Alessio Nocentini

Affiliations
  • Università degli Studi di Firenze, Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Sesto Fiorentino, Italy;
ORCID: http://orcid.org/0000-0003-3342-702X

Publications (75)

Activation studies of the β-carbonic anhydrases from

Journal of enzyme inhibition and medicinal chemistry
Avec: Alessio Nocentini , Sonia Del Prete , Margaret D Mastrolorenzo , William A Donald , Clemente Capasso , Claudiu T Supuran

Discovery of New 1,1'-Biphenyl-4-sulfonamides as Selective Subnanomolar Human Carbonic Anhydrase II Inhibitors.

ACS medicinal chemistry letters
Avec: Giuseppe La Regina , Michela Puxeddu , Marianna Nalli , Daniela Vullo , Paola Gratteri , Claudiu Trandafir Supuran , Alessio Nocentini , Romano Silvestri

Halogenated isophthalamides and dipicolineamides: the role of the halogen substituents in the anion binding properties.

Dalton transactions (Cambridge, England : 2003)
Avec: Giacomo Picci , Carla Bazzicalupi , Simon J Coles , Paola Gratteri , Francesco Isaia , Vito Lippolis , Riccardo Montis , Sergio Murgia , Alessio Nocentini , James B Orton , Claudia Caltagirone

Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy.

Journal of medicinal chemistry
Avec: Alessio Nocentini , Vincenzo Alterio , Silvia Bua , Laura Micheli , Davide Esposito , Martina Buonanno , Gianluca Bartolucci , Sameh M Osman , Zeid A ALOthman , Roberto Cirilli , Marco Pierini , Simona Maria Monti , Lorenzo Di Cesare Mannelli , Paola Gratteri , Carla Ghelardini , Giuseppina De Simone , Claudiu T Supuran

Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action.

Journal of medicinal chemistry
Avec: Mohamed Fares , Wagdy M Eldehna , Silvia Bua , Cecilia Lanzi , Laura Lucarini , Emanuela Masini , Thomas S Peat , Hatem A Abdel-Aziz , Alessio Nocentini , Paul A Keller , Claudiu T Supuran

4-Substituted benzenesulfonamides featuring cyclic imides moieties exhibit potent and isoform-selective carbonic anhydrase II/IX inhibition.

Bioorganic chemistry
Avec: Alaa A-M Abdel-Aziz , Adel S El-Azab , Adel H Ghiaty , Paola Gratteri , Claudiu T Supuran , Alessio Nocentini

Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity.

Bioorganic chemistry
Avec: Wagdy M Eldehna , Mohamed A Abdelrahman , Alessio Nocentini , Silvia Bua , Sara T Al-Rashood , Ghada S Hassan , Alessandro Bonardi , Abdulrahman A Almehizia , Hamad M Alkahtani , Amal Alharbi , Paola Gratteri , Claudiu T Supuran

β3-Adrenoreceptor Activity Limits Apigenin Efficacy in Ewing Sarcoma Cells: A Dual Approach to Prevent Cell Survival.

International journal of molecular sciences
Avec: Amada Pasha , Marina Vignoli , Angela Subbiani , Alessio Nocentini , Silvia Selleri , Paola Gratteri , Annalisa Dabraio , Tommaso Casini , Luca Filippi , Ilaria Fotzi , Claudio Favre , Maura Calvani

Synthesis and comparative carbonic anhydrase inhibition of new Schiff's bases incorporating benzenesulfonamide, methanesulfonamide, and methylsulfonylbenzene scaffolds.

Bioorganic chemistry
Avec: Adel S El-Azab , Alaa A-M Abdel-Aziz , Silvia Bua , Alessio Nocentini , Mohammed M Alanazi , Nawaf A AlSaif , Ibrahim A Al-Suwaidan , Mohamed M Hefnawy , Claudiu T Supuran

Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from

Journal of enzyme inhibition and medicinal chemistry
Avec: Alessio Nocentini , Sameh M Osman , Igor A Almeida , Veronica Cardoso , Fatmah Ali S Alasmary , Zeid AlOthman , Alane B Vermelho , Paola Gratteri , Claudiu T Supuran

Safety effects of automated section speed control on the Italian motorway network.

Journal of safety research
Avec: Francesca La Torre , Monica Meocci , Alessandro Nocentini

Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment.

European journal of medicinal chemistry
Avec: Mikhail Krasavin , Anton Shetnev , Tatyana Sharonova , Sergey Baykov , Stanislav Kalinin , Alessio Nocentini , Vladimir Sharoyko , Giulio Poli , Tiziano Tuccinardi , Sofia Presnukhina , Tatiana B Tennikova , Claudiu T Supuran

For Whom Is Anti-Bullying Intervention Most Effective? The Role of Temperament.

International journal of environmental research and public health
Avec: Annalaura Nocentini , Benedetta Emanuela Palladino , Ersilia Menesini

Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase.

