Barriers to successful dichoptic treatment for amblyopia in young children.


Journal

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
ISSN: 1435-702X
Titre abrégé: Graefes Arch Clin Exp Ophthalmol
Pays: Germany
ID NLM: 8205248

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 28 09 2020
accepted: 07 04 2021
revised: 13 03 2021
pubmed: 1 6 2021
medline: 1 10 2021
entrez: 31 5 2021
Statut: ppublish

Résumé

In an ongoing randomised clinical trial comparing dichoptic VR video games with patching for amblyopia, we evaluated any potential barriers to successful use of this novel amblyopia treatment method. From December 2017, all newly diagnosed amblyopic children were recruited. Excluded were children under age 4 and patients with strabismus exceeding 30PD. The video game was played for 1 h per week at the outpatient clinic under direct supervision. Records were kept of difficulties encountered during treatment and categorised into domains. Factors influencing the successful completion of this treatment were identified and related to patient characteristics. Ninety-one children were recruited for the trial, 20 parents refused participation before randomisation, because of the logistical challenges the outpatient dichoptic treatment would cause them. Of the 17 children who commenced dichoptic treatment (median age 6.2 years; IQR 4.9-8.4 years), 10 did not complete treatment. Children under age 5.5 years were unable to comprehend the game settings or the game itself. Older children (N = 7; 41%) were less willing to comply with the video game. Loss of interest in the game (N = 8; 47%) was found to be a limiting factor at all ages. Half of the children failed to complete VR dichoptic treatment, mainly due to young age. In countries with nationwide screening where amblyopia is detected before age 6, the applicability of such dichoptic treatment is limited.

Identifiants

pubmed: 34057550
doi: 10.1007/s00417-021-05193-1
pii: 10.1007/s00417-021-05193-1
pmc: PMC8478762
doi:

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

3149-3157

Informations de copyright

© 2021. The Author(s).

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Auteurs

Aveen Kadhum (A)

Department of Ophthalmology, Erasmus Medical Center, Room Ee 1663, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

Emily T C Tan (ETC)

Department of Ophthalmology, Erasmus Medical Center, Room Ee 1663, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

Dennis M Levi (DM)

School of Optometry, Graduate Group in Vision Science and Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA.

Linda Colpa (L)

Program in Neuroscience and Mental Health, The Hospital for Sick Children, Toronto, Canada.

Maria Fronius (M)

Department of Ophthalmology, Child Vision Research Unit, Goethe University, Frankfurt am Main, Germany.

Huibert J Simonsz (HJ)

Department of Ophthalmology, Erasmus Medical Center, Room Ee 1663, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

Sjoukje E Loudon (SE)

Department of Ophthalmology, Erasmus Medical Center, Room Ee 1663, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands. s.loudon@erasmusmc.nl.

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