Adaptative Steered Molecular Dynamics Study of Mutagenesis Effects on Calcium Affinity in the Regulatory Domain of Cardiac Troponin C.
Journal
Journal of chemical information and modeling
ISSN: 1549-960X
Titre abrégé: J Chem Inf Model
Pays: United States
ID NLM: 101230060
Informations de publication
Date de publication:
28 06 2021
28 06 2021
Historique:
pubmed:
4
6
2021
medline:
10
8
2021
entrez:
3
6
2021
Statut:
ppublish
Résumé
Calcium-dependent cardiac muscle contraction is regulated by the protein complex troponin (cTn) and specifically by the regulatory N-terminal domain (N-cTnC) which contains one active Ca
Identifiants
pubmed: 34080877
doi: 10.1021/acs.jcim.1c00419
pmc: PMC8350873
mid: NIHMS1728332
doi:
Substances chimiques
Troponin C
0
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
3052-3057Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL137015
Pays : United States
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