Neurorehabilitation From a Distance: Can Intelligent Technology Support Decentralized Access to Quality Therapy?

clinical intelligence decentralized care neurorehabilitation robot-assisted therapy (RAT) stroke

Journal

Frontiers in robotics and AI
ISSN: 2296-9144
Titre abrégé: Front Robot AI
Pays: Switzerland
ID NLM: 101749350

Informations de publication

Date de publication:
2021
Historique:
received: 30 09 2020
accepted: 20 04 2021
entrez: 24 5 2021
pubmed: 25 5 2021
medline: 25 5 2021
Statut: epublish

Résumé

Current neurorehabilitation models primarily rely on extended hospital stays and regular therapy sessions requiring close physical interactions between rehabilitation professionals and patients. The current COVID-19 pandemic has challenged this model, as strict physical distancing rules and a shift in the allocation of hospital resources resulted in many neurological patients not receiving essential therapy. Accordingly, a recent survey revealed that the majority of European healthcare professionals involved in stroke care are concerned that this lack of care will have a noticeable negative impact on functional outcomes. COVID-19 highlights an urgent need to rethink conventional neurorehabilitation and develop alternative approaches to provide high-quality therapy while minimizing hospital stays and visits. Technology-based solutions, such as, robotics bear high potential to enable such a paradigm shift. While robot-assisted therapy is already established in clinics, the future challenge is to enable physically assisted therapy and assessments in a minimally supervized and decentralized manner, ideally at the patient's home. Key enablers are new rehabilitation devices that are portable, scalable and equipped with clinical intelligence, remote monitoring and coaching capabilities. In this perspective article, we discuss clinical and technological requirements for the development and deployment of minimally supervized, robot-assisted neurorehabilitation technologies in patient's homes. We elaborate on key principles to ensure feasibility and acceptance, and on how artificial intelligence can be leveraged for embedding clinical knowledge for safe use and personalized therapy adaptation. Such new models are likely to impact neurorehabilitation beyond COVID-19, by providing broad access to sustained, high-quality and high-dose therapy maximizing long-term functional outcomes.

Identifiants

pubmed: 34026855
doi: 10.3389/frobt.2021.612415
pii: 612415
pmc: PMC8132098
doi:

Types de publication

Journal Article

Langues

eng

Pagination

612415

Informations de copyright

Copyright © 2021 Lambercy, Lehner, Chua, Wee, Rajeswaran, Kuah, Ang, Liang, Campolo, Hussain, Aguirre-Ollinger, Guan, Kanzler, Wenderoth and Gassert.

Déclaration de conflit d'intérêts

AH and DC hold equity positions in ARTICARES Pte. Ltd., a company that manufactures robotic devices for rehabilitation. AH is also the acting CEO of ARTICARES Pte. Ltd. GA-O is the acting Head of Research and Development at ARTICARES Pte. Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

