Protective effects of carbonic anhydrase inhibition in brain ischaemia
Carbonic anhydrase inhibitors
anoxic depolarisation
cerebral ischaemia
middle cerebral artery occlusion
synaptic potentials
Journal
Journal of enzyme inhibition and medicinal chemistry
ISSN: 1475-6374
Titre abrégé: J Enzyme Inhib Med Chem
Pays: England
ID NLM: 101150203
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
entrez:
31
5
2021
pubmed:
1
6
2021
medline:
24
8
2021
Statut:
ppublish
Résumé
Ischaemic stroke is a leading cause of death and disability. One of the major pathogenic mechanisms after ischaemia includes the switch to the glycolytic pathway, leading to tissue acidification. Carbonic anhydrase (CA) contributes to pH regulation. A new generation of CA inhibitors, AN11-740 and AN6-277 and the reference compound acetazolamide (ACTZ) were investigated in two models of brain ischaemia: in rat hippocampal acute slices exposed to severe oxygen, glucose deprivation (OGD) and in an
Identifiants
pubmed: 34056989
doi: 10.1080/14756366.2021.1907575
pmc: PMC8168743
doi:
Substances chimiques
Carbonic Anhydrase Inhibitors
0
Neuroprotective Agents
0
Carbonic Anhydrases
EC 4.2.1.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
964-976Références
Glia. 2006 Feb;53(3):241-7
pubmed: 16265666
Brain Res. 1999 Sep 18;842(1):148-58
pubmed: 10526105
Biochem Pharmacol. 2007 Sep 1;74(5):768-79
pubmed: 17626785
Neurochem Res. 2016 Apr;41(4):707-14
pubmed: 26586406
J Neurochem. 2006 Jun;97(5):1357-68
pubmed: 16696848
Metabolites. 2017 Sep 16;7(3):
pubmed: 28926956
J Neurochem. 2007 Jun;101(5):1400-13
pubmed: 17459147
Trends Neurosci. 1999 Sep;22(9):391-7
pubmed: 10441299
J Neurosci. 2000 Nov 15;20(22):8247-53
pubmed: 11069930
Exp Neurol. 2017 Sep;295:144-154
pubmed: 28602832
J Vis Exp. 2012 Nov 06;(69):
pubmed: 23168377
Metabolites. 2020 Oct 14;10(10):
pubmed: 33066524
Stroke. 1995 Apr;26(4):636-42; discussion 643
pubmed: 7709411
Br J Pharmacol. 2009 Jul;157(5):818-30
pubmed: 19422385
Am J Med. 2000 Mar;108(4):317-30
pubmed: 11014725
J Cereb Blood Flow Metab. 2013 Sep;33(9):1355-61
pubmed: 23756694
J Enzyme Inhib Med Chem. 2019 Dec;34(1):510-518
pubmed: 30688123
Front Neurosci. 2019 Dec 06;13:1301
pubmed: 31866811
J Cereb Blood Flow Metab. 2008 Feb;28(2):251-62
pubmed: 17971792
J Med Chem. 2016 Dec 8;59(23):10692-10704
pubmed: 27933963
Neurochem Int. 2003 Jul;43(1):9-17
pubmed: 12605878
J Biol Chem. 2006 Aug 18;281(33):23482-91
pubmed: 16790428
J Neurophysiol. 1997 Aug;78(2):891-902
pubmed: 9307122
Neurobiol Dis. 2010 Feb;37(2):259-66
pubmed: 19931616
J Enzyme Inhib Med Chem. 2009 Apr;24 Suppl 1:1-39
pubmed: 19330638
Prog Neurobiol. 2014 Apr;115:246-69
pubmed: 24407111
Front Pharmacol. 2018 Apr 24;9:399
pubmed: 29740323
PLoS One. 2012;7(9):e45250
pubmed: 23028880
J Cereb Blood Flow Metab. 1994 Jan;14(1):12-9
pubmed: 8263047
J Neurochem. 1993 Jul;61(1):284-9
pubmed: 8515275
Lancet. 2003 Sep 27;362(9389):1007-8
pubmed: 14522526
Stroke. 1986 Nov-Dec;17(6):1129-37
pubmed: 3810711
J Hirnforsch. 1981;22(1):47-57
pubmed: 7240726
Cereb Cortex. 2001 Mar;11(3):249-59
pubmed: 11230096
Nat Rev Drug Discov. 2008 Feb;7(2):168-81
pubmed: 18167490
Brain Res. 2006 Feb 16;1073-1074:470-80
pubmed: 16443200
J Enzyme Inhib Med Chem. 2021 Dec;36(1):561-580
pubmed: 33615947
Br J Pharmacol. 2006 Mar;147(5):524-32
pubmed: 16415905
Nat Rev Drug Discov. 2011 Sep 16;10(10):767-77
pubmed: 21921921
Expert Opin Ther Pat. 2018 Oct;28(10):713-721
pubmed: 30175635
J Enzyme Inhib Med Chem. 2016 Dec;31(6):894-9
pubmed: 26607399
Cancer Metastasis Rev. 2007 Jun;26(2):299-310
pubmed: 17415526
Circulation. 2007 May 22;115(20):e478-534
pubmed: 17515473
J Neurosci Methods. 2001 Jul 15;108(1):71-83
pubmed: 11459620
Stroke. 1999 Nov;30(11):2448-54; discussion 2455
pubmed: 10548683
Int Rev Neurobiol. 2014;119:309-48
pubmed: 25175971
Neuron. 2014 Jan 22;81(2):314-20
pubmed: 24462096
Nature. 2000 Oct 12;407(6805):802-9
pubmed: 11048732
J Biol Chem. 1971 Apr 25;246(8):2561-73
pubmed: 4994926
J Cereb Blood Flow Metab. 1996 Mar;16(2):214-20
pubmed: 8594052
Dialogues Clin Neurosci. 2009;11(3):281-95
pubmed: 19877496
Eur J Med Chem. 2012 Aug;54:470-82
pubmed: 22704999
J Cereb Blood Flow Metab. 1991 Jul;11(4):597-9
pubmed: 1904880
Br J Pharmacol. 2005 Jan;144(2):293-9
pubmed: 15665865
J Cereb Blood Flow Metab. 1996 May;16(3):367-77
pubmed: 8621741
J Cereb Blood Flow Metab. 1981;1(2):155-85
pubmed: 6276420
Neurotherapeutics. 2011 Jul;8(3):349-60
pubmed: 21671123
Brain Res. 2014 Mar 10;1551:59-72
pubmed: 24457041
Autophagy. 2010 Aug;6(6):738-53
pubmed: 20574158
Nat Med. 2008 May;14(5):497-500
pubmed: 18463660
Stroke. 2001 Nov;32(11):2682-8
pubmed: 11692034
Br J Pharmacol. 2003 Sep;140(2):305-14
pubmed: 12970092
Brain Res. 1990 Oct 15;530(1):138-41
pubmed: 2176914
Cancer Res. 2000 Dec 15;60(24):7075-83
pubmed: 11156414
J Enzyme Inhib Med Chem. 2015;30(5):689-721
pubmed: 25347767
Med Res Rev. 2020 Nov;40(6):2485-2565
pubmed: 32691504
Neurochem Int. 2008 May;52(6):905-19
pubmed: 18061308
Physiol Rev. 2001 Jul;81(3):1065-96
pubmed: 11427692