Second passage of chronic wasting disease of mule deer to sheep by intracranial inoculation compared to classical scrapie.
PrPSc proteins
chronic wasting disease
deer
prions
scrapie
sheep
Journal
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
ISSN: 1943-4936
Titre abrégé: J Vet Diagn Invest
Pays: United States
ID NLM: 9011490
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
pubmed:
29
5
2021
medline:
14
7
2021
entrez:
28
5
2021
Statut:
ppublish
Résumé
The origin of chronic wasting disease (CWD) in cervids is unclear. One hypothesis suggests that CWD originated from scrapie in sheep. We compared the disease phenotype of sheep-adapted CWD to classical scrapie in sheep. We inoculated sheep intracranially with brain homogenate from first-passage mule deer CWD in sheep (sCWD
Identifiants
pubmed: 34047228
doi: 10.1177/10406387211017615
pmc: PMC8229824
doi:
Substances chimiques
Prion Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
711-720Références
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