IEEE Int Conf Rehabil Robot. 2019 Jun;2019:957-962
pubmed: 31374753
Neurol Sci. 2020 May;41(5):999-1001
pubmed: 32270358
Soft Robot. 2021 Apr;8(2):128-143
pubmed: 32552422
PLoS Comput Biol. 2012 Feb;8(2):e1002343
pubmed: 22761551
Lancet. 2018 Nov 10;392(10159):1859-1922
pubmed: 30415748
Phys Med Rehabil Clin N Am. 2019 May;30(2):473-483
pubmed: 30954160
Neurorehabil Neural Repair. 2019 Jul;33(7):523-537
pubmed: 31131743
IEEE J Biomed Health Inform. 2020 Sep;24(9):2630-2638
pubmed: 31902785
Clin Rehabil. 2014 Jul;28(7):637-47
pubmed: 24452706
Stroke. 2021 Jan;52(2):716-721
pubmed: 33356382
Top Stroke Rehabil. 2010 Sep-Oct;17(5):362-70
pubmed: 21131261
Neurorehabil Neural Repair. 2012 Sep;26(7):822-33
pubmed: 22374174
Neurorehabil Neural Repair. 2015 Nov-Dec;29(10):958-68
pubmed: 25782693
J Rehabil Assist Technol Eng. 2017 Jun 01;4:2055668317708732
pubmed: 31186929
J Neuroeng Rehabil. 2007 Mar 01;4:6
pubmed: 17331243
Stroke. 2016 Jun;47(6):1685-91
pubmed: 27143275
Arch Phys Med Rehabil. 2018 Dec;99(12):2472-2477.e2
pubmed: 29902469
J Med Internet Res. 2020 Aug 7;22(8):e17158
pubmed: 32763886
J Rehabil Assist Technol Eng. 2021 Apr 19;8:20556683211001805
pubmed: 33953938
Int J Stroke. 2010 Jun;5(3):178-86
pubmed: 20536615
J Neurol Neurosurg Psychiatry. 2019 May;90(5):498-506
pubmed: 30770457
J Neuroeng Rehabil. 2020 Aug 24;17(1):115
pubmed: 32831097
BMJ. 2020 Mar 26;368:m1198
pubmed: 32217618
Phys Ther. 2020 Aug 12;100(8):1260-1264
pubmed: 32386218
J Neuroeng Rehabil. 2014 Nov 15;11:154
pubmed: 25399249
Int J Stroke. 2013 Jul;8(5):357-64
pubmed: 22974010
Clin Rehabil. 2017 Feb;31(2):207-216
pubmed: 26869596
J Neuroeng Rehabil. 2020 Jun 30;17(1):83
pubmed: 32605587
J Neuroeng Rehabil. 2018 Jun 5;15(1):46
pubmed: 29866106
Eur J Neurol. 2020 Sep;27(9):1794-1800
pubmed: 32492764
Am J Phys Med Rehabil. 2020 Jul;99(7):582
pubmed: 32404640
J Neuroeng Rehabil. 2016 Sep 15;13(1):83
pubmed: 27634471
N Engl J Med. 2010 May 13;362(19):1772-83
pubmed: 20400552
J Neuroeng Rehabil. 2021 Feb 24;18(1):43
pubmed: 33627126
Biomed Eng Online. 2020 May 14;19(1):33
pubmed: 32410617
J Stroke Cerebrovasc Dis. 2020 Jul;29(7):104881
pubmed: 32334918
Neurorehabil Neural Repair. 2017 Feb;31(2):107-121
pubmed: 27597165
N Engl J Med. 2020 Jun 4;382(23):e82
pubmed: 32240581
J Med Internet Res. 2021 Feb 22;23(2):e23612
pubmed: 33461957
IEEE Int Conf Rehabil Robot. 2019 Jun;2019:1159-1166
pubmed: 31374786
Front Hum Neurosci. 2016 Dec 20;10:640
pubmed: 28066211
Front Bioeng Biotechnol. 2021 Apr 15;9:652380
pubmed: 33937218
Value Health. 2014 Nov;17(7):A474
pubmed: 27201365
Neurorehabil Neural Repair. 2017 Oct-Nov;31(10-11):923-933
pubmed: 29072556
J Neuroeng Rehabil. 2016 Aug 11;13(1):75
pubmed: 27515583
Eur Stroke J. 2020 Sep;5(3):230-236
pubmed: 33072876
J Neuroeng Rehabil. 2014 Dec 12;11:163
pubmed: 25495889
JMIR Mhealth Uhealth. 2018 Mar 01;6(3):e47
pubmed: 29496655
Am J Phys Med Rehabil. 2017 Oct;96(10 Suppl 1):S150-S156
pubmed: 28708632
NPJ Digit Med. 2020 May 29;3:80
pubmed: 32529042
IEEE Int Conf Rehabil Robot. 2011;2011:5975440
pubmed: 22275640
J Med Internet Res. 2014 Jan 16;16(1):e19
pubmed: 24434570
Stroke. 2000 May;31(5):1016-23
pubmed: 10797160
Yearb Med Inform. 2019 Aug;28(1):128-134
pubmed: 31022752
J Neuroeng Rehabil. 2011 Nov 16;8:63
pubmed: 22087842
J Neuroeng Rehabil. 2020 Oct 7;17(1):132
pubmed: 33028354
Eura Medicophys. 2006 Sep;42(3):241-56
pubmed: 17039223
Cochrane Database Syst Rev. 2020 Jan 31;1:CD010255
pubmed: 32002991
JMIR Mhealth Uhealth. 2019 May 28;7(5):e10465
pubmed: 31140445

Auteurs

Olivier Lambercy (O)

Rehabilitation Engineering Laboratory, Department of Health Sciences and Technology, ETH Zurich, Switzerland.
Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.

Rea Lehner (R)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
Neural Control of Movement Laboratory, Department of Health Sciences and Technology, ETH Zurich, Switzerland.

Karen Chua (K)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
Centre for Advanced Rehabilitation Therapeutics, Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.
Rehabilitation Research Institute Singapore, Nanyang Technological University, Singapore, Singapore.

Seng Kwee Wee (SK)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
Centre for Advanced Rehabilitation Therapeutics, Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.
Singapore Institute of Technology (SIT), Singapore, Singapore.

Deshan Kumar Rajeswaran (DK)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
Centre for Advanced Rehabilitation Therapeutics, Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.

Christopher Wee Keong Kuah (CWK)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
Centre for Advanced Rehabilitation Therapeutics, Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.

Wei Tech Ang (WT)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
Rehabilitation Research Institute Singapore, Nanyang Technological University, Singapore, Singapore.
School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, Singapore.

Phyllis Liang (P)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
Rehabilitation Research Institute Singapore, Nanyang Technological University, Singapore, Singapore.

Domenico Campolo (D)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, Singapore.

Asif Hussain (A)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, Singapore.
Articares Pte Ltd, Singapore, Singapore.

Gabriel Aguirre-Ollinger (G)

Articares Pte Ltd, Singapore, Singapore.

Cuntai Guan (C)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
School of Computer Science and Engineering, Nanyang Technological University, Singapore, Singapore.

Christoph M Kanzler (CM)

Rehabilitation Engineering Laboratory, Department of Health Sciences and Technology, ETH Zurich, Switzerland.
Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.

Nicole Wenderoth (N)

Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.
Neural Control of Movement Laboratory, Department of Health Sciences and Technology, ETH Zurich, Switzerland.

Roger Gassert (R)

Rehabilitation Engineering Laboratory, Department of Health Sciences and Technology, ETH Zurich, Switzerland.
Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore, Singapore.

Classifications MeSH