Ectopic pregnancy: a single-center experience over ten years.
Abdominal Pain
/ physiopathology
Abortifacient Agents, Nonsteroidal
/ therapeutic use
Adult
Cesarean Section
/ statistics & numerical data
Chorionic Gonadotropin, beta Subunit, Human
/ blood
Douglas' Pouch
Female
Humans
Incidence
Intrauterine Devices
Laparoscopy
Length of Stay
/ statistics & numerical data
Methotrexate
/ therapeutic use
Middle Aged
Pregnancy
Pregnancy, Ectopic
/ blood
Pregnancy, Heterotopic
/ blood
Pregnancy, Ovarian
/ blood
Pregnancy, Tubal
/ blood
Reproductive Techniques, Assisted
/ statistics & numerical data
Retrospective Studies
Risk Factors
Salpingectomy
Salpingostomy
Smoking
/ epidemiology
Young Adult
Dizygotic ectopic
Ectopic pregnancy
Heterotopic pregnancy
β-HCG
Journal
Reproductive biology and endocrinology : RB&E
ISSN: 1477-7827
Titre abrégé: Reprod Biol Endocrinol
Pays: England
ID NLM: 101153627
Informations de publication
Date de publication:
01 Jun 2021
01 Jun 2021
Historique:
received:
16
04
2021
accepted:
12
05
2021
entrez:
1
6
2021
pubmed:
2
6
2021
medline:
1
1
2022
Statut:
epublish
Résumé
The aim of this study was to investigate characteristics associated with ectopic pregnancy (EP) that could be utilized for predicting morbidity or mortality. This was a retrospective analysis of pregnancy-related records from a tertiary center over a period of ten years. Data on age, gravidity, parity, EP risk, amenorrhea duration, abdominal pain presence and location, β-human chorionic gonadotropin (β-HCG) level, ultrasound findings, therapeutic intervention, exact EP implantation site and length of hospital stay (LOS) were obtained from the database. The LOS was used as a proxy for morbidity and was tested for an association with all variables. All statistical analyses were conducted with Stata® (ver. 16.1, Texas, USA). The incidence of EP in a cohort of 30,247 pregnancies over a ten-year period was 1.05%. Patients presented with lower abdominal pain in 87.9% of cases, and the likelihood of experiencing pain was tenfold higher if fluid was detectable in the pouch of Douglas. Only 5.1% of patients had a detectable embryonic heartbeat, and 18.15% had one or more risk factors for EP. While most EPs were tubal, 2% were ovarian. The LOS was 1.9 days, and laparoscopic intervention was the main management procedure. The cohort included one genetically proven dizygotic heterotopic pregnancy (incidence, 3.3 × 10 EP is a relatively common condition affecting approximately 1% of all pregnancies. β-HCG correlates with EP-related morbidity, but the overall morbidity rate of EP is low regardless of the implantation site. Laparoscopic surgery is an effective therapeutic procedure that is safe for managing EP, even in cases of heterotopic pregnancy.
Identifiants
pubmed: 34059064
doi: 10.1186/s12958-021-00761-w
pii: 10.1186/s12958-021-00761-w
pmc: PMC8166577
doi:
Substances chimiques
Abortifacient Agents, Nonsteroidal
0
Chorionic Gonadotropin, beta Subunit, Human
0
Methotrexate
YL5FZ2Y5U1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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