Journal of enzyme inhibition and medicinal chemistry
Avec: Alessio Nocentini , Andrea Angeli , Fabrizio Carta , Jean-Yves Winum , Raivis Zalubovskis , Simone Carradori , Clemente Capasso , William A Donald , Claudiu T Supuran

Benzoxaboroles: New Potent Inhibitors of the Carbonic Anhydrases of the Pathogenic Bacterium

ACS medicinal chemistry letters
Avec: Alessandro Bonardi , Alessio Nocentini , Roberta Cadoni , Sonia Del Prete , Pascal Dumy , Clemente Capasso , Paola Gratteri , Claudiu T Supuran , Jean-Yves Winum

Mapping community, social, and economic risks to investigate the association with school violence and bullying in Italy.

Child abuse & neglect
Avec: Carlo Tramontano , Annalaura Nocentini , Laura Palmerio , Bruno Losito , Ersilia Menesini

Small-molecule CD73 inhibitors for the immunotherapy of cancer: a patent and literature review (2017-present).

Expert opinion on therapeutic patents
Avec: Alessio Nocentini , Clemente Capasso , Claudiu T Supuran

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors.

Journal of enzyme inhibition and medicinal chemistry
Avec: Adel S El-Azab , Alaa A-M Abdel-Aziz , Silvia Bua , Alessio Nocentini , Nawaf A AlSaif , Mohammed M Alanazi , Manal A El-Gendy , Hany E A Ahmed , Claudiu T Supuran

Drug Screening in Human Cells by NMR Spectroscopy Allows the Early Assessment of Drug Potency.

Angewandte Chemie (International ed. in English)
Avec: Enrico Luchinat , Letizia Barbieri , Matteo Cremonini , Alessio Nocentini , Claudiu T Supuran , Lucia Banci

Extending the Inhibition Profiles of Coumarin-Based Compounds Against Human Carbonic Anhydrases: Synthesis, Biological, and In Silico Evaluation.

Molecules (Basel, Switzerland)
Avec: Victor Kartsev , Athina Geronikaki , Silvia Bua , Alessio Nocentini , Anthi Petrou , Boris Lichitsky , Mykhaylo Frasinyuk , Janis Leitans , Andris Kazaks , Kaspars Tars , Claudiu T Supuran

Role of Carbonic Anhydrase in Cerebral Ischemia and Carbonic Anhydrase Inhibitors as Putative Protective Agents.

International journal of molecular sciences
Avec: Irene Bulli , Ilaria Dettori , Elisabetta Coppi , Federica Cherchi , Martina Venturini , Lorenzo Di Cesare Mannelli , Carla Ghelardini , Alessio Nocentini , Claudiu T Supuran , Anna Maria Pugliese , Felicita Pedata

Natural inspired piperine-based sulfonamides and carboxylic acids as carbonic anhydrase inhibitors: Design, synthesis and biological evaluation.

European journal of medicinal chemistry
Avec: Diaaeldin M Elimam , Abdullah A Elgazar , Alessandro Bonardi , Mohamed Abdelfadil , Alessio Nocentini , Ramadan A El-Domany , Hatem A Abdel-Aziz , Farid A Badria , Claudiu T Supuran , Wagdy M Eldehna

2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases.

Journal of enzyme inhibition and medicinal chemistry
Avec: Alma Fuentes-Aguilar , Penélope Merino-Montiel , Sara Montiel-Smith , Socorro Meza-Reyes , José Luis Vega-Báez , Adrián Puerta , Miguel X Fernandes , José M Padrón , Andrea Petreni , Alessio Nocentini , Claudiu T Supuran , Óscar López , José G Fernández-Bolaños

Structure-activity relationship studies for inhibitors for vancomycin-resistant

Journal of enzyme inhibition and medicinal chemistry
Avec: Weiwei An , Katrina J Holly , Alessio Nocentini , Ryan D Imhoff , Chad S Hewitt , Nader S Abutaleb , Xufeng Cao , Mohamed N Seleem , Claudiu T Supuran , Daniel P Flaherty

Pathways to resilience: The parallel change in children's emotional difficulties and family context during the COVID-19 lockdown in Italy.

Psychological trauma : theory, research, practice and policy
Avec: Annalaura Nocentini , Benedetta Emanuela Palladino , Enrico Imbimbo , Ersilia Menesini

Non-Suicidal Self-Injury in Adolescence: The Role of Pre-Existing Vulnerabilities and COVID-19-Related Stress.

Journal of youth and adolescence
Avec: Lisa De Luca , Matteo Giletta , Annalaura Nocentini , Ersilia Menesini

3

Journal of enzyme inhibition and medicinal chemistry
Avec: Aleksandrs Pustenko , Anastasija Balašova , Alessio Nocentini , Claudiu T Supuran , Raivis Žalubovskis

Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights.

Journal of enzyme inhibition and medicinal chemistry
Avec: Waleed A Badawi , Mahmoud Rashed , Alessio Nocentini , Alessandro Bonardi , Mohammad M Abd-Alhaseeb , Sara T Al-Rashood , Giri Babu Veerakanellore , Taghreed A Majrashi , Eslam B Elkaeed , Bahaa Elgendy , Paola Gratteri , Claudiu T Supuran , Wagdy M Eldehna , Mohamed Elagawany

Pyrrolyl and Indolyl α-γ-Diketo Acid Derivatives Acting as Selective Inhibitors of Human Carbonic Anhydrases IX and XII.

