Genome sequences of antibiotic-resistant Escherichia coli isolated from veal calves in the USA.


Journal

Journal of global antimicrobial resistance
ISSN: 2213-7173
Titre abrégé: J Glob Antimicrob Resist
Pays: Netherlands
ID NLM: 101622459

Informations de publication

Date de publication:
09 2021
Historique:
received: 30 10 2020
revised: 08 04 2021
accepted: 20 04 2021
pubmed: 31 5 2021
medline: 26 10 2021
entrez: 30 5 2021
Statut: ppublish

Résumé

The aim of this study was to describe the genome sequences of 38 antibiotic-resistant Escherichia coli isolated from veal calves. The isolates were recovered in 2015 from nine veal farms in the eastern USA and were screened for antibiotic susceptibility using an automated microdilution procedure. The draft genomes were sequenced on an Illumina NextSeq 500 platform and were assembled using SPAdes. In total, 294 resistance genes, categorised into 42 unique genes, conferring resistance to seven different antibiotic classes were detected. Extended-spectrum β-lactamase (ESBL) genes (bla The results of this study indicate a high level of diversity among multidrug-resistant E. coli isolates from veal operations. The identification of multiple isolates encoding resistance to β-lactams, macrolides and fluoroquinolones as well as virulence factors responsible for human infections warrants more study on the ecology of antibiotic resistance in veal operations.

Identifiants

pubmed: 34052521
pii: S2213-7165(21)00123-5
doi: 10.1016/j.jgar.2021.04.024
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
beta-Lactamases EC 3.5.2.6

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

69-73

Informations de copyright

Copyright © 2021. Published by Elsevier Ltd.

Auteurs

Seon Woo Kim (SW)

Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD, USA.

Jo Ann S Van Kessel (JAS)

Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD, USA.

Bradd J Haley (BJ)

Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD, USA. Electronic address: bradd.haley@usda.gov.

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Classifications MeSH