Myocardial blood flows and reserves on solid state camera: Correlations with coronary history and cardiovascular risk factors.


Journal

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
ISSN: 1532-6551
Titre abrégé: J Nucl Cardiol
Pays: United States
ID NLM: 9423534

Informations de publication

Date de publication:
08 2022
Historique:
received: 18 09 2020
accepted: 06 04 2021
pubmed: 27 5 2021
medline: 5 8 2022
entrez: 26 5 2021
Statut: ppublish

Résumé

Study designed to test association between stress-induced myocardial blood flow (sMBF), resting MBF (rMBF), and MBF reserve (MFR) and coronary artery disease (CAD) in a population of CAD and non-coronary patients. Secondary objectives were to confront visual analysis and dynamic analysis and to explore potential association between MBF and several cardiovascular risk factors METHODS: A total of 155 patients who underwent dynamic myocardial perfusion imaging on a CZT camera were included. sMBF, rMBF, and MFR were evaluated, and cardiovascular risk was assessed. Significantly lower total sMBF and MFR were observed in CAD patient vs non-CAD patient. In comparison with visual analysis, lower sMBF were found in pathologic territory, lower rMBF in necrotic territory and lower MFR in necrotic ones. A significant correlation between total sMBF, rMBF and diabetes was found. sMBF and MFR as assessed on CZT gamma-cameras can be used to determine the coronary state. Low total sMBF might be an independent risk factor of coronaropathy. An inverse correlation was suggested between total sMBF and rMBF with diabetes.

Identifiants

pubmed: 34036528
doi: 10.1007/s12350-021-02659-x
pii: 10.1007/s12350-021-02659-x
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1671-1678

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2021. American Society of Nuclear Cardiology.

Références

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Auteurs

Paul Ferenczi (P)

Nuclear Imaging Department, CHU de Bordeaux, 33000, Bordeaux, France. paul.ferenczi@hotmail.fr.
Nuclear imaging Department, CH de Pau, 64000, Pau, France. paul.ferenczi@hotmail.fr.

Thierry Couffinhal (T)

Cardiology Department, CHU de Bordeaux, 33000, Bordeaux, France.

Adel Mamou (A)

R&D, NeuralX, 34000, Montpellier, France.

Yassine Mamou (Y)

R&D, NeuralX, 34000, Montpellier, France.

Quentin Ceyrat (Q)

Nuclear Imaging Department, CHU de Bordeaux, 33000, Bordeaux, France.
Centre Imagerie Fonctionnelle, 33000, Bordeaux, France.

Laurence Bordenave (L)

Nuclear Imaging Department, CHU de Bordeaux, 33000, Bordeaux, France.

Pierre Coste (P)

Cardiology Department, CHU de Bordeaux, 33000, Bordeaux, France.

Jean-Baptiste Pinaquy (JB)

Nuclear Imaging Department, CHU de Bordeaux, 33000, Bordeaux, France.

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