Pharmaceuticals (Basel, Switzerland)
Avec: Davide Ialongo , Antonella Messore , Valentina Noemi Madia , Valeria Tudino , Alessio Nocentini , Paola Gratteri , Simone Giovannuzzi , Claudiu T Supuran , Alice Nicolai , Susanna Scarpa , Samanta Taurone , Michele Camarda , Marco Artico , Veronica Papa , Francesco Saccoliti , Luigi Scipione , Roberto Di Santo , Roberta Costi

Selective carbonic anhydrase IX and XII inhibitors based around a functionalized coumarin scaffold.

Drug development research
Avec: Bader I Huwaimel , Sravan K Jonnalagadda , Shirisha Jonnalagadda , Shikha Kumari , Alessio Nocentini , Claudiu T Supuran , Paul C Trippier

Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant

International journal of molecular sciences
Avec: Silvia Bua , Alessandro Bonardi , Georgiana Ramona Mük , Alessio Nocentini , Paola Gratteri , Claudiu T Supuran

Dual Inhibitors of Brain Carbonic Anhydrases and Monoamine Oxidase-B Efficiently Protect against Amyloid-β-Induced Neuronal Toxicity, Oxidative Stress, and Mitochondrial Dysfunction.

Journal of medicinal chemistry
Avec: Simone Giovannuzzi , Daniel Chavarria , Gustavo Provensi , Manuela Leri , Monica Bucciantini , Simone Carradori , Alessandro Bonardi , Paola Gratteri , Fernanda Borges , Alessio Nocentini , Claudiu T Supuran

Novel Diamide-Based Benzenesulfonamides as Selective Carbonic Anhydrase IX Inhibitors Endowed with Antitumor Activity: Synthesis, Biological Evaluation and In Silico Insights.

International journal of molecular sciences
Avec: Mohamed A Abdelrahman , Wagdy M Eldehna , Alessio Nocentini , Silvia Bua , Sara T Al-Rashood , Ghada S Hassan , Alessandro Bonardi , Abdulrahman A Almehizia , Hamad M Alkahtani , Amal Alharbi , Paola Gratteri , Claudiu T Supuran

Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative.

Journal of enzyme inhibition and medicinal chemistry
Avec: David Bibi , Bella Shusterman , Alessio Nocentini , Claudiu T Supuran , Meir Bialer

Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and

Journal of enzyme inhibition and medicinal chemistry
Avec: Mohamed A Abdelrahman , Wagdy M Eldehna , Alessio Nocentini , Hany S Ibrahim , Hadia Almahli , Hatem A Abdel-Aziz , Sahar M Abou-Seri , Claudiu T Supuran

Click-tailed benzenesulfonamides as potent bacterial carbonic anhydrase inhibitors for targeting Mycobacterium tuberculosis and Vibrio cholerae.

Bioorganic chemistry
Avec: Silvia Bua , Sameh M Osman , Sonia Del Prete , Clemente Capasso , Zeid AlOthman , Alessio Nocentini , Claudiu T Supuran

Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents.

European journal of medicinal chemistry
Avec: Wagdy M Eldehna , Mahmoud F Abo-Ashour , Alessio Nocentini , Radwan S El-Haggar , Silvia Bua , Alessandro Bonardi , Sara T Al-Rashood , Ghada S Hassan , Paola Gratteri , Hatem A Abdel-Aziz , Claudiu T Supuran

Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation.

European journal of medicinal chemistry
Avec: Mohamed A Said , Wagdy M Eldehna , Alessio Nocentini , Samar H Fahim , Alessandro Bonardi , Abdullah A Elgazar , Vladimír Kryštof , Dalia H Soliman , Hatem A Abdel-Aziz , Paola Gratteri , Sahar M Abou-Seri , Claudiu T Supuran

Benzimidazole derivatives as potent and isoform selective tumor-associated carbonic anhydrase IX/XII inhibitors.

Bioorganic chemistry
Avec: Azize Gizem Uslu , Tuğçe Gür Maz , Alessio Nocentini , Erden Banoglu , Claudiu T Supuran , Burcu Çalışkan

The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors.

Journal of enzyme inhibition and medicinal chemistry
Avec: Aleksandrs Pustenko , Alessio Nocentini , Paola Gratteri , Alessandro Bonardi , Igor Vozny , Raivis Žalubovskis , Claudiu T Supuran

Structural and biochemical characterization of novel carbonic anhydrases from Phaeodactylum tricornutum.

Acta crystallographica. Section D, Structural biology
Avec: Shengyang Jin , Daniela Vullo , Silvia Bua , Alessio Nocentini , Claudiu T Supuran , Yong Gui Gao

The role of carbonic anhydrases in extinction of contextual fear memory.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Scheila Daiane Schmidt , Alessia Costa , Barbara Rani , Eduarda Godfried Nachtigall , Maria Beatrice Passani , Fabrizio Carta , Alessio Nocentini , Jociane de Carvalho Myskiw , Cristiane Regina Guerino Furini , Claudiu T Supuran , Ivan Izquierdo , Patrizio Blandina , Gustavo Provensi

Peer victimization and developmental psychopathology in childhood and adolescence Italian psychiatric emergency unit. A single center retrospective observational study.

Psychology, health & medicine
Avec: Tiziana Pisano , Sara Gori , Lisa De Luca , Giada Fiorentini , Sara Minghetti , Annalaura Nocentini , Ersilia Menesini

3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies.

