Fish Sidestream-Derived Protein Hydrolysates Suppress DSS-Induced Colitis by Modulating Intestinal Inflammation in Mice.
IL-10
IL-6
chemokines
colitis
cytokines
fish protein hydrolysates
inflammation
Journal
Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729
Informations de publication
Date de publication:
28 May 2021
28 May 2021
Historique:
received:
02
04
2021
revised:
25
05
2021
accepted:
26
05
2021
entrez:
2
6
2021
pubmed:
3
6
2021
medline:
15
12
2021
Statut:
epublish
Résumé
Inflammatory bowel disease is characterized by extensive intestinal inflammation, and therapies against the disease target suppression of the inflammatory cascade. Nutrition has been closely linked to the development and suppression of inflammatory bowel disease, which to a large extent is attributed to the complex immunomodulatory properties of nutrients. Diets containing fish have been suggested to promote health and suppress inflammatory diseases. Even though most of the health-promoting properties of fish-derived nutrients are attributed to fish oil, the potential health-promoting properties of fish protein have not been investigated. Fish sidestreams contain large amounts of proteins, currently unexploited, with potential anti-inflammatory properties, and may possess additional benefits through bioactive peptides and free amino acids. In this project, we utilized fish protein hydrolysates, based on mackerel and salmon heads and backbones, as well as flounder skin collagen. Mice fed with a diet supplemented with different fish sidestream-derived protein hydrolysates (5%
Identifiants
pubmed: 34071180
pii: md19060312
doi: 10.3390/md19060312
pmc: PMC8228426
pii:
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Cytokines
0
Protein Hydrolysates
0
Waste Products
0
Dextran Sulfate
9042-14-2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Horizon 2020 Framework Programme
ID : 790956
Organisme : General secreteriat for Research and Technology Hellas
ID : MIS 5002670
Références
J Clin Med. 2021 Feb 19;10(4):
pubmed: 33669579
Am J Physiol Gastrointest Liver Physiol. 2006 Nov;291(5):G803-11
pubmed: 16728728
Front Cell Infect Microbiol. 2014 Feb 28;4:28
pubmed: 24616886
Nutrients. 2017 Mar 21;9(3):
pubmed: 28335546
Front Immunol. 2019 Jan 15;9:3183
pubmed: 30697218
Mar Drugs. 2021 Feb 26;19(3):
pubmed: 33652919
Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9517-22
pubmed: 22647600
Gastroenterology. 2009 Feb;136(2):564-74.e2
pubmed: 19027739
Prostaglandins Leukot Essent Fatty Acids. 2014 Dec;91(6):289-97
pubmed: 25451558
J Immunol. 2011 May 15;186(10):5993-6003
pubmed: 21498668
Curr Protoc Immunol. 2014 Feb 04;104:15.25.1-15.25.14
pubmed: 24510619
Int J Mol Sci. 2019 Sep 30;20(19):
pubmed: 31574900
Cell Res. 2020 Jun;30(6):492-506
pubmed: 32433595
Nat Rev Gastroenterol Hepatol. 2020 Apr;17(4):223-237
pubmed: 32076145
Front Immunol. 2019 Apr 26;10:919
pubmed: 31105710
BMC Med. 2019 Jul 23;17(1):142
pubmed: 31331324
