Engineering of Extracellular Vesicles Based on Payload Changes for Tissue Regeneration.
Engineering
Extracellular vesicle
Medicine
Mesenchymal stem cell
Regeneration
Journal
Tissue engineering and regenerative medicine
ISSN: 2212-5469
Titre abrégé: Tissue Eng Regen Med
Pays: Korea (South)
ID NLM: 101699923
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
received:
23
03
2021
accepted:
19
04
2021
revised:
14
04
2021
pubmed:
30
5
2021
medline:
18
9
2021
entrez:
29
5
2021
Statut:
ppublish
Résumé
In the field of tissue regeneration and tissue engineering, many years ago, various nano to macroscopic-sized materials have been used to reduce inflammation and restore damaged tissue. Whether it is safe to study the regeneration of all tissues based on the biological mechanisms of an organism composed of cells is still debated, and studies using extracellular vesicles derived from cells have become popular in the past decade. It has been reported that exosomes with a size of 100 nm or less, which plays an important role in cell-cell communication, contain various factors, such as proliferation, anti-inflammatory, and growth factors. In addition, the payload of exosomes varies depending on the parent cell and the recipient cell, and a technology to differentiate the selective payload must treat specific diseases. In this review, we examined the current trends in research using exosomes derived from cells or tissues and analyzed various research reports on factors that can affect tissue regeneration.
Identifiants
pubmed: 34050888
doi: 10.1007/s13770-021-00349-w
pii: 10.1007/s13770-021-00349-w
pmc: PMC8325730
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
485-497Subventions
Organisme : Korea Health Industry Development Institute (KR)
ID : HI19C1334
Informations de copyright
© 2021. The Korean Tissue Engineering and Regenerative Medicine Society.
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