European journal of medicinal chemistry
Avec: Abdulsalam A M Alkhaldi , Mohammad M Al-Sanea , Alessio Nocentini , Wagdy M Eldehna , Zainab M Elsayed , Alessandro Bonardi , Mahmoud F Abo-Ashour , Ashraf K El-Damasy , Mohammed S Abdel-Maksoud , Tarfah Al-Warhi , Paola Gratteri , Hatem A Abdel-Aziz , Claudiu T Supuran , Radwan El-Haggar

Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors.

Bioorganic chemistry
Avec: Davide Moi , Alessio Nocentini , Alessandro Deplano , Sameh M Osman , Zeid A AlOthman , Valentina Piras , Gianfranco Balboni , Claudiu T Supuran , Valentina Onnis

Coping Power Universal for middle school students: The first efficacy study.

Journal of adolescence
Avec: Pietro Muratori , Iacopo Bertacchi , Gennaro Catone , Francesca Mannucci , Annalaura Nocentini , Simone Pisano , John E Lochman

Benzothiazole derivatives as anticancer agents.

Journal of enzyme inhibition and medicinal chemistry
Avec: Ali Irfan , Fozia Batool , Syeda Andleeb Zahra Naqvi , Amjad Islam , Sameh M Osman , Alessio Nocentini , Siham A Alissa , Claudiu T Supuran

Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure.

Bioorganic & medicinal chemistry
Avec: Stanislav Kalinin , Annika Valtari , Marika Ruponen , Elisa Toropainen , Alexander Kovalenko , Alessio Nocentini , Maxim Gureev , Dmitry Dar'in , Arto Urtti , Claudiu T Supuran , Mikhail Krasavin

Inclusion of a 5-fluorouracil moiety in nitrogenous bases derivatives as human carbonic anhydrase IX and XII inhibitors produced a targeted action against MDA-MB-231 and T47D breast cancer cells.

European journal of medicinal chemistry
Avec: Andrea Petreni , Alessandro Bonardi , Carrie Lomelino , Sameh M Osman , Zeid A ALOthman , Wagdy M Eldehna , Radwan El-Haggar , Robert McKenna , Alessio Nocentini , Claudiu T Supuran

Validation of the Proposed Specifiers for Conduct Disorder (PSCD) Scale in a Sample of Italian Students.

Children (Basel, Switzerland)
Avec: Pietro Muratori , Carlo Buonanno , Anna Gallani , Giuseppe Grossi , Valentina Levantini , Annarita Milone , Simone Pisano , Randall T Salekin , Gianluca Sesso , Gabriele Masi , Annalaura Nocentini

An overview on the recently discovered iota-carbonic anhydrases.

Journal of enzyme inhibition and medicinal chemistry
Avec: Alessio Nocentini , Claudiu T Supuran , Clemente Capasso

Identification of N-phenyl-2-(phenylsulfonyl)acetamides/propanamides as new SLC-0111 analogues: Synthesis and evaluation of the carbonic anhydrase inhibitory activities.

European journal of medicinal chemistry
Avec: Mostafa M Elbadawi , Wagdy M Eldehna , Alessio Nocentini , Mahmoud F Abo-Ashour , Eslam B Elkaeed , Mohamed A Abdelgawad , Khalid S Alharbi , Hatem A Abdel-Aziz , Claudiu T Supuran , Paola Gratteri , Mohammad M Al-Sanea

Synthesis and Enantioselective Pharmacokinetic/Pharmacodynamic Analysis of New CNS-Active Sulfamoylphenyl Carbamate Derivatives.

International journal of molecular sciences
Avec: Reem Odi , David Bibi , Bella Shusterman , Natalia Erenburg , Chanan Shaul , Claudiu T Supuran , Alessio Nocentini , Meir Bialer

Development of novel benzofuran-based SLC-0111 analogs as selective cancer-associated carbonic anhydrase isoform IX inhibitors.

European journal of medicinal chemistry
Avec: Moataz Shaldam , Wagdy M Eldehna , Alessio Nocentini , Zainab M Elsayed , Tamer M Ibrahim , Rofaida Salem , Ramadan A El-Domany , Clemente Capasso , Hatem A Abdel-Aziz , Claudiu T Supuran

Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators.

Journal of enzyme inhibition and medicinal chemistry
Avec: Alessio Nocentini , Doretta Cuffaro , Lidia Ciccone , Elisabetta Orlandini , Susanna Nencetti , Elisa Nuti , Armando Rossello , Claudiu T Supuran

Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion.

European journal of medicinal chemistry
Avec: Abdeslem Bouzina , Malika Berredjem , Alessio Nocentini , Silvia Bua , Zouhair Bouaziz , Joachim Jose , Marc Le Borgne , Christelle Marminon , Paola Gratteri , Claudiu T Supuran

Protease inhibitors targeting the main protease and papain-like protease of coronaviruses.

