Disposable electrochemical glucose sensor based on water-soluble quinone-based mediators with flavin adenine dinucleotide-dependent glucose dehydrogenase.

Biosensing Techniques Flavin-Adenine Dinucleotide Glucose Glucose 1-Dehydrogenase Water
Disposable sensor Glucose dehydrogenase Glucose diffusion Quinone Self-monitoring blood glucose device

Journal

Biosensors & bioelectronics
ISSN: 1873-4235
Titre abrégé: Biosens Bioelectron
Pays: England
ID NLM: 9001289

Informations de publication

Date de publication:
01 Oct 2021
Historique:
received: 19 03 2021
revised: 14 05 2021
accepted: 16 05 2021
pubmed: 30 5 2021
medline: 22 6 2021
entrez: 29 5 2021
Statut: ppublish

Résumé

Glucose level measurement is essential for the point-of-care diagnosis, primarily for persons with diabetes. A disposable electrochemical glucose sensor is constructed using flavin adenine dinucleotide-dependent glucose dehydrogenase (FAD-GDH) and redox mediator for electron transfer from the enzyme to the electrode surface. Ideally, a suitable mediator should have high water solubility, high kinetic constant, high stability, and redox potential between -0.2 and 0.1 V vs. Ag|AgCl|sat. KCl. We designed and synthesized two new quinone-based water-soluble mediators: quinoline-5,8-dione (QD) and isoquinoline-5,8-dione (IQD). The formal potentials for both QD and IQD at pH 7.0 were -0.07 V vs. Ag|AgCl|sat. KCl. The logarithms of the electron exchange rate constants (k

Identifiants

DOI: 10.1016/j.bios.2021.113357 PMID: 34051384
pubmed: 34051384
pii: S0956-5663(21)00394-8
doi: 10.1016/j.bios.2021.113357
pii:
doi:

Substances chimiques

Water 059QF0KO0R
Flavin-Adenine Dinucleotide 146-14-5
Glucose 1-Dehydrogenase EC 1.1.1.47
Glucose IY9XDZ35W2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

113357

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Jannatul Morshed (J)

Division of Material Science, Faculty of Pure and Applied Science, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-5358, Japan.

Ryo Nakagawa (R)

Graduate School of Natural Science and Technology, Okayama University, Tsushimanaka, Kita, Okayama, 700-8530, Japan.

Motaher M Hossain (MM)

Division of Material Science, Faculty of Pure and Applied Science, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-5358, Japan.

Yuta Nishina (Y)

Graduate School of Natural Science and Technology, Okayama University, Tsushimanaka, Kita, Okayama, 700-8530, Japan.

Seiya Tsujimura (S)

Division of Material Science, Faculty of Pure and Applied Science, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-5358, Japan. Electronic address: seiya@ims.tsukuba.ac.jp.

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Techniques de biocapteur › Disposable electrochemical glucose sensor...
questionsmedicales.fr › Facteurs biologiques › Pigments biologiques › Flavines › Riboflavine › Flavine adénine dinucléotide › Disposable electrochemical glucose sensor...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Disposable electrochemical glucose sensor...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Alcohol oxidoreductases › Carbohydrate dehydrogenases › Glucose dehydrogenases › Glucose 1-dehydrogenase › Disposable electrochemical glucose sensor...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Eau › Disposable electrochemical glucose sensor...