Curcuminoid-Tailored Interfacial Free Energy of Hydrophobic Fibers for Enhanced Biological Properties.
Carbon-13 Magnetic Resonance Spectroscopy
Cell Line
Cell Survival
/ drug effects
Diarylheptanoids
/ chemistry
Extracellular Matrix
/ chemistry
Humans
Hydrophobic and Hydrophilic Interactions
Microscopy, Electron, Scanning
Polyesters
/ chemistry
Proton Magnetic Resonance Spectroscopy
Tissue Engineering
/ methods
SH-SY5Y cells
cell adhesion
cell proliferation
curcuminoids
electrospinning
poly(lactic acid)
surface free energy
Journal
ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991
Informations de publication
Date de publication:
02 Jun 2021
02 Jun 2021
Historique:
pubmed:
25
5
2021
medline:
19
8
2021
entrez:
24
5
2021
Statut:
ppublish
Résumé
The ability of mimicking the extracellular matrix architecture has gained electrospun scaffolds a prominent space into the tissue engineering field. The high surface-to-volume aspect ratio of nanofibers increases their bioactivity while enhancing the bonding strength with the host tissue. Over the years, numerous polyesters, such as poly(lactic acid) (PLA), have been consolidated as excellent matrices for biomedical applications. However, this class of polymers usually has a high hydrophobic character, which limits cell attachment and proliferation, and therefore decreases biological interactions. In this way, functionalization of polyester-based materials is often performed in order to modify their interfacial free energy and achieve more hydrophilic surfaces. Herein, we report the preparation, characterization, and
Identifiants
pubmed: 34024099
doi: 10.1021/acsami.1c05034
pmc: PMC8289194
doi:
Substances chimiques
Diarylheptanoids
0
Polyesters
0
poly(lactide)
459TN2L5F5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
24493-24504Références
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