Expert opinion on therapeutic patents
Avec: Clemente Capasso , Alessio Nocentini , Claudiu T Supuran

Protective effects of carbonic anhydrase inhibition in brain ischaemia

Journal of enzyme inhibition and medicinal chemistry
Avec: Ilaria Dettori , Irene Fusco , Irene Bulli , Lisa Gaviano , Elisabetta Coppi , Federica Cherchi , Martina Venturini , Lorenzo Di Cesare Mannelli , Carla Ghelardini , Alessio Nocentini , Claudiu T Supuran , Anna Maria Pugliese , Felicita Pedata

Pharmaceutical strategies for preventing toxicity and promoting antioxidant and anti-inflammatory actions of bilirubin.

Journal of enzyme inhibition and medicinal chemistry
Avec: Alessio Nocentini , Alessandro Bonardi , Simone Pratesi , Paola Gratteri , Carlo Dani , Claudiu T Supuran

Calixarenes Incorporating Sulfonamide Moieties: Versatile Ligands for Carbonic Anhydrases Inhibition.

Chemistry (Weinheim an der Bergstrasse, Germany)
Avec: Davide Sbravati , Alessandro Bonardi , Silvia Bua , Andrea Angeli , Marta Ferraroni , Alessio Nocentini , Alessandro Casnati , Paola Gratteri , Francesco Sansone , Claudiu T Supuran

Computationally enhanced X-ray diffraction analysis of a gold(III) complex interacting with the human telomeric DNA G-quadruplex. Unravelling non-unique ligand positioning.

International journal of biological macromolecules
Avec: Damiano Cirri , Carla Bazzicalupi , Ulf Ryde , Justin Bergmann , Francesca Binacchi , Alessio Nocentini , Alessandro Pratesi , Paola Gratteri , Luigi Messori

Novel 3-(6-methylpyridin-2-yl)coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity.

Journal of enzyme inhibition and medicinal chemistry
Avec: Haytham O Tawfik , Moataz A Shaldam , Alessio Nocentini , Rofaida Salem , Hadia Almahli , Sara T Al-Rashood , Claudiu T Supuran , Wagdy M Eldehna

Diversely

Journal of enzyme inhibition and medicinal chemistry
Avec: Andrea Angeli , Marta Ferraroni , Alessandro Bonardi , Claudiu T Supuran , Alessio Nocentini

Leveraging SARS-CoV-2 Main Protease (M

International journal of molecular sciences
Avec: Viviana De Luca , Andrea Angeli , Alessio Nocentini , Paola Gratteri , Silvia Pratesi , Damiano Tanini , Vincenzo Carginale , Antonella Capperucci , Claudiu T Supuran , Clemente Capasso

Continued Structural Exploration of Sulfocoumarin as Selective Inhibitor of Tumor-Associated Human Carbonic Anhydrases IX and XII.

Molecules (Basel, Switzerland)
Avec: Simone Giovannuzzi , Clemente Capasso , Alessio Nocentini , Claudiu T Supuran

Development of Hydrogen Sulfide-Releasing Carbonic Anhydrases IX- and XII-Selective Inhibitors with Enhanced Antihyperalgesic Action in a Rat Model of Arthritis.

Journal of medicinal chemistry
Avec: Alessandro Bonardi , Laura Micheli , Lorenzo Di Cesare Mannelli , Carla Ghelardini , Paola Gratteri , Alessio Nocentini , Claudiu T Supuran

Development of potent nanosized carbonic anhydrase inhibitor for targeted therapy of hypoxic solid tumors.

International journal of pharmaceutics
Avec: Wagdy M Eldehna , Mahmoud A El Hassab , Nahla A Abdelshafi , Rana A Eissa , Nadeen H Diab , Ekram H Mohamed , Mamdouh A Oraby , Sara T Al-Rashood , Rana G Eissa , Zainab M Elsayed , Alessio Nocentini , Claudiu T Supuran , Mahmoud Elsabahy , Noura G Eissa

Chlorinated benzothiadiazines inhibit angiogenesis through suppression of VEGFR2 phosphorylation.

Bioorganic & medicinal chemistry
Avec: Bader I Huwaimel , Sravan Jonnalagadda , Shirisha Jonnalagadda , Fatema T Zahra , Alessio Nocentini , Claudiu T Supuran , Constantinos M Mikelis , Paul C Trippier

COVID-19 pandemic impact among adolescents with eating disorders referred to Italian psychiatric unit.

Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc
Avec: Pietro Cappelletto , Lisa De Luca , Benedetta Taddei , Silvia Taddei , Annalaura Nocentini , Tiziana Pisano

Development of novel organometallic sulfonamides with N-ethyl or N-methyl benzenesulfonamide units as potential human carbonic anhydrase I, II, IX and XII isoforms' inhibitors: Synthesis, biological evaluation and docking studies.

Journal of inorganic biochemistry
Avec: Miguel Gallardo , Rodrigo Arancibia , Claudiu T Supuran , Alessio Nocentini , David Villaman , Patricia M Toro , Michelle Muñoz-Osses , Carolina Mascayano

Enhanced Recognition Memory through Dual Modulation of Brain Carbonic Anhydrases and Cholinesterases.

Journal of medicinal chemistry
Avec: Alessio Nocentini , Alessia Costa , Alessandro Bonardi , Andrea Ammara , Simone Giovannuzzi , Andrea Petreni , Gianluca Bartolucci , Barbara Rani , Manuela Leri , Monica Bucciantini , José G Fernández-Bolaños , Óscar López , Maria Beatrice Passani , Gustavo Provensi , Paola Gratteri , Claudiu T Supuran

Inhibition survey with phenolic compounds against the δ- and η-class carbonic anhydrases from the marine diatom

Journal of enzyme inhibition and medicinal chemistry
Avec: Siham A Alissa , Hanan A Alghulikah , Zeid A ALOthman , Sameh M Osman , Sonia Del Prete , Clemente Capasso , Alessio Nocentini , Claudiu T Supuran

The Effect of Substituted Benzene-Sulfonamides and Clinically Licensed Drugs on the Catalytic Activity of CynT2, a Carbonic Anhydrase Crucial for

International journal of molecular sciences
Avec: Sonia Del Prete , Viviana De Luca , Silvia Bua , Alessio Nocentini , Vincenzo Carginale , Claudiu T Supuran , Clemente Capasso

Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action.

Journal of medicinal chemistry
Avec: Alessandro Bonardi , Alessio Nocentini , Silvia Bua , Jacob Combs , Carrie Lomelino , Jacob Andring , Laura Lucarini , Silvia Sgambellone , Emanuela Masini , Robert McKenna , Paola Gratteri , Claudiu T Supuran

Anion Inhibition Studies of the Beta-Carbonic Anhydrase from

Molecules (Basel, Switzerland)
Avec: Sonia Del Prete , Viviana De Luca , Alessio Nocentini , Andrea Scaloni , Margaret D Mastrolorenzo , Claudiu T Supuran , Clemente Capasso

Réseau de co-auteurs

Claudiu T Supuran 62 collaborations
Paola Gratteri 26 collaborations
Alessandro Bonardi 18 collaborations
Silvia Bua 15 collaborations
Wagdy M Eldehna 14 collaborations
Clemente Capasso 13 collaborations
Hatem A Abdel-Aziz 8 collaborations
Annalaura Nocentini 8 collaborations
Sameh M Osman 7 collaborations
Sonia Del Prete 6 collaborations
Sara T Al-Rashood 6 collaborations
Ersilia Menesini 5 collaborations
Lorenzo Di Cesare Mannelli 4 collaborations
Carla Ghelardini 4 collaborations
Andrea Angeli 4 collaborations
Simone Giovannuzzi 4 collaborations
Zeid A ALOthman 3 collaborations
Alaa A-M Abdel-Aziz 3 collaborations
Adel S El-Azab 3 collaborations
Mohamed A Abdelrahman 3 collaborations
Ghada S Hassan 3 collaborations
Andrea Petreni 3 collaborations
Lisa De Luca 3 collaborations
Gustavo Provensi 3 collaborations
Mahmoud F Abo-Ashour 3 collaborations
Zainab M Elsayed 3 collaborations
Viviana De Luca 3 collaborations
Margaret D Mastrolorenzo 2 collaborations
William A Donald 2 collaborations
Daniela Vullo 2 collaborations
Carla Bazzicalupi 2 collaborations
Laura Micheli 2 collaborations
Gianluca Bartolucci 2 collaborations
Laura Lucarini 2 collaborations
Emanuela Masini 2 collaborations
Abdulrahman A Almehizia 2 collaborations
Hamad M Alkahtani 2 collaborations
Amal Alharbi 2 collaborations
Mohammed M Alanazi 2 collaborations
Nawaf A AlSaif 2 collaborations
Zeid AlOthman 2 collaborations
Mikhail Krasavin 2 collaborations
Stanislav Kalinin 2 collaborations
Benedetta Emanuela Palladino 2 collaborations
Fabrizio Carta 2 collaborations
Jean-Yves Winum 2 collaborations
Simone Carradori 2 collaborations
Irene Bulli 2 collaborations
Ilaria Dettori 2 collaborations
Elisabetta Coppi 2 collaborations
Federica Cherchi 2 collaborations
Martina Venturini 2 collaborations
Anna Maria Pugliese 2 collaborations
Felicita Pedata 2 collaborations
Abdullah A Elgazar 2 collaborations
Ramadan A El-Domany 2 collaborations
Óscar López 2 collaborations
José G Fernández-Bolaños 2 collaborations
Aleksandrs Pustenko 2 collaborations
Raivis Žalubovskis 2 collaborations
Eslam B Elkaeed 2 collaborations
Bader I Huwaimel 2 collaborations
Shirisha Jonnalagadda 2 collaborations
Paul C Trippier 2 collaborations
Manuela Leri 2 collaborations
Monica Bucciantini 2 collaborations
David Bibi 2 collaborations
Bella Shusterman 2 collaborations
Meir Bialer 2 collaborations
Hadia Almahli 2 collaborations
Sahar M Abou-Seri 2 collaborations
Alessia Costa 2 collaborations
Barbara Rani 2 collaborations
Maria Beatrice Passani 2 collaborations
Tiziana Pisano 2 collaborations
Mohammad M Al-Sanea 2 collaborations
Radwan El-Haggar 2 collaborations
Pietro Muratori 2 collaborations
Simone Pisano 2 collaborations
Siham A Alissa 2 collaborations
Carrie Lomelino 2 collaborations
Robert McKenna 2 collaborations
Rofaida Salem 2 collaborations
Marta Ferraroni 2 collaborations
Vincenzo Carginale 2 collaborations
Giuseppe La Regina 1 collaboration
Michela Puxeddu 1 collaboration
Marianna Nalli 1 collaboration
Claudiu Trandafir Supuran 1 collaboration
Romano Silvestri 1 collaboration
Giacomo Picci 1 collaboration
Simon J Coles 1 collaboration
Francesco Isaia 1 collaboration
Vito Lippolis 1 collaboration
Riccardo Montis 1 collaboration
Sergio Murgia 1 collaboration
James B Orton 1 collaboration
Claudia Caltagirone 1 collaboration
Vincenzo Alterio 1 collaboration
Davide Esposito 1 collaboration
Martina Buonanno 1 collaboration
Roberto Cirilli 1 collaboration
Marco Pierini 1 collaboration
Simona Maria Monti 1 collaboration
Giuseppina De Simone 1 collaboration
Mohamed Fares 1 collaboration
Cecilia Lanzi 1 collaboration
Thomas S Peat 1 collaboration
Paul A Keller 1 collaboration
Adel H Ghiaty 1 collaboration
Amada Pasha 1 collaboration
Marina Vignoli 1 collaboration
Angela Subbiani 1 collaboration
Silvia Selleri 1 collaboration
Annalisa Dabraio 1 collaboration
Tommaso Casini 1 collaboration
Luca Filippi 1 collaboration
Ilaria Fotzi 1 collaboration
Claudio Favre 1 collaboration
Maura Calvani 1 collaboration
Ibrahim A Al-Suwaidan 1 collaboration
Mohamed M Hefnawy 1 collaboration
Igor A Almeida 1 collaboration
Veronica Cardoso 1 collaboration
Fatmah Ali S Alasmary 1 collaboration
Alane B Vermelho 1 collaboration
Francesca La Torre 1 collaboration
Monica Meocci 1 collaboration
Alessandro Nocentini 1 collaboration
Anton Shetnev 1 collaboration
Tatyana Sharonova 1 collaboration
Sergey Baykov 1 collaboration
Vladimir Sharoyko 1 collaboration
Giulio Poli 1 collaboration
Tiziano Tuccinardi 1 collaboration
Sofia Presnukhina 1 collaboration
Tatiana B Tennikova 1 collaboration
Raivis Zalubovskis 1 collaboration
Roberta Cadoni 1 collaboration
Pascal Dumy 1 collaboration
Carlo Tramontano 1 collaboration
Laura Palmerio 1 collaboration
Bruno Losito 1 collaboration
Manal A El-Gendy 1 collaboration
Hany E A Ahmed 1 collaboration
Enrico Luchinat 1 collaboration
Letizia Barbieri 1 collaboration
Matteo Cremonini 1 collaboration
Lucia Banci 1 collaboration
Victor Kartsev 1 collaboration
Athina Geronikaki 1 collaboration
Anthi Petrou 1 collaboration
Boris Lichitsky 1 collaboration
Mykhaylo Frasinyuk 1 collaboration
Janis Leitans 1 collaboration
Andris Kazaks 1 collaboration
Kaspars Tars 1 collaboration
Diaaeldin M Elimam 1 collaboration
Mohamed Abdelfadil 1 collaboration
Farid A Badria 1 collaboration
Alma Fuentes-Aguilar 1 collaboration
