survival rates at 5, 10, and 15 years were 99%, 95%, and 93% and 96%, 91%, and 89%, respectively, in group A; and 96%, 91%, and 91% and 95%, 94%, and 94%, respectively, in group S. The long-term surgical outcomes of MVr using both techniques were feasible. Over the long term, the ePTFE rupture rate of CV-5 was higher than that of CV-4.

Sections du résumé

BACKGROUND
We investigated predictors of failure of mitral valve repair (MVr) using expanded polytetrafluoroethylene (ePTFE) and its durability in the long term in a single institution.
METHODS
Four hundred twenty-one consecutive patients with primary mitral valve disease underwent MVr using artificial chordae (group A, n = 304) and suture repair (group S, n = 117) at our institution from January 2002 to April 2020. A comparison study was performed to examine the long-term outcomes, reoperation rate, and risk factors for reoperation.
RESULTS
One hospital death and 5 late deaths occurred in group S, and 20 late deaths occurred in group A. The reoperation rates were similar: group A, n = 8 (2.6%); and group S, n = 6 (5%). The major cause of reoperation was ruptured ePTFE (CV-4, n = 1; CV-5, n = 6) in group A, and suture rupture in group S. Reoperation was performed after a median of 88 months for ruptured ePTFE, and 26 months for group S. The rate of ePTFE rupture was 1.8% with CV-5 and 0.2% with CV-4. Risk factors for reoperation included postoperative arrhythmia, urgent operation, no annular ring, ruptured ePTFE, and suture rupture. The rates of freedom from reoperation and actuarial mitral valve survival rates at 5, 10, and 15 years were 99%, 95%, and 93% and 96%, 91%, and 89%, respectively, in group A; and 96%, 91%, and 91% and 95%, 94%, and 94%, respectively, in group S.
CONCLUSIONS
The long-term surgical outcomes of MVr using both techniques were feasible. Over the long term, the ePTFE rupture rate of CV-5 was higher than that of CV-4.

Identifiants

pubmed: 34022210
pii: S0003-4975(21)00864-X
doi: 10.1016/j.athoracsur.2021.04.084
pii:
doi:

Substances chimiques

Polytetrafluoroethylene 9002-84-0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1136-1143

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2022 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Auteurs

Masato Mutsuga (M)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address: mutsuga@med.nagoya-u.ac.jp.

Yuji Narita (Y)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Yoshiyuki Tokuda (Y)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Wataru Uchida (W)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Hideki Ito (H)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Sachie Terazawa (S)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Masato Nakaguro (M)

Department of Pathology and Laboratory medicine, Nagoya University Hospital, Nagoya, Japan.

Akihiko Usui (A)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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