J Food Sci Technol. 2020 Jun;57(6):2079-2088
pubmed: 32431334
Nat Clin Pract Gastroenterol Hepatol. 2006 Jul;3(7):390-407
pubmed: 16819502
Korean J Physiol Pharmacol. 2014 Aug;18(4):279-88
pubmed: 25177159
Int J Mol Sci. 2020 Jul 08;21(14):
pubmed: 32650452
Mar Drugs. 2021 May 11;19(5):
pubmed: 34064922
J Pharmacol Exp Ther. 2009 Apr;329(1):123-9
pubmed: 19131582
Cell. 2010 Mar 19;140(6):859-70
pubmed: 20303876
Cancer Res. 2009 Oct 1;69(19):7884-92
pubmed: 19773434
J Immunol. 2017 Feb 1;198(3):1006-1014
pubmed: 28115590
Curr Opin Pharmacol. 2009 Dec;9(6):688-96
pubmed: 19734090
Biochem Soc Trans. 2005 Apr;33(Pt 2):423-7
pubmed: 15787620
Mar Drugs. 2019 Dec 06;17(12):
pubmed: 31817754
Nature. 2014 Jan 23;505(7484):559-63
pubmed: 24336217
Mol Nutr Food Res. 2018 Sep;62(17):e1800088
pubmed: 29932491
J Gastroenterol. 2017 Jul;52(7):777-787
pubmed: 28534191
J Nutr. 2006 Jun;136(6):1558-64
pubmed: 16702321
Intest Res. 2019 Apr;17(2):171-176
pubmed: 30508476
PLoS One. 2014 Feb 05;9(2):e88335
pubmed: 24505477
Gastroenterology. 2003 Sep;125(3):775-85
pubmed: 12949723
Nutrients. 2021 Mar 10;13(3):
pubmed: 33801883
JPEN J Parenter Enteral Nutr. 2016 Nov;40(8):1131-1139
pubmed: 25855577
Front Immunol. 2020 Mar 31;11:551
pubmed: 32296441
Mar Drugs. 2019 Feb 02;17(2):
pubmed: 30717366
J Crohns Colitis. 2016 Nov;10(11):1351-1361
pubmed: 27194533
Crit Rev Food Sci Nutr. 2016 Jun 10;56(8):1370-8
pubmed: 25569442
Am J Physiol Renal Physiol. 2013 Nov 15;305(10):F1422-7
pubmed: 23986515
Clin Exp Immunol. 2009 Dec;158(3):325-33
pubmed: 19793338
Curr Top Microbiol Immunol. 2014;380:19-38
pubmed: 25004812
Nat Rev Gastroenterol Hepatol. 2019 Sep;16(9):531-543
pubmed: 31312042
J Biomed Biotechnol. 2012;2012:718617
pubmed: 22665990
Surg Clin North Am. 2019 Dec;99(6):1051-1062
pubmed: 31676047
Histol Histopathol. 2016 Nov;31(11):1259-70
pubmed: 26979994
FEBS J. 2018 Aug;285(16):2944-2971
pubmed: 29637711
Nutrients. 2017 Aug 23;9(9):
pubmed: 28832517
Sci Rep. 2016 Aug 05;6:30802
pubmed: 27492684
Eur J Nutr. 2020 Feb;59(1):1-17
pubmed: 30680455
Mar Drugs. 2014 Dec 05;12(12):5881-901
pubmed: 25490254
Genome Biol. 2012 Apr 16;13(9):R79
pubmed: 23013615
Sci Rep. 2016 Jun 15;6:27634
pubmed: 27302484
Am J Physiol Gastrointest Liver Physiol. 2020 Nov 1;319(5):G589-G608
pubmed: 32902315
J Nutr Biochem. 2013 Apr;24(4):700-5
pubmed: 22841543
Int J Biochem Cell Biol. 2018 Jan;94:40-43
pubmed: 29191734
Inflamm Bowel Dis. 2014 Apr;20(4):723-31
pubmed: 24583479
Int J Cancer. 2014 Sep 15;135(6):1297-306
pubmed: 24510316
Bioengineered. 2020 Dec;11(1):628-639
pubmed: 33034242
World J Gastroenterol. 2017 Sep 7;23(33):6016-6029
pubmed: 28970718
Cell Host Microbe. 2017 Dec 13;22(6):733-745.e5
pubmed: 29241040
Nature. 2011 Jun 15;474(7351):298-306
pubmed: 21677746
Gastroenterology. 2017 Feb;152(2):398-414.e6
pubmed: 27793606
Inflamm Bowel Dis. 2013 Mar;19(3):650-61
pubmed: 23328774
Comp Biochem Physiol B Biochem Mol Biol. 2007 Mar;146(3):395-401
pubmed: 17208480