Penélope Merino-Montiel 1 collaboration
Sara Montiel-Smith 1 collaboration
Socorro Meza-Reyes 1 collaboration
José Luis Vega-Báez 1 collaboration
Adrián Puerta 1 collaboration
Miguel X Fernandes 1 collaboration
José M Padrón 1 collaboration
Weiwei An 1 collaboration
Katrina J Holly 1 collaboration
Ryan D Imhoff 1 collaboration
Chad S Hewitt 1 collaboration
Nader S Abutaleb 1 collaboration
Xufeng Cao 1 collaboration
Mohamed N Seleem 1 collaboration
Daniel P Flaherty 1 collaboration
Enrico Imbimbo 1 collaboration
Matteo Giletta 1 collaboration
Anastasija Balašova 1 collaboration
Waleed A Badawi 1 collaboration
Mahmoud Rashed 1 collaboration
Mohammad M Abd-Alhaseeb 1 collaboration
Giri Babu Veerakanellore 1 collaboration
Taghreed A Majrashi 1 collaboration
Bahaa Elgendy 1 collaboration
Mohamed Elagawany 1 collaboration
Davide Ialongo 1 collaboration
Antonella Messore 1 collaboration
Valentina Noemi Madia 1 collaboration
Valeria Tudino 1 collaboration
Alice Nicolai 1 collaboration
Susanna Scarpa 1 collaboration
Samanta Taurone 1 collaboration
Michele Camarda 1 collaboration
Marco Artico 1 collaboration
Veronica Papa 1 collaboration
Francesco Saccoliti 1 collaboration
Luigi Scipione 1 collaboration
Roberto Di Santo 1 collaboration
Roberta Costi 1 collaboration
Sravan K Jonnalagadda 1 collaboration
Shikha Kumari 1 collaboration
Georgiana Ramona Mük 1 collaboration
Daniel Chavarria 1 collaboration
Fernanda Borges 1 collaboration
Hany S Ibrahim 1 collaboration
Radwan S El-Haggar 1 collaboration
Mohamed A Said 1 collaboration
Samar H Fahim 1 collaboration
Vladimír Kryštof 1 collaboration
Dalia H Soliman 1 collaboration
Azize Gizem Uslu 1 collaboration
Tuğçe Gür Maz 1 collaboration
Erden Banoglu 1 collaboration
Burcu Çalışkan 1 collaboration
Igor Vozny 1 collaboration
Shengyang Jin 1 collaboration
Yong Gui Gao 1 collaboration
Scheila Daiane Schmidt 1 collaboration
Eduarda Godfried Nachtigall 1 collaboration
Jociane de Carvalho Myskiw 1 collaboration
Cristiane Regina Guerino Furini 1 collaboration
Ivan Izquierdo 1 collaboration
Patrizio Blandina 1 collaboration
Sara Gori 1 collaboration
Giada Fiorentini 1 collaboration
Sara Minghetti 1 collaboration
Abdulsalam A M Alkhaldi 1 collaboration
Ashraf K El-Damasy 1 collaboration
Mohammed S Abdel-Maksoud 1 collaboration
Tarfah Al-Warhi 1 collaboration
Davide Moi 1 collaboration
Alessandro Deplano 1 collaboration
Zeid A AlOthman 1 collaboration
Valentina Piras 1 collaboration
Gianfranco Balboni 1 collaboration
Valentina Onnis 1 collaboration
Iacopo Bertacchi 1 collaboration
Gennaro Catone 1 collaboration
Francesca Mannucci 1 collaboration
John E Lochman 1 collaboration
Ali Irfan 1 collaboration
Fozia Batool 1 collaboration
Syeda Andleeb Zahra Naqvi 1 collaboration
Amjad Islam 1 collaboration
Annika Valtari 1 collaboration
Marika Ruponen 1 collaboration
Elisa Toropainen 1 collaboration
Alexander Kovalenko 1 collaboration
Maxim Gureev 1 collaboration
Dmitry Dar'in 1 collaboration
Arto Urtti 1 collaboration
Carlo Buonanno 1 collaboration
Anna Gallani 1 collaboration
Giuseppe Grossi 1 collaboration
Valentina Levantini 1 collaboration
Annarita Milone 1 collaboration
Randall T Salekin 1 collaboration
Gianluca Sesso 1 collaboration
Gabriele Masi 1 collaboration
Mostafa M Elbadawi 1 collaboration
Mohamed A Abdelgawad 1 collaboration
Khalid S Alharbi 1 collaboration
Reem Odi 1 collaboration
Natalia Erenburg 1 collaboration
Chanan Shaul 1 collaboration
Moataz Shaldam 1 collaboration
Tamer M Ibrahim 1 collaboration
Doretta Cuffaro 1 collaboration
Lidia Ciccone 1 collaboration
Elisabetta Orlandini 1 collaboration
Susanna Nencetti 1 collaboration
Elisa Nuti 1 collaboration
Armando Rossello 1 collaboration
Abdeslem Bouzina 1 collaboration
Malika Berredjem 1 collaboration
Zouhair Bouaziz 1 collaboration
Joachim Jose 1 collaboration
Marc Le Borgne 1 collaboration
Christelle Marminon 1 collaboration
Irene Fusco 1 collaboration
Lisa Gaviano 1 collaboration
Simone Pratesi 1 collaboration
Carlo Dani 1 collaboration
Davide Sbravati 1 collaboration
Alessandro Casnati 1 collaboration
Francesco Sansone 1 collaboration
Damiano Cirri 1 collaboration
Ulf Ryde 1 collaboration
Justin Bergmann 1 collaboration
Francesca Binacchi 1 collaboration
Alessandro Pratesi 1 collaboration
Luigi Messori 1 collaboration
Haytham O Tawfik 1 collaboration
Moataz A Shaldam 1 collaboration
Silvia Pratesi 1 collaboration
Damiano Tanini 1 collaboration
Antonella Capperucci 1 collaboration
Mahmoud A El Hassab 1 collaboration
Nahla A Abdelshafi 1 collaboration
Rana A Eissa 1 collaboration
Nadeen H Diab 1 collaboration
Ekram H Mohamed 1 collaboration
Mamdouh A Oraby 1 collaboration
Rana G Eissa 1 collaboration
Mahmoud Elsabahy 1 collaboration
Noura G Eissa 1 collaboration
Sravan Jonnalagadda 1 collaboration
Fatema T Zahra 1 collaboration
Constantinos M Mikelis 1 collaboration
Pietro Cappelletto 1 collaboration
Benedetta Taddei 1 collaboration
Silvia Taddei 1 collaboration
Miguel Gallardo 1 collaboration
Rodrigo Arancibia 1 collaboration
David Villaman 1 collaboration
Patricia M Toro 1 collaboration
Michelle Muñoz-Osses 1 collaboration
Carolina Mascayano 1 collaboration
Andrea Ammara 1 collaboration
Hanan A Alghulikah 1 collaboration
Jacob Combs 1 collaboration
Jacob Andring 1 collaboration
Silvia Sgambellone 1 collaboration
Andrea Scaloni 1 collaboration