Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury.
Acute Kidney Injury
/ metabolism
Adult
Aged
Animals
Arachidonic Acids
/ metabolism
Caenorhabditis elegans
/ metabolism
Caloric Restriction
/ methods
Disease Models, Animal
Endocannabinoids
/ metabolism
Female
Humans
Kidney
/ metabolism
Longevity
/ physiology
Male
Mice
Mice, Inbred C57BL
Middle Aged
Polyunsaturated Alkamides
/ metabolism
Reperfusion Injury
/ metabolism
acute kidney injury
anandamide
caloric restriction
endocannabinoid
ischemia-reperfusion injury
preconditioning
stress resistance
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
22 May 2021
22 May 2021
Historique:
received:
22
04
2021
revised:
12
05
2021
accepted:
18
05
2021
entrez:
2
6
2021
pubmed:
3
6
2021
medline:
17
6
2021
Statut:
epublish
Résumé
Acute kidney injury (AKI) is a frequent and critical complication in the clinical setting. In rodents, AKI can be effectively prevented through caloric restriction (CR), which has also been shown to increase lifespan in many species. In
Identifiants
pubmed: 34067475
pii: ijms22115485
doi: 10.3390/ijms22115485
pmc: PMC8196977
pii:
doi:
Substances chimiques
Arachidonic Acids
0
Endocannabinoids
0
Polyunsaturated Alkamides
0
anandamide
UR5G69TJKH
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : FI 773/15-1
Organisme : Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen
ID : Nachwuchsgruppen.NRW 2015-2021
Organisme : Deutsche Forschungsgemeinschaft
ID : CRU329
Organisme : Deutsche Forschungsgemeinschaft
ID : CECAD, EXC 2030 - 390661388
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