Heart failure as a complication of COVID-19 infection: systematic review and meta-analysis.
COVID-19
Heart failure
incidence
mortality
Journal
Acta cardiologica
ISSN: 1784-973X
Titre abrégé: Acta Cardiol
Pays: England
ID NLM: 0370570
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
pubmed:
4
6
2021
medline:
15
4
2022
entrez:
3
6
2021
Statut:
ppublish
Résumé
The prevalence and prognostic implications of heart failure (HF), as a complication of COVID-19 infection remains unclear. We performed a systematic review and metanalysis aimed to evaluate the pooled incidence of acute HF as a cardiac complication of COVID-19 disease and to estimate the related mortality risk in these patients. Data were obtained searching MEDLINE, Scopus and Web of Science for all investigations published any time to 26 December 2020. If statistical heterogeneity was 50%, the results were derived from the fixed-effects model otherwise the random-effects model. Overall, 1064 patients [mean age 66 years, 618 males] were included in the final analysis reviewing six investigations. The cumulative in-hospital rate of COVID-19 patients complicated by acute HF ranged between 6.9 and 63.4% among the studies reviewed. A random effect model revealed a pooled incidence of COVID-19 patients complicated by acute HF in 20.2% of cases (95% CI: 11.1-33.9%, Acute HF represents a frequent complication of COVID-19 infection associated with a higher risk of mortality in the short-term period.
Sections du résumé
BACKGROUND/OBJECTIVES
OBJECTIVE
The prevalence and prognostic implications of heart failure (HF), as a complication of COVID-19 infection remains unclear. We performed a systematic review and metanalysis aimed to evaluate the pooled incidence of acute HF as a cardiac complication of COVID-19 disease and to estimate the related mortality risk in these patients.
METHODS
METHODS
Data were obtained searching MEDLINE, Scopus and Web of Science for all investigations published any time to 26 December 2020. If statistical heterogeneity was 50%, the results were derived from the fixed-effects model otherwise the random-effects model.
RESULTS
RESULTS
Overall, 1064 patients [mean age 66 years, 618 males] were included in the final analysis reviewing six investigations. The cumulative in-hospital rate of COVID-19 patients complicated by acute HF ranged between 6.9 and 63.4% among the studies reviewed. A random effect model revealed a pooled incidence of COVID-19 patients complicated by acute HF in 20.2% of cases (95% CI: 11.1-33.9%,
CONCLUSIONS
CONCLUSIONS
Acute HF represents a frequent complication of COVID-19 infection associated with a higher risk of mortality in the short-term period.
Identifiants
pubmed: 34080948
doi: 10.1080/00015385.2021.1890925
doi:
Types de publication
Journal Article
Meta-Analysis
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM