Toxic epidermal necrolysis-like acute cutaneous lupus erythematosus: two cases report.
Acute cutaneous lupus erythematosus
TEN-like ACLE
case report
toxic epidermal necrolysis
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2021
2021
Historique:
received:
05
12
2020
accepted:
25
01
2021
entrez:
28
5
2021
pubmed:
29
5
2021
medline:
9
6
2021
Statut:
epublish
Résumé
Toxic epidermal necrolysis-like acute cutaneous lupus erythematosus (TEN-like ACLE) is a rare manifestation of systemic lupus erythematosus (SLE). Because of its rarity, little is known about this entity. In this report, we describe a case of two women previously diagnosed with SLE that presented TEN-like skin lesions. The common elements in both patients were the initial disposition of the lesions on the photoexposed areas, the positivity of Nikolsky´s sign, the discrete mucosal attrition compared to that observed during TEN, and the simultaneous appearance of dermatological lesions with an extra-cutaneous flare of lupus disease. The skin biopsy in both cases showed epidermal necrosis with an identification of lupus band on direct immunofluorescence. Systemic corticosteroids were used with a good evolution after 2 weeks. Skin damage is an indicator of disease activity, and careful search for extracutaneous involvement is obligatory to prevent further complications.
Identifiants
pubmed: 34046141
doi: 10.11604/pamj.2021.38.236.27303
pii: PAMJ-38-236
pmc: PMC8140758
doi:
Substances chimiques
Adrenal Cortex Hormones
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
236Informations de copyright
Copyright: Asmae Abdelmouttalib et al.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
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