Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
31 May 2021
Historique:
received: 22 04 2021
revised: 26 05 2021
accepted: 28 05 2021
entrez: 2 6 2021
pubmed: 3 6 2021
medline: 22 7 2021
Statut: epublish

Résumé

Mutations in the X-linked cyclin-dependent kinase-like 5 (

Identifiants

pubmed: 34073043
pii: ijms22115950
doi: 10.3390/ijms22115950
pmc: PMC8198396
pii:
doi:

Substances chimiques

Histone Deacetylase Inhibitors 0
Glycogen Synthase Kinase 3 beta EC 2.7.11.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Fondazione Telethon
ID : GGP19045
Organisme : Italian association:CDKL5 insieme verso la cura
ID : Ciani

Références

Expert Opin Investig Drugs. 2009 May;18(5):573-84
pubmed: 19388875
Nat Cell Biol. 2012 Sep;14(9):911-23
pubmed: 22922712
Nat Protoc. 2012 Sep;7(9):1741-54
pubmed: 22936216
ACS Chem Neurosci. 2012 Nov 21;3(11):963-71
pubmed: 23173075
Cell Signal. 2009 Feb;21(2):264-73
pubmed: 19007880
Front Cell Neurosci. 2016 Nov 28;10:261
pubmed: 27965538
J Neurochem. 2003 Oct;87(2):407-16
pubmed: 14511118
Nat Med. 2005 Oct;11(10):1088-95
pubmed: 16155577
Brain. 2008 Oct;131(Pt 10):2647-61
pubmed: 18790821
Hum Mol Genet. 2016 Sep 15;25(18):3887-3907
pubmed: 27466189
Front Biol (Beijing). 2012 Jun;7(3):212-220
pubmed: 25688261
Int J Neuropsychopharmacol. 2012 Nov;15(10):1525-34
pubmed: 22093169
Nat Rev Drug Discov. 2008 Oct;7(10):854-68
pubmed: 18827828
Hum Mol Genet. 2017 Sep 15;26(18):3520-3530
pubmed: 28641386
J Biol Chem. 2005 Oct 14;280(41):34908-16
pubmed: 16051598
Genomics. 1998 Aug 1;51(3):427-33
pubmed: 9721213
Anal Biochem. 1976 May 7;72:248-54
pubmed: 942051
J Neurosci Res. 2013 Sep;91(9):1133-42
pubmed: 23686642
PLoS One. 2016 Jun 17;11(6):e0157758
pubmed: 27315173
Biol Psychiatry. 2016 Aug 15;80(4):302-311
pubmed: 26452614
Neurobiol Dis. 2015 Oct;82:298-310
pubmed: 26143616
Hum Mol Genet. 2018 May 1;27(9):1572-1592
pubmed: 29474534
Neurobiol Dis. 2014 Oct;70:53-68
pubmed: 24952363
Epilepsia. 2019 Aug;60(8):1733-1742
pubmed: 31313283
Mol Med. 2011 May-Jun;17(5-6):448-56
pubmed: 21274503
Cell. 2005 Jan 14;120(1):137-49
pubmed: 15652488
Mol Neurobiol. 2020 May;57(5):2244-2262
pubmed: 32002787
ACS Med Chem Lett. 2019 Feb 04;10(4):469-474
pubmed: 30996781
Mol Cell. 2007 Jan 12;25(1):151-9
pubmed: 17218278
Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21516-21
pubmed: 23236174
Neuropharmacology. 2020 May 1;167:107746
pubmed: 31469994
Biochem J. 2001 Oct 1;359(Pt 1):1-16
pubmed: 11563964
Curr Drug Targets. 2006 Nov;7(11):1421-34
pubmed: 17100582
Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19599-604
pubmed: 19884510
Eur J Neurosci. 2018 May;47(9):1054-1066
pubmed: 29603837
Nat Rev Drug Discov. 2007 Jun;6(6):464-79
pubmed: 17541419
PLoS One. 2010 May 26;5(5):e10848
pubmed: 20520769
Neurotherapeutics. 2010 Oct;7(4):354-65
pubmed: 20880500
Aging Dis. 2021 Jun 1;12(3):764-785
pubmed: 34094641
Neurobiol Dis. 2021 Jun;153:105304
pubmed: 33621640
Curr Med Chem. 2017;24(37):4104-4120
pubmed: 28215142
PLoS One. 2016 Feb 05;11(2):e0148634
pubmed: 26849555
PLoS One. 2014 May 16;9(5):e91613
pubmed: 24838000
Ann Transl Med. 2015 Jun;3(10):136
pubmed: 26207229
Trends Neurosci. 2007 Apr;30(4):142-9
pubmed: 17324475
Orphanet J Rare Dis. 2016 Apr 14;11:39
pubmed: 27080038
Neural Plast. 2020 May 27;2020:4245821
pubmed: 32565775
Brain Pathol. 2019 Sep;29(5):658-674
pubmed: 30793413
Neural Plast. 2018 May 27;2018:9726950
pubmed: 29977282
Pediatr Neurol. 2019 Aug;97:38-42
pubmed: 31147226
Seizure. 2018 Jul;59:132-140
pubmed: 29852413
Curr Pharm Biotechnol. 2007 Dec;8(6):388-400
pubmed: 18289048
J Neuroinflammation. 2014 Jan 21;11:12
pubmed: 24447857
Hum Mol Genet. 2019 Sep 1;28(17):2851-2861
pubmed: 31108505
Mol Cell Biol. 2008 Mar;28(5):1688-701
pubmed: 18180281
Neurobiol Dis. 2020 May;138:104791
pubmed: 32032735
Front Pharmacol. 2020 Apr 24;11:537
pubmed: 32390854
J Neuropathol Exp Neurol. 2013 Mar;72(3):178-85
pubmed: 23399896
Oncogene. 2003 Dec 8;22(56):8983-98
pubmed: 14663477
Front Cell Neurosci. 2019 Apr 30;13:169
pubmed: 31114483
Drug News Perspect. 2009 Nov;22(9):513-24
pubmed: 20072728
Int J Alzheimers Dis. 2011;2011:189728
pubmed: 21660241
FEBS J. 2013 Feb;280(3):775-93
pubmed: 23181831
Naunyn Schmiedebergs Arch Pharmacol. 2015 Mar;388(3):337-49
pubmed: 25547373
EMBO J. 2003 Mar 3;22(5):1168-79
pubmed: 12606581
Nat Cell Biol. 2016 Sep;18(9):954-966
pubmed: 27501329
Eur J Hum Genet. 2013 Mar;21(3):266-73
pubmed: 22872100
Philos Trans R Soc Lond B Biol Sci. 2013 Dec 02;369(1633):20130134
pubmed: 24298137
Mol Neurodegener. 2013 Jan 29;8:7
pubmed: 23356410
Neurochem Int. 2012 Oct;61(5):666-71
pubmed: 22796213
Science. 1995 Jun 16;268(5217):1578-84
pubmed: 7777856

Auteurs

Manuela Loi (M)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Piazza di Porta San Donato 2, 40126 Bologna, Italy.

Laura Gennaccaro (L)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Piazza di Porta San Donato 2, 40126 Bologna, Italy.

Claudia Fuchs (C)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Piazza di Porta San Donato 2, 40126 Bologna, Italy.

Stefania Trazzi (S)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Piazza di Porta San Donato 2, 40126 Bologna, Italy.

Giorgio Medici (G)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Piazza di Porta San Donato 2, 40126 Bologna, Italy.

Giuseppe Galvani (G)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Piazza di Porta San Donato 2, 40126 Bologna, Italy.

Nicola Mottolese (N)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Piazza di Porta San Donato 2, 40126 Bologna, Italy.

Marianna Tassinari (M)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Piazza di Porta San Donato 2, 40126 Bologna, Italy.

Roberto Rimondini Giorgini (RR)

Department of Medical and Clinical Sciences, University of Bologna, 40126 Bologna, Italy.

Andrea Milelli (A)

Department for Life Quality Studies, University of Bologna, 47921 Rimini, Italy.

Elisabetta Ciani (E)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Piazza di Porta San Donato 2, 40126 